stimulates basal and post-prandial insulin secretion (sulfonylureas)
stimulates basal and post-prandial insulin secretion, faster acting (meglitinides)
potentiates action of insulin in liver > muscle by activating AMPK in liver and muscle
potentiates action of insulin in muscle and adipose > liver, activates PPARgamma in adipose tissue
delays absorption of CHO by inhibiting alpha-glucosidase
agonize GLP-1 receptor in pancreas, ANS, and brain
enhances effects on endogenous incretins by inhibiting DPPIV
amylin analog (enhances satiety, slows gastric emptying, inhibits post-prandial glucagon secretion)
increases renal excretion of glucose by inhibiting SGLT2, glucose reabsorption in the proximal tubule
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