Science Quiz / Pharmacodynamics I and II

Random Science Quiz

Can you name the Pharmacodynamics I and II?

 Plays Quiz not verified by Sporcle

Forced Order
Score 0/27 Timer 10:00
Site at which the engogenous transmitter binds
The ______ the theraputic index, the better.
Site other than the active site on the receptor
Can affinity of an agnonist be measured from a dose-response curve?
Type of binding: binds to orthosteric/active site on receptor.
Disassociation constant for a drug - a measure of affinity. [d][r]/[dr]
How well a drug activates the system
Dose of antagonist needed to shift the dose-response curve 2-fold to the right. (-log Ka)
Does competitive binding affect shape of dose-response curve?
This kind of agonist gives the maximal effect of which the system is capable.
The ______ the pA2, the better the antagonist affinity.
Effect of a drug increases with an increase in dose (or concentration) up to a maximum.
The smaller the KD value, the _________ the affinity.
Type of binding: binds at an allosteric site.
A measure of the affinity of a competitive antagonist for its receptor. [A][R]/[AR]
How well a drug binds to its receptor
Effect of increasing doses of drug across a population - drug does or does not cuase a specific effect in an individual.
Percent of receptors bound. [DR]/[RT]
Can competitive binding be overcome by increasing ligand?
A measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Concentration of drug ([D]) that gives 50% maximal effect.
Law of ____ ______: rate of a reaction is proportional to the concentation of the reactants.
A drug that binds to a receptor but produces no direct response. Stabilizes inactive conformations of receptors.
This kind of agonist gives a lesser effect than a full agonist, even when all receptors are occupied.
Can non-competitive binding be overcome by increasing ligand?
Antagonist binding that operates through activation of a different pathway.
A drug that binds to a receptor and activates it to produce a respose.

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Join for Free
Log In

You Might Also Like...

Show Comments


Created Oct 13, 2012ReportFavoriteNominate

Top Quizzes Today

Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.

Report this User

Report this user for behavior that violates our Community Guidelines.