Science Quiz / Neoplasia V Fun

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Can you name the Neoplasia V Fun?

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Targets BCR-ABL oncoprotein
Platinum analog that causes neurotoxicity
A mAB against VEGF
A Guanine analog that interferes with guanine nucleotide synthesis. Its side effects include Tumor Lysis Syndrome.
Mitotic Inhibitors and Topoisomerase inhibitors inhibit what phase of the Cell cycle?
Type of drugs that has the prefix 'vin'
Used to overcome the side effects of Methotrexate.
Platinum analog that causes myelosuppression
A chimeric mAB against EGFR
A Purine analog that interferes with purine nucleotide synthesis and used to treat leukemia
Type of drug that prevents tubulin polymerization to form microtubules.
A chimeric mAB against CD20 protein
Type of Alkylating Agent that is highly lipophilic, can cross the BBB, and used to treat brain tumors.
Anti-Metabolites inhibit what phase of the cell cycle?
Bleomycin, an antitumor antibiotic, inhibits what phase of the cell cycle?
Topoisomerase I inhibitor. This drug is a type of Camptothecin.
A type of anthracycline that is used to treat ALL and AML.
Most commonly used DNA alkylating agent that treats leukemia and lymphoma. Its toxicities include bone marrow toxicity, haemorrhagic cystitis and liver damage.
An antitumor antibiotic that induces DNA strand breaks by generating superoxide/hydroxide free radicals. It induces G2 arrest and its major side effect is pulmonary fibrosis.
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mAB against ErbB-2/HER2/neu Receptor Tyrosine Kinase
Type of drug that blocks the disassembly of microtubules and is used to treat breast cancer.
Low neutrophils during bone marrow suppression
Topoisomerase II inhibitor. This drug is a type of antitumor antibiotic. Its toxicities include cardiotoxicity and 'hand foot syndrome'
A Pyrimidine analog that inhibits Thymidylate Synthase and is used to treat colon and prostate cancer. Leucovorin potentiates its anti-cancer effect.
Type of drugs that has the suffix 'taxel'
Alkyl-sulfonate drug used to treat CML.
Emetogenic effects of alkylating agents can be decreased by pretreatment with this receptor antagonist.
Topoisomerase II inhibitor. This drug is a type of Epipodophyllotoxin that inhibits the M phase of the cell cyle.
Alkylating-related agent that is used to treat Hodgkin's Lymphoma and is in the WHO drug essential list.
Folate analog that inhibits DHFR and causes myelosuppression and mucositis.
Inhibits Ribonucleotide Reductase (RNR)
Type of drugs that has the suffix 'bine'
mAB against CD52 protein
Type of nitrosourea that is used to treat pancreatic cancer.
Platinum analog that has nephrotoxicity and need IV hydration so the drug can flushed out
Ethyleneimine drug used to treat ovarian cancer
During Bone Marrow suppression, this is given to increase the number of White Blood Cells.

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