Science Quiz / FA USMLE Rapid Review Classic Labs/Findings

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Can you name the FA USMLE Classic Labs/Findings?

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Labs/FindingsDisease/DisorderExtra info
Podocyte fusion or 'effacement' on electron microscopy
Anti-topoisomerase antibodies
'Hair on end' ('Crew-cut') appearance on x-ray
Antinuclear antibodies (ANAs: anti-Smith and anti-dsDNA)
Narrowing of bowel lumen on barium x-ray
Large granules in phagocytes, immunodeficiency
Bronchogenic apical lung tumor on imaging
'Tram-track' appearance of capillary loops of glomerular basement membranes on light microscopy
Hypersegmented neutrophils
Bloody or yellow tap on lumbar puncture
Cellular crescents in Bowman capsule
Antihistone antibodies
CA19-9
Antimitochondrial antibodies (AMAs)
Mucin-filled cell with peripheral nucleus
Recurrent infections, eczema, thrombocytopenia
Anti-cyclic citrullinated peptide (CCP)/Anti-IgG antibodies
Eosinophilic globule in liver
Psammoma bodies
Raised periosteum ('Codman triangle')
Anti-glutamic acid decarboxylase (GAD-65) antibodies
Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Heterophile antibodies
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
Pseudopalisading tumor cells on brain biopsy
Stacks of RBCs
Diarrayed granulosa cells arranged around collections of eosinophilic fluid
Renal epithelial casts in urine
Lytic ('punched-out') bone lesions on x-ray
Homer-Wright rosettes, Bombesin/NSE+, N-myc overexpression
Anti-SSA, anti-SSB (anti-Ro, anti-La) antibodies
'Tennis racket-shaped' cytoplasmic organelles (EM) in Langerhans cells
Anti-TSH receptor
Antiphospholipase-A2 receptor antibodies
Linear appearance of IgG deposition on glomerular and alveolar basement membranes
Increased uric acid levels
Basophilic nuclear remnants in RBCs
Nodular hyaline deposits in glomeruli
Optochin sensitive
Antiplatelet antibodies
Antimicrosomal, antithyroglobulin
'Boot-shaped' heart on x-ray
High level of D-dimers
Cardiomegaly with apical atrophy
MPO-ANCA/p-ANCA
Anti-glomerular basement membrane antibodies
WBCs that look 'smudged'
Lymphoid aggregates with germinal centers in thyroid
Extracellular amyloid deposition in gray matter of brain
Monoclonal antibody spike
Antiparietal cell antibodies
Giant B cells with bilobed nuclei with prominent inclusions ('owl's eye')
Protein aggregates in neurons from hyperphosphorylation of tau protein
Circular grouping of dark tumor cells surrounding pale neurofibrils
'Wire loop' glomerular capillary appearance on light microscopy
Thrombi made of white/red layers
anti-Jo, anti-SRP, anti-Mi-2 antibodies
'Nutmeg' appearance of liver
Decreased AFP in amniotic fluid/maternal serum
Yellowish CSF
Green-brown nipple discharge
Heart nodules (granulomatous)
Eosinophilic cytoplasmic inclusion in neuron
Hypercoagulability (leading to migrating DVTs and vasculitis) secondary to malignancy
Branching Gram+ rods with sulfur granules
Anti-voltage gated calcium channel antibodies
Depigmentation of neurons in substantia nigra
Anti-transgluatminase/anti-gliadin/anti-endomysial antibodies
Colonies of mucoid Pseudomonas in lungs
Low serum ceruloplasmin
'Delta-wave' on EKG, short PR interval, supraventricular tachycardia
hCG elevation
'Brown' tumor of bone
Hypertension, hypokalemia, metabolic acidosis
Eosinophilic cytoplasmic inclusion in liver cell
Electrical alternans (alternating amplitude on EKG)
Silver-staining spherical aggregation of tau proteins in neurons
'Lead pipe' appearance of colon on abdominal imaging
Polished, 'ivory-like' appearance of bone at cartilage erosion
Anti-desmoglein (anti-desmosome) antibodies
'Bamboo spine' on x-ray
Triglyceride accumulation in liver cell vacuoles
'Soap bubble' in femur or tibia on x-ray
Glomerulus-like structure surrounding vessel in germ cells of ovary; elevated AFP
Degeneration of dorsal column fibers
Intranuclear eosinophilic droplet-like bodies
Anticentromere antibodies
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
Anti-ACh receptor antibodies
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ('starry sky' histology)
Rosenthal fibers in brain tumor with hair-like processes
Azurophilic-peroxidase+ granular inclusions in granulocytes and myeloblasts
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons
Rib notching (inferior surface on x-ray)
Bloody (or serous) nipple discharge
'Apple-core' lesion on barium enema x-ray
'Chocolate cyst' of ovary
'Waxy' casts with very low urine flow
Novobiocin sensitive
WBC casts in urine
Low cortisol with high ACTH and high MSH
Needle-shaped, negatively birefringent crystals
Atypical lymphocytes
Rhomboid crystals, positively birefringent
Hypochromic, microcytic anemia
Low cortisol and low ACTH
'Honeycomb lung' on x-ray
Basophilic stippling of RBCs
CA27-29/CA15-3
Ring-enhancing brain lesion on CT/MRI in AIDS
CA125
'Onion skin' periosteal reaction
'Spikes' on basement membrane, 'dome-like' subepithelial deposits
'Steeple' sign on frontal CXR
Iron-containing nodules in alveolar septum
'Lumpy bumpy' appearance of glomeruli on immunofluorescence
Increased AFP in amniotic fluid/maternal serum
Desquamated epithelium casts in sputum
PR3-ANCA/c-ANCA
Keratin pearls on a skin biopsy
Dysplastic squamous cervical cells with 'raisinoid' nucluei and hyperchromasia
Stippled vaginal epithelial cells
Thousands of polyps on colonoscopy
Enlarged thyroid cells with ground-glass nuclei with central clearing
RBC casts in urine
Streptococcus bovis bacteremia
Hexagonal, double-pointed, needle-like crystals in bronchial secretions
Mammary gland ('blue domed') cyst
Finely granular, homogenous, eosinophilic inclusions in hepatic cytosol

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