Science Quiz / Viral Pathogenesis & Drugs

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Can you name the Viral Pathogenesis & Drugs?

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HBV, HPV, and HSV are diagnosed by this method.
Transmitted by direct contact usually from biting.
Drug used to treat CMV retinitis that requires Host Kinase. It must be administered with Probenecid to reduce nephrotoxicity.
Capsids are built from this.
Name a virus that can infect multiple organ systems.
Most viruses cause what type of infection?
What phase involves viral uncoating, DNA/RNA replication, and protein synthesis of the virus in the cell.
Phosphorylation independent drug used to treat CMV retinitis. It inhibits viral DNA/RNA polymerase and HIV reverse transcriptase.
A way for HIV, HBV, or polio to spread to secondary sites of infection.
Name an adverse reaction of Acyclovir
Viruses that infect the gut
An acyclic guanosine analog that is mediated by CMV-specific protein kinase phosphotransferase UL97. Competitively inhibits viral DNA polymerase and cause termination of DNA elonga
When viruses spread in the body.
Virus infection fails to be cleared by the immune system.
Most viruses are diagnosed by this method.
Drug that requires phosphorylations by host cell enzymes. May still have an effect even if the virus evolved the HSV Thymidine Kinase. Not for systemic use.
Drug that inhibits viral-cell fusion.
Viral infection diagnosed by electrom microscopy
Viral infection diagnosed by immunofluorescence.
When viruses clog up the cytosol or nucleus.
Converted to penicyclovir after oral administration.
Only dsRNA virus
L-valyl prodrug of acyclovir that is more effective in treating VZV than acyclovir
Entire structure of a virus.
Only ssDNA virus.
Viruses transferred by mosquito bites. Arthrood-borne viruses.
Type of infection that cause recurrent disease, no viral replication, invisible to immune system, and the host is infected for life.
Used by viruses to bind to cell surface receptors.
Adverse reaction of Ganciclovir.
Drug that competes with deoxyGTP for the viral DNA polymerase and causes chain termination following incorporation into viral DNA.
Used for CMV prophylaxis or CMV retinitis treatment
What phase involves viral assembly and intracellular virus is increasing.
Transmission by animal contact.
Initial or local symptoms (1-8 days) when systemic viruses first multiply locally.
Virus that causes gastroenteritis and lasts for 24-48 hours.
ssRNA that is used directly as mRNA
Protein coats that surround viral nucleic acids.
Diploid virus
An acyclic guanosine derivative that is active against HSV-1, HSV-2, and VZV.
Genome plus capsid

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