Science Quiz / Viral Pathogenesis & Drugs

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Can you name the Viral Pathogenesis & Drugs?

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Also try: Isaac Winners
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Only ssDNA virus.
Drug that requires phosphorylations by host cell enzymes. May still have an effect even if the virus evolved the HSV Thymidine Kinase. Not for systemic use.
An acyclic guanosine derivative that is active against HSV-1, HSV-2, and VZV.
Virus that causes gastroenteritis and lasts for 24-48 hours.
Drug used to treat CMV retinitis that requires Host Kinase. It must be administered with Probenecid to reduce nephrotoxicity.
Viral infection diagnosed by electrom microscopy
Genome plus capsid
When viruses clog up the cytosol or nucleus.
Drug that competes with deoxyGTP for the viral DNA polymerase and causes chain termination following incorporation into viral DNA.
Used for CMV prophylaxis or CMV retinitis treatment
HBV, HPV, and HSV are diagnosed by this method.
Diploid virus
Used by viruses to bind to cell surface receptors.
What phase involves viral uncoating, DNA/RNA replication, and protein synthesis of the virus in the cell.
Capsids are built from this.
Transmission by animal contact.
Most viruses cause what type of infection?
What phase involves viral assembly and intracellular virus is increasing.
Transmitted by direct contact usually from biting.
Drug that inhibits viral-cell fusion.
Converted to penicyclovir after oral administration.
Initial or local symptoms (1-8 days) when systemic viruses first multiply locally.
Virus infection fails to be cleared by the immune system.
Only dsRNA virus
L-valyl prodrug of acyclovir that is more effective in treating VZV than acyclovir
Name a virus that can infect multiple organ systems.
An acyclic guanosine analog that is mediated by CMV-specific protein kinase phosphotransferase UL97. Competitively inhibits viral DNA polymerase and cause termination of DNA elonga
A way for HIV, HBV, or polio to spread to secondary sites of infection.
Most viruses are diagnosed by this method.
Adverse reaction of Ganciclovir.
ssRNA that is used directly as mRNA
Viral infection diagnosed by immunofluorescence.
Viruses that infect the gut
Name an adverse reaction of Acyclovir
Phosphorylation independent drug used to treat CMV retinitis. It inhibits viral DNA/RNA polymerase and HIV reverse transcriptase.
Entire structure of a virus.
Type of infection that cause recurrent disease, no viral replication, invisible to immune system, and the host is infected for life.
When viruses spread in the body.
Protein coats that surround viral nucleic acids.
Viruses transferred by mosquito bites. Arthrood-borne viruses.

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