Science Quiz / FA USMLE Rapid Review Classic Labs/Findings

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Can you name the FA USMLE Classic Labs/Findings?

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Labs/FindingsDisease/DisorderExtra info
Anti-ACh receptor antibodies
Anti-voltage gated calcium channel antibodies
Pseudopalisading tumor cells on brain biopsy
'Delta-wave' on EKG, short PR interval, supraventricular tachycardia
CA19-9
Podocyte fusion or 'effacement' on electron microscopy
'Nutmeg' appearance of liver
Mucin-filled cell with peripheral nucleus
'Boot-shaped' heart on x-ray
Antimitochondrial antibodies (AMAs)
CA125
Eosinophilic cytoplasmic inclusion in neuron
Iron-containing nodules in alveolar septum
Stippled vaginal epithelial cells
'Onion skin' periosteal reaction
Thrombi made of white/red layers
WBC casts in urine
Heterophile antibodies
Anti-topoisomerase antibodies
Renal epithelial casts in urine
Keratin pearls on a skin biopsy
MPO-ANCA/p-ANCA
CA27-29/CA15-3
Mammary gland ('blue domed') cyst
'Lumpy bumpy' appearance of glomeruli on immunofluorescence
Antinuclear antibodies (ANAs: anti-Smith and anti-dsDNA)
Depigmentation of neurons in substantia nigra
Branching Gram+ rods with sulfur granules
Basophilic stippling of RBCs
Low cortisol with high ACTH and high MSH
'Apple-core' lesion on barium enema x-ray
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ('starry sky' histology)
'Lead pipe' appearance of colon on abdominal imaging
'Brown' tumor of bone
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
'Spikes' on basement membrane, 'dome-like' subepithelial deposits
Eosinophilic globule in liver
Needle-shaped, negatively birefringent crystals
PR3-ANCA/c-ANCA
Hypertension, hypokalemia, metabolic acidosis
Raised periosteum ('Codman triangle')
Monoclonal antibody spike
Enlarged thyroid cells with ground-glass nuclei with central clearing
Hypercoagulability (leading to migrating DVTs and vasculitis) secondary to malignancy
'Wire loop' glomerular capillary appearance on light microscopy
Desquamated epithelium casts in sputum
Glomerulus-like structure surrounding vessel in germ cells of ovary; elevated AFP
Hypochromic, microcytic anemia
Anti-glutamic acid decarboxylase (GAD-65) antibodies
Protein aggregates in neurons from hyperphosphorylation of tau protein
Psammoma bodies
Intranuclear eosinophilic droplet-like bodies
Ring-enhancing brain lesion on CT/MRI in AIDS
Recurrent infections, eczema, thrombocytopenia
Circular grouping of dark tumor cells surrounding pale neurofibrils
Polished, 'ivory-like' appearance of bone at cartilage erosion
Lytic ('punched-out') bone lesions on x-ray
Colonies of mucoid Pseudomonas in lungs
Bloody or yellow tap on lumbar puncture
'Tennis racket-shaped' cytoplasmic organelles (EM) in Langerhans cells
Extracellular amyloid deposition in gray matter of brain
hCG elevation
Novobiocin sensitive
'Steeple' sign on frontal CXR
RBC casts in urine
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons
Anti-transgluatminase/anti-gliadin/anti-endomysial antibodies
Thousands of polyps on colonoscopy
Anti-TSH receptor
Heart nodules (granulomatous)
Low serum ceruloplasmin
Antiphospholipase-A2 receptor antibodies
Narrowing of bowel lumen on barium x-ray
Antiplatelet antibodies
Anti-cyclic citrullinated peptide (CCP)/Anti-IgG antibodies
Hypersegmented neutrophils
Rhomboid crystals, positively birefringent
High level of D-dimers
Degeneration of dorsal column fibers
Antimicrosomal, antithyroglobulin
Cardiomegaly with apical atrophy
Electrical alternans (alternating amplitude on EKG)
Anti-glomerular basement membrane antibodies
Yellowish CSF
Silver-staining spherical aggregation of tau proteins in neurons
Anticentromere antibodies
Basophilic nuclear remnants in RBCs
Increased AFP in amniotic fluid/maternal serum
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
anti-Jo, anti-SRP, anti-Mi-2 antibodies
Antiparietal cell antibodies
Increased uric acid levels
'Waxy' casts with very low urine flow
Streptococcus bovis bacteremia
Bronchogenic apical lung tumor on imaging
Green-brown nipple discharge
Large granules in phagocytes, immunodeficiency
Hexagonal, double-pointed, needle-like crystals in bronchial secretions
Giant B cells with bilobed nuclei with prominent inclusions ('owl's eye')
Low cortisol and low ACTH
Bloody (or serous) nipple discharge
Optochin sensitive
Finely granular, homogenous, eosinophilic inclusions in hepatic cytosol
Cellular crescents in Bowman capsule
Atypical lymphocytes
'Hair on end' ('Crew-cut') appearance on x-ray
Dysplastic squamous cervical cells with 'raisinoid' nucluei and hyperchromasia
Rosenthal fibers in brain tumor with hair-like processes
Eosinophilic cytoplasmic inclusion in liver cell
Triglyceride accumulation in liver cell vacuoles
Azurophilic-peroxidase+ granular inclusions in granulocytes and myeloblasts
Stacks of RBCs
'Bamboo spine' on x-ray
Anti-desmoglein (anti-desmosome) antibodies
Decreased AFP in amniotic fluid/maternal serum
Diarrayed granulosa cells arranged around collections of eosinophilic fluid
'Chocolate cyst' of ovary
Nodular hyaline deposits in glomeruli
'Honeycomb lung' on x-ray
Linear appearance of IgG deposition on glomerular and alveolar basement membranes
Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Anti-SSA, anti-SSB (anti-Ro, anti-La) antibodies
Antihistone antibodies
Lymphoid aggregates with germinal centers in thyroid
Homer-Wright rosettes, Bombesin/NSE+, N-myc overexpression
'Soap bubble' in femur or tibia on x-ray
WBCs that look 'smudged'
Rib notching (inferior surface on x-ray)
'Tram-track' appearance of capillary loops of glomerular basement membranes on light microscopy

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