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Can you name the FA USMLE Biochem Review?

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Name of highly condensed, transcriptionally inactive DNA
Less condensed, transcribed DNA
Molecular repression by:
Molecular activation by:
Xeroderma pigmentosum is caused by a defect in what type of repair?
Defective mismatch repair leads to what disease?
Start codon:
Stop codon:
Kozak Concensus Sequence
Shine-Dalgarno Sequence
Histone that is not in the core, responsible for binding each nucleosome together
Deamination of cytosine makes ____
Sequence (3 letters) at 3' aminoacyl end of all tRNA's
All cyclins are degraded by ____ ____ ____
Phosphorylated Rb is responsible for inhibiting what transcription factor?
Cyclin D couples with which CDK?
Cyclin E couples with which CDK?
The Golgi adds what molecule to enzymes destined for the lysosome?
Deficiency in that^ process causes what disease?
Organelle responsible for catabolism of very-long-chain fatty acids, branched-chain fatty acids, amino acids, and ethanol
Microfilaments are composed of what protein?
Intermediate filament class found in Mesenchymal tissue
Intermediate filament class found in Epithelial cells
Intermediate filament class found in Muscle cells
Intermediate filament class found in neuroglia (astrocytes, schwann cells, etc.)
Microtubules are composed of alpha and beta _____ (protein)
Either of two cancer drugs that inhibit the polymerization of microtubules
Either of two cancer drugs that hyperstabilize microtubules
Enzyme that crosslinks tropocollagen into collagen
Three amino acids necessary for purine synthesis
Vitamin derivative necessary for purine synthesis
Amino acid necessary for pyrimidine synthesis
Rate limiting step (enzyme) of pyrimidine synthesis
Drug that inhibits ribonucleotide reductase
Drug that inhibits thymidylate synthase
Either of two drugs that inhibit dihydrofolate reductase
Enzyme deficient in Orotic Aciduria
Enzyme that recycles guanine and hypoxanthine
Disorder caused by a deficiency in that^ enzyme
Two drugs that inhibit Uric acid production from Hypoxanthine/Xanthine
Enzyme that converts adenosine to inosine
Enzyme responsible for insulin-dependent conversion of glucose to G6P
Enzyme responsible for rate-limiting step of glycolysis
Enzyme that converts F6P to F1,6BP
Enzyme that converts F6P to F2,6BP
Gluconeogenesis: Enzyme that converts pyruvate to oxaloacetate
Gluconeogenesis: Enzyme that converts oxaloacetate to phosphoenolpyruvate
Gluconeogenesis: Enzyme that converts F1,6BP to F6P
Gluconeogenesis: Enzyme that converts G6P to glucose
Glycogenolysis: Enzyme that breaks down alpha-1,4 linkages
Glycogenolysis: Enzyme that breaks down alpha-1,6 linkage
G6PD deficiency prevents entry into what pathway
Inhibitor of Electron Transport Complex 1
Inhibitor of Electron Transport Complex 3
Inhibitor of Electron Transport Complex 4
ATP synthase inhibitor
Enzyme that is deficient in Essential Fructosuria
Enzyme that is deficient in Fructose Intolerance
Urine dipstick tests for what molecule only?
Lactose is made of what two sugars?
Sucrose is made of what two sugars?
Enzyme that converts Ornithine + Carbamoyl phosphate into Citrulline
Enzyme that converts Phenylalanine to Tyrosine
Disease caused by a deficiency in that^ enzyme
Enzyme that converts DOPA (dihydroxyphenylalanine) to Melanin
Disease caused by a deficiency in that^ enzyme
Disease: congenital deficiency of homogentisate oxidase
Either of two possible enzyme deficiencies in homocystinuria
Fatty acid synthesis begins with what TCA substrate
Apolipoprotein responsible for mediating chylomicron secretion out of enterocyte into lymphatics
Apolipoprotein needed for VLDL, IDL, and LDL to exit the liver
Apolipoprotein that mediates remnant uptake
Apolipoprotein that activates LCAT
Disease: absent or defective LDL receptors
Autoantibodies against Type IV Collagen:
Protein that is defective in Marfan syndrome:
Enzyme that handles superoxide (O2-)
Enzyme that handles hydrogen peroxide (H2O2)
Enzyme that handles hydroxide radical (hydroxyl)
Two residues that are hyroxylated on Collagen
Vitamin required for that^ step
Disease: deficiency in Type I Collagen
Deficiency in Type IV Collagen:
Enzyme that is deficient in Von Gierke disease (type I)
Enzyme that is deficient in Pompe disease (type II)
Enzyme that is deficient in Cori disease (type III)
Enzyme that is deficient in McArdle disease (type V)
Enzyme that is deficient in Fabry disease
Enzyme that is deficient in Gaucher disease
Enzyme that is deficient in Niemann-Pick disease
Enzyme that is deficient in Tay-Sachs disease
Enzyme that is deficient in Krabbe disease

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