Fluoxetine, paroxetine, sertraline, escitalopram, fluvoxamine, citalopram Treatment of choice for depression, panic attacks, OCD, social anxiety disorder, PTSD, General Anxiety Disorder
Venlafaxine, Duloxetine Approved for General Anxiety Disorder and pain associated with peripheral neuropathy for diabetes mellitus
Phenelzine, Tranylcypromine, Selegiline Dietary restrictions due to risk of tyramine induced hypertension
Atypical antidepressant; no effect on reuptake; antihistaminic effect leads to somnolence; can lead to priapism in males
Atypical antidepressant; weak neuronal uptake of 5-HT, NE, and DA; downregulates adrenergic receptors; minimal weight gain and sexual side effects; does not help anxiety; FDA appro
Atypical antidepressant; noradrenergic and specific serotonergic antidepressant; no effect on reuptake; antihistaminic effect leads to somnolence
Treat Panic, Anxiety, and acute sleep disorders; rapid effect; muscle relaxant; decrease all components of sleep except for stage 2; Alprazolam, Clonazepam, Flunitrazepam (roofies) Side effects: sedation, anterograde amnesia, deadly interaction with alcohol, tolerance develops to sleep effects
Treat Generalized anxiety disorder, not effective for Panid d.o.; 5-HT 1A partial agonist; must be taken steadily for 1-2 weeks to have beneficial effect
Antihistamine used in patients with history of alcohol or sedative abuse Not effective for Panic Disorders
Used for insomnia Not effective for Panic Disorders
Clonidine and prazosin treat nightmares due to PTSD
Effects similar to BZD but not structurally related to BZD; sedative/hypnotic
First line treatment for acute mania; side effects: diabetes insipidis, hypothyroidism, congenital malformation
First line treatment for acute mania; also used for epilepsy, migraines prophylaxis, acute and prophylactic treatment for bipolar; black box warnings: hepatotoxicity, teratogenicit
Treats psychotic/hyperkinetic mania; related to clozapine but safer; adverse effect: metabolic syndrome
Treats depression without causing mania; prophylactic for bipolar disorder; adverse effect: Stevens-Johnson syndrome rash
Atypical antipsychotic that has minimal EPS and risk of tardive dyskinesia; adverse effect: agranulocytosis
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