Science Quiz / CLS2 - Cancer

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CLS2 - Cancer

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Score 0/40 Timer 15:00
What cell cycle checkpoint monitors spindle formation?
What term describes a tumour that has a complete loss of differentiation?
What term describes a variation in tumour size and shape?
What is the suffix for a malignant tumour of mesenchymal origin?
What enzyme to cancer cells re-activate to avoid senescence?
What famous oncogene is created by a translocation?
Which type of Hodgkins lymphoma has the worst prognosis?
What does a normal cell go into when it has reached it's finite proliferative capacity?
Proto-oncogenes require what kind of mutation to become oncogenes?
A decrease in which pro-apoptotic factor can lead to colorectal cancer?
What do we call something that can cause DNA damage and lead to cancer?
What is the most common type of brain tumour?
What term describes 'abnormal increase in the number of normal cells'?
What term describes 'an abnormal mass of tissue which continues to grow after the stimulus has been removed'?
What is the name of programmed cell death?
What are HCG, AFP and PSA examples of?
What cell is characteristic of Hodgkins lymphoma?
Radiotherapy kills tumour cells due to ...
What is the suffix for a benign mesenchymal tumour?
What gene is associated with an increased risk of breast/ovarian cancer?
Duke's staging is specific for what type of cancer?
The degree of tumour differentiation is used to define what?
c-jun, c-myc and c-fos are examples of what?
What term describes a dark staining nuclei due to increased nuclear DNA?
Growth factors initiate which signalling cascade pathway?
What chemotherapy agent binds tubulin subunits? (Clue:Not to be confused with methotrexate!)
VEGF can be targeted by which drug?
Cdk1 activity relies on what?
Angiogenesis is promoted by what factor?
The TNM criteria is used to assess what about a tumour?
Name a cancer with a very poor prognosis
In what phase of the cell cycle is new DNA synthesised?
What disease is a mutation in the Rb tumour suppressor gene associated with?
Cell repair gene hMLH1/2 is associated with what type of cancer syndrome?
What do we call a mutation that doesn't lead to cancer?
What do you call a epithelial dysplasia that has not crossed the basement membrane?
What's the name of a common diagnostic test for cervical cancer?
What do you call a benign epithelial tumour of glandular origin?
What do you call a malignant epithelial tumour of squamous origin?
What tumour suppressor gene is regarded as the 'Guardian of the genome'?

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