Science Quiz / Neoplasia V Fun

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Can you name the Neoplasia V Fun?

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Platinum analog that causes neurotoxicity
A Pyrimidine analog that inhibits Thymidylate Synthase and is used to treat colon and prostate cancer. Leucovorin potentiates its anti-cancer effect.
Folate analog that inhibits DHFR and causes myelosuppression and mucositis.
Topoisomerase II inhibitor. This drug is a type of Epipodophyllotoxin that inhibits the M phase of the cell cyle.
During Bone Marrow suppression, this is given to increase the number of White Blood Cells.
Type of drug that blocks the disassembly of microtubules and is used to treat breast cancer.
Type of drugs that has the prefix 'vin'
Topoisomerase II inhibitor. This drug is a type of antitumor antibiotic. Its toxicities include cardiotoxicity and 'hand foot syndrome'
A Guanine analog that interferes with guanine nucleotide synthesis. Its side effects include Tumor Lysis Syndrome.
mAB against CD52 protein
Type of Alkylating Agent that is highly lipophilic, can cross the BBB, and used to treat brain tumors.
mAB against ErbB-2/HER2/neu Receptor Tyrosine Kinase
Used to overcome the side effects of Methotrexate.
Ethyleneimine drug used to treat ovarian cancer
Alkyl-sulfonate drug used to treat CML.
Type of drug that prevents tubulin polymerization to form microtubules.
Targets BCR-ABL oncoprotein
Alkylating-related agent that is used to treat Hodgkin's Lymphoma and is in the WHO drug essential list.
Inhibits Ribonucleotide Reductase (RNR)
A mAB against VEGF
A Purine analog that interferes with purine nucleotide synthesis and used to treat leukemia
Topoisomerase I inhibitor. This drug is a type of Camptothecin.
Most commonly used DNA alkylating agent that treats leukemia and lymphoma. Its toxicities include bone marrow toxicity, haemorrhagic cystitis and liver damage.
Bleomycin, an antitumor antibiotic, inhibits what phase of the cell cycle?
A chimeric mAB against CD20 protein
Platinum analog that causes myelosuppression
Emetogenic effects of alkylating agents can be decreased by pretreatment with this receptor antagonist.
An antitumor antibiotic that induces DNA strand breaks by generating superoxide/hydroxide free radicals. It induces G2 arrest and its major side effect is pulmonary fibrosis.
Anti-Metabolites inhibit what phase of the cell cycle?
Type of drugs that has the suffix 'taxel'
Type of nitrosourea that is used to treat pancreatic cancer.
Low neutrophils during bone marrow suppression
Type of drugs that has the suffix 'bine'
Mitotic Inhibitors and Topoisomerase inhibitors inhibit what phase of the Cell cycle?
A type of anthracycline that is used to treat ALL and AML.
Platinum analog that has nephrotoxicity and need IV hydration so the drug can flushed out
A chimeric mAB against EGFR

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Created Oct 31, 2010ReportNominate

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