Science Quiz / Viral Pathogenesis & Drugs

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Can you name the Viral Pathogenesis & Drugs?

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Transmission by animal contact.
Converted to penicyclovir after oral administration.
L-valyl prodrug of acyclovir that is more effective in treating VZV than acyclovir
Only dsRNA virus
Name a virus that can infect multiple organ systems.
Used by viruses to bind to cell surface receptors.
Viral infection diagnosed by electrom microscopy
HBV, HPV, and HSV are diagnosed by this method.
Viruses that infect the gut
An acyclic guanosine analog that is mediated by CMV-specific protein kinase phosphotransferase UL97. Competitively inhibits viral DNA polymerase and cause termination of DNA elonga
Transmitted by direct contact usually from biting.
An acyclic guanosine derivative that is active against HSV-1, HSV-2, and VZV.
Most viruses are diagnosed by this method.
A way for HIV, HBV, or polio to spread to secondary sites of infection.
Drug that requires phosphorylations by host cell enzymes. May still have an effect even if the virus evolved the HSV Thymidine Kinase. Not for systemic use.
Drug used to treat CMV retinitis that requires Host Kinase. It must be administered with Probenecid to reduce nephrotoxicity.
Capsids are built from this.
Virus infection fails to be cleared by the immune system.
Used for CMV prophylaxis or CMV retinitis treatment
Drug that inhibits viral-cell fusion.
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Virus that causes gastroenteritis and lasts for 24-48 hours.
When viruses clog up the cytosol or nucleus.
Diploid virus
Entire structure of a virus.
Name an adverse reaction of Acyclovir
Initial or local symptoms (1-8 days) when systemic viruses first multiply locally.
When viruses spread in the body.
Viruses transferred by mosquito bites. Arthrood-borne viruses.
Most viruses cause what type of infection?
Genome plus capsid
Adverse reaction of Ganciclovir.
What phase involves viral assembly and intracellular virus is increasing.
Phosphorylation independent drug used to treat CMV retinitis. It inhibits viral DNA/RNA polymerase and HIV reverse transcriptase.
Type of infection that cause recurrent disease, no viral replication, invisible to immune system, and the host is infected for life.
ssRNA that is used directly as mRNA
Only ssDNA virus.
What phase involves viral uncoating, DNA/RNA replication, and protein synthesis of the virus in the cell.
Drug that competes with deoxyGTP for the viral DNA polymerase and causes chain termination following incorporation into viral DNA.
Protein coats that surround viral nucleic acids.
Viral infection diagnosed by immunofluorescence.

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