Science Quiz / Viral Pathogenesis & Drugs

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Can you name the Viral Pathogenesis & Drugs?

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L-valyl prodrug of acyclovir that is more effective in treating VZV than acyclovir
Most viruses cause what type of infection?
Phosphorylation independent drug used to treat CMV retinitis. It inhibits viral DNA/RNA polymerase and HIV reverse transcriptase.
Virus infection fails to be cleared by the immune system.
What phase involves viral uncoating, DNA/RNA replication, and protein synthesis of the virus in the cell.
A way for HIV, HBV, or polio to spread to secondary sites of infection.
HBV, HPV, and HSV are diagnosed by this method.
Only dsRNA virus
Viral infection diagnosed by immunofluorescence.
Transmitted by direct contact usually from biting.
Capsids are built from this.
Name an adverse reaction of Acyclovir
Entire structure of a virus.
What phase involves viral assembly and intracellular virus is increasing.
Type of infection that cause recurrent disease, no viral replication, invisible to immune system, and the host is infected for life.
Name a virus that can infect multiple organ systems.
Viruses transferred by mosquito bites. Arthrood-borne viruses.
Adverse reaction of Ganciclovir.
Drug that competes with deoxyGTP for the viral DNA polymerase and causes chain termination following incorporation into viral DNA.
Used by viruses to bind to cell surface receptors.
Protein coats that surround viral nucleic acids.
Viruses that infect the gut
When viruses spread in the body.
Drug that inhibits viral-cell fusion.
Viral infection diagnosed by electrom microscopy
Most viruses are diagnosed by this method.
ssRNA that is used directly as mRNA
Virus that causes gastroenteritis and lasts for 24-48 hours.
An acyclic guanosine analog that is mediated by CMV-specific protein kinase phosphotransferase UL97. Competitively inhibits viral DNA polymerase and cause termination of DNA elonga
Genome plus capsid
Drug used to treat CMV retinitis that requires Host Kinase. It must be administered with Probenecid to reduce nephrotoxicity.
Initial or local symptoms (1-8 days) when systemic viruses first multiply locally.
Used for CMV prophylaxis or CMV retinitis treatment
Converted to penicyclovir after oral administration.
An acyclic guanosine derivative that is active against HSV-1, HSV-2, and VZV.
When viruses clog up the cytosol or nucleus.
Diploid virus
Transmission by animal contact.
Drug that requires phosphorylations by host cell enzymes. May still have an effect even if the virus evolved the HSV Thymidine Kinase. Not for systemic use.
Only ssDNA virus.

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Created Nov 4, 2010ReportNominate
Tags:Nintendo Quiz, Drug, Viral

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