Science Quiz / cancers

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Can you name the cancers

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usually presents as osteolytic lesions on xray
most common benign primary tumore of bone
malignant found in medulla of pelvis or central skeleon
underlying condition that leads to 'brown tumor'
what is secreted in hypercalcemia of malignancy
proliferation of osteoblasts in teenagers and elderly
hypothyroidism in children
amennorhea due to loss of basalis
reinke crystal, excess androgens
cafe au lait, fibrous dysplasia,
Malignant proliferation of cells in breast lobule
malignant proliferation of cells within the duct
Mutation in MEN2b
self limited, painful thyroiditis after viral infection
most important prognostitic factor for breast cancer
Only tumor arising form epiphysis, soap bubble
increases the risk for breast carcinoma 5x
inflammation of subareolar duct/ Vit A deficiency/ squamous metaplasia of duct
ductal carcinoma in situ that has walked its way out of the duct
Parathyroid, Pancreas, Pituitary adenomas
due to truama, calcification on mammagraphy
arises metaphyseal regoin, lifts periosteom, cellular atypia
arrest of ovum
extensive infiltration of thyroid on histo by lymphocytes, hurthle cells
malignant in males, benign in females
testicular, may form glands, 20-30yrs old, hemmorage, necrosis
diagnosis of papillary carcinoma is based on
architecture of hyperplasia pathway carcinoma
elevated AFP, Schiller duvall bodies
Drug associated with clear cell carcinoma of vagina
lumpy upper outer quadrant, most common in premenopause
homer wright rosettes, sheets of small round cells
most common benign neoplasm of breast
three tissues that experience osmotic damage in DMII
Elevated b-HCG
benign, usually found in small bones of hands and feet
what drug is associated with endometrial polyp
achlorhydria, gallstones, steatorrhea
must be present to dx as chronic endometritis
elevated ESR, fever, leukocytosis, age 10-15
mutation associacted with sporadic pathway endo carcinoma
testes, malignant, MOST COMMON in children
local mass, 100% mortality, inactivation of p53
bloody nipple discharge, premenopausal
most common bilateral of testes
most common cause of asymptomatic hypercalcemia
what is the major mechanism in hyperosmolar nonketotic coma
most common neoplasm in testes of adults
triad of preeclampsia
treatment resistant gastic ulcers in the jejunum, (zollinger ellison syndrome))
most important predictor for progression of endometrial hyperplasia to carcinoma
associated with gardners syndrome
Glucose over 500, hypotension, coma, NO KETONES
most common nongerm cell neoplasm in testes
episodic hypoglycemia that is relived by glucose, high insulin, high C peptide
most common site of osteosarcoma in under25yrs
most common ovarian tumor (70%)
what color does amyloid show with congo red stain
orphan annie eyes, grooves, intranuclear inclusion, Somoma bodies
gene rearrangments in papillary carcinoma of thyroid
infolding borders, scalloped edges, exoptholmos
hypothyroidism in adults
cystadenoma, mucinous or serous in postmenopausal 60-70
cystadenoma, mucinous or serous in premenopausal 30-40
most common cause of symptomatic hypercalcemia
characterized by increased LH to FSH ratio
translocation in ewings
10-20 years, Thyroid medullary, pheochromocytoma, parathyroid
bone tumor relieved with aspirin
krukenberg, pseudomyxoma peritonei
diGeorge syndrome causes an absence of
fibrosis of thyroid, extends to other structures
thyroid and adrenal medullary carcinomas, marfanoid habitus, mucosal ganglioneuromas, NO PARATHYROID INVOLVMENT
how would you detect ductal carcinoma in situ
Meigs syndrome (+PE + ascities)
Arises in diaphysis, neuro ectoderm, small blue cells
low t3, low t4, increased tsh, low 131 uptake
snow storm appearance, passing of grapes
neuroendocrine neoplasm derived from parafollicular C cells, amyloid deposition
onion skin layering of bone
architecture of sporadic pathway endo carcinoma
marker is LDH, Responds well to radiotherapy

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