Science Quiz / FA USMLE Rapid Review Classic Labs/Findings

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Can you name the FA USMLE Classic Labs/Findings?

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Labs/FindingsDisease/DisorderExtra info
'Lumpy bumpy' appearance of glomeruli on immunofluorescence
Eosinophilic cytoplasmic inclusion in liver cell
Rosenthal fibers in brain tumor with hair-like processes
'Nutmeg' appearance of liver
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons
Hypersegmented neutrophils
Anti-topoisomerase antibodies
Heart nodules (granulomatous)
Pseudopalisading tumor cells on brain biopsy
Raised periosteum ('Codman triangle')
Green-brown nipple discharge
Anti-glutamic acid decarboxylase (GAD-65) antibodies
Podocyte fusion or 'effacement' on electron microscopy
Colonies of mucoid Pseudomonas in lungs
Dysplastic squamous cervical cells with 'raisinoid' nucluei and hyperchromasia
Hypercoagulability (leading to migrating DVTs and vasculitis) secondary to malignancy
'Tram-track' appearance of capillary loops of glomerular basement membranes on light microscopy
'Onion skin' periosteal reaction
'Soap bubble' in femur or tibia on x-ray
Large granules in phagocytes, immunodeficiency
Diarrayed granulosa cells arranged around collections of eosinophilic fluid
Keratin pearls on a skin biopsy
'Wire loop' glomerular capillary appearance on light microscopy
'Brown' tumor of bone
Hypochromic, microcytic anemia
Extracellular amyloid deposition in gray matter of brain
Triglyceride accumulation in liver cell vacuoles
Optochin sensitive
Homer-Wright rosettes, Bombesin/NSE+, N-myc overexpression
Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Basophilic nuclear remnants in RBCs
Anti-SSA, anti-SSB (anti-Ro, anti-La) antibodies
Anti-voltage gated calcium channel antibodies
'Honeycomb lung' on x-ray
Recurrent infections, eczema, thrombocytopenia
Cardiomegaly with apical atrophy
Hexagonal, double-pointed, needle-like crystals in bronchial secretions
Degeneration of dorsal column fibers
Eosinophilic globule in liver
'Waxy' casts with very low urine flow
Rib notching (inferior surface on x-ray)
Needle-shaped, negatively birefringent crystals
Mammary gland ('blue domed') cyst
Finely granular, homogenous, eosinophilic inclusions in hepatic cytosol
Low serum ceruloplasmin
Nodular hyaline deposits in glomeruli
Glomerulus-like structure surrounding vessel in germ cells of ovary; elevated AFP
Antiparietal cell antibodies
Stippled vaginal epithelial cells
Antimicrosomal, antithyroglobulin
Desquamated epithelium casts in sputum
Increased AFP in amniotic fluid/maternal serum
Anti-transgluatminase/anti-gliadin/anti-endomysial antibodies
Lymphoid aggregates with germinal centers in thyroid
Antimitochondrial antibodies (AMAs)
Ring-enhancing brain lesion on CT/MRI in AIDS
Azurophilic-peroxidase+ granular inclusions in granulocytes and myeloblasts
Atypical lymphocytes
High level of D-dimers
'Lead pipe' appearance of colon on abdominal imaging
Rhomboid crystals, positively birefringent
Mucin-filled cell with peripheral nucleus
Hypertension, hypokalemia, metabolic acidosis
Monoclonal antibody spike
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
Narrowing of bowel lumen on barium x-ray
Anti-glomerular basement membrane antibodies
Cellular crescents in Bowman capsule
'Hair on end' ('Crew-cut') appearance on x-ray
Branching Gram+ rods with sulfur granules
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ('starry sky' histology)
'Steeple' sign on frontal CXR
'Delta-wave' on EKG, short PR interval, supraventricular tachycardia
Lytic ('punched-out') bone lesions on x-ray
RBC casts in urine
WBCs that look 'smudged'
Depigmentation of neurons in substantia nigra
Linear appearance of IgG deposition on glomerular and alveolar basement membranes
Antiphospholipase-A2 receptor antibodies
anti-Jo, anti-SRP, anti-Mi-2 antibodies
Thrombi made of white/red layers
Anti-ACh receptor antibodies
Antinuclear antibodies (ANAs: anti-Smith and anti-dsDNA)
Antiplatelet antibodies
Streptococcus bovis bacteremia
Protein aggregates in neurons from hyperphosphorylation of tau protein
Low cortisol and low ACTH
Bloody (or serous) nipple discharge
Anti-cyclic citrullinated peptide (CCP)/Anti-IgG antibodies
Bronchogenic apical lung tumor on imaging
'Apple-core' lesion on barium enema x-ray
'Bamboo spine' on x-ray
Anticentromere antibodies
Psammoma bodies
'Spikes' on basement membrane, 'dome-like' subepithelial deposits
Bloody or yellow tap on lumbar puncture
Polished, 'ivory-like' appearance of bone at cartilage erosion
Antihistone antibodies
Giant B cells with bilobed nuclei with prominent inclusions ('owl's eye')
Silver-staining spherical aggregation of tau proteins in neurons
Yellowish CSF
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
Intranuclear eosinophilic droplet-like bodies
Heterophile antibodies
Renal epithelial casts in urine
Stacks of RBCs
'Tennis racket-shaped' cytoplasmic organelles (EM) in Langerhans cells
Electrical alternans (alternating amplitude on EKG)
'Boot-shaped' heart on x-ray
hCG elevation
Enlarged thyroid cells with ground-glass nuclei with central clearing
Anti-TSH receptor
'Chocolate cyst' of ovary
Increased uric acid levels
Novobiocin sensitive
Thousands of polyps on colonoscopy
Anti-desmoglein (anti-desmosome) antibodies
Basophilic stippling of RBCs
Low cortisol with high ACTH and high MSH
Circular grouping of dark tumor cells surrounding pale neurofibrils
Eosinophilic cytoplasmic inclusion in neuron
Decreased AFP in amniotic fluid/maternal serum
WBC casts in urine
Iron-containing nodules in alveolar septum

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