Science Quiz / Neoplasia V Fun

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Alkylating-related agent that is used to treat Hodgkin's Lymphoma and is in the WHO drug essential list.
Type of nitrosourea that is used to treat pancreatic cancer.
Most commonly used DNA alkylating agent that treats leukemia and lymphoma. Its toxicities include bone marrow toxicity, haemorrhagic cystitis and liver damage.
During Bone Marrow suppression, this is given to increase the number of White Blood Cells.
Topoisomerase II inhibitor. This drug is a type of Epipodophyllotoxin that inhibits the M phase of the cell cyle.
Platinum analog that causes neurotoxicity
A Guanine analog that interferes with guanine nucleotide synthesis. Its side effects include Tumor Lysis Syndrome.
An antitumor antibiotic that induces DNA strand breaks by generating superoxide/hydroxide free radicals. It induces G2 arrest and its major side effect is pulmonary fibrosis.
A mAB against VEGF
Type of drugs that has the suffix 'taxel'
Emetogenic effects of alkylating agents can be decreased by pretreatment with this receptor antagonist.
mAB against ErbB-2/HER2/neu Receptor Tyrosine Kinase
Anti-Metabolites inhibit what phase of the cell cycle?
Inhibits Ribonucleotide Reductase (RNR)
Platinum analog that has nephrotoxicity and need IV hydration so the drug can flushed out
A Purine analog that interferes with purine nucleotide synthesis and used to treat leukemia
Type of drugs that has the prefix 'vin'
Folate analog that inhibits DHFR and causes myelosuppression and mucositis.
Ethyleneimine drug used to treat ovarian cancer
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Type of drug that prevents tubulin polymerization to form microtubules.
Topoisomerase II inhibitor. This drug is a type of antitumor antibiotic. Its toxicities include cardiotoxicity and 'hand foot syndrome'
A chimeric mAB against EGFR
Alkyl-sulfonate drug used to treat CML.
Bleomycin, an antitumor antibiotic, inhibits what phase of the cell cycle?
Type of drugs that has the suffix 'bine'
Targets BCR-ABL oncoprotein
A type of anthracycline that is used to treat ALL and AML.
Topoisomerase I inhibitor. This drug is a type of Camptothecin.
A Pyrimidine analog that inhibits Thymidylate Synthase and is used to treat colon and prostate cancer. Leucovorin potentiates its anti-cancer effect.
Used to overcome the side effects of Methotrexate.
Platinum analog that causes myelosuppression
Mitotic Inhibitors and Topoisomerase inhibitors inhibit what phase of the Cell cycle?
mAB against CD52 protein
Type of Alkylating Agent that is highly lipophilic, can cross the BBB, and used to treat brain tumors.
A chimeric mAB against CD20 protein
Low neutrophils during bone marrow suppression
Type of drug that blocks the disassembly of microtubules and is used to treat breast cancer.
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Created Oct 31, 2010ReportNominate

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