Entertainment Quiz / Pathoma Chapter 2 pt2

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Can you name the Pathoma Chapter 2 pt2

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What type of hypersensitivity is Sjogren's
Receptor editing in B cells is facilitated by which gene
Binding of antigen by CD4 cell without second signal leads to what
Where are the stem cells for the skin
What type of collagen is in the basement membrane
What is the marker for hematopoietic stem cells
Provide nutrients during granulation
What are the specific Anti-ribonucleoproteins, Anti-
Thrombocytopenia, eczema, reccurent infections
What disease is highly associated with IgA deficiency
Is APA syndrome more commonly primary or secondary to SLE?
Second most common cause of death in diffuse scleroderma involves what organ
Most common and most sever renal injury for SLE pts
What does a keloid have excess of
What percent of people with early complement deficiency develop lupus
What is increased in Scleroderma that is a potent vasocontrictor
Cells that present single positive cells with many self antigens
Selection type in thymus that checks binding to self antigen
Anemia, thromboytopenia, and leukopenia are due to what type of hypersensitivity in SLE
CREST symptoms are for what subtype of scleroderma
Antibodies are to what in diffuse scleroderma
Drug that induces SLE (TB Tx)
Deposit type III collagen during granulation
Do drug induced SLE pts get renal damage commonly?
Deficiency in C5-C9, increased risk for infections with ?
tightness of skin, loss of wrinkles on fingers
Autoantibodies present in Sjogrens syndrome, Anti-
Mutatated protein in X linked agammaglobulinemia
Which HLA subtype is associated with ankylosing spondylitis
S in CREST
Child with two very swollen eylids
Lack of thymus, lack of parathyroids, abnormalities in heart, great vessels, face
Tissue that is quiescent but can reenter cell cycle
R in CREST
Features of SLE, Systemic sclerosis, polymyositis, autoimmune
Which antibody produces a false positive test for syphillis
African american females, CNS psychosis, renal damage
Sudden onset of acute renal failure and hypertension, diffuse scleroderma
Etiology in SCID (enzyme)
Developmental failure of 3d and 4th pouches
Autoimmune lymphoproliferative syndrome is cause by a defect in what pathway
APA plus hypercoaguble state is called
What must be avoided in XLG babies
IPEX syndrome is caused by mutations in what?
Antibodies against host nuclear material
What type of collagen makes up cartilage
Fibroblast growth factor, inhibits inflammation
Disease with mutated CD40L or CD40, no class switching
Complete lack of Ig's
What does the biopsy exclude as causes for destruction of salivary gland
Antibodies are to what in limited scleroderma
What is necessary for crosslinking of glycine and lysine by lysyl oxidase
Polyendocrine syndrome is caused by a mutation in what protein
Initial phase of repair
What element is necessar for collagenase to remove type III collagen
What would be seen on biopsy that is diagnostic of Sjogrens
Contract would during granulation
CD4+ CD25+(IL2r) FoxP3+
Antigen-antibody complex (Type III) deposition on multiple tissue
What is a hypertrophic scar made up of predominantly
Small vegetation on both sides of mitral valve
Inheritance pattern for Wiskott-aldrich syndrome
What is the 5 year survival for SLE
Etiology in SCID (cell surface)
What part of the thymus does positive selection occur
Hereditary angioedema of skin, periorbital membranes, and mucosal surfaces
Most common Ig deficiency
Of dry eyes/mouth, ANA/ASSA/ASSB, and biopsy, how many need to be positive for Dx of Sjogrens
What type of collagen makes up vasculature, granulation tissue, embryonic tissue
Which Anti-ANA has prognostic value and predics renal damage
Are drug induced SLE pts ANA+
Hardening of tissue, deposition of collagen, systemic
What is necessary for hydroxylation of glycine and lysine
What cytokine is necessary for survival of Tregs
Growth factor in angiogenesis, skeletal development
Which ANA are specific for lupus
Drug that induces SLE (Antiarrythmic)
What can anti SSA,SSB cause in children
What deficiency disposes an individual to SLE
Defective cell mediated and humoral immunities
Where are the stem cells for the bowels
What type of cells suppress Tcells by competitive binding of CTLA4 to CD28
What is present in the serum of pts with Sjogrens
Tx of DiGeorge pt
T in CREST
What is the stem cell of the lung
What are Sjogrens pts at a higher risk for late in the disease
Growth factor in angiogenesis
E in CREST
immunodysregulation polyendocrinopathy enteropathy X-linked
What part of the thymus does negative selection occur
Lymphocytic destruction of salivary and lacrimal glands
In scar formation, type III collagen is replaced by what type of collagen
What is the cardiovascular complication for late SLE
ANA with serum antibodies against U1 ribonucleoprotein
Libman-Sacks endocarditis, Arthritis
Disease with low IgG due to defects in B or T cells
Drug that induces SLE (Smooth muscle relaxant)
Epithelial and fibroblast growth factor
What type of selection is the checkpoint between double positive and single positive cells, also called MHC restriction
How long after birth do XLG babies present with symptoms
Tyrosine phosphatase that has mutations associated with autoimmune disorders
Oral or nasopharyngeal ulcers, discoid rash, arthritis, peripheral vasospasm
Cell surface marker for monocyte lineage (macrophages)
Most common cause of death in diffuse scleroderma involves what organ
Most commonly involved organ system in diffuse scleroderma
Infections in CVID and X linked agammaglobulinemia pts
C in CREST
Endothelium, smooth muscle, fibroblast growth factor

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Created May 15, 2014ReportFavoriteNominate
Tags:chapter, Pt 2

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