Science Quiz / Hermel MidBlock 3 Lectures

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Can you name the Hermel MidBlock 3 Lectures?

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Heterozygosity of HLA, being null for chemokine receptor CCR5, and circumcision are __________ factors for AIDS
Lymphocyte trafficking inhibitor that targets alpha4 integrin and prevents lymphocyte entry into the brain or gut.
This treatment extends lifespan of HIV+ women.
Drug: Uses GM-CSF for recovery of bone marrow after stem cell transplantation.
Soluble CTLA-Ig fusion molecule and a competitive inhibitor of CD28. Prevents T cell activation of APCs.Used to treat RA.
Antibody deficiency disease where there is a total lack of Ig, mature B cells, and germinal centers in the lymph nodes or spleen. Patients lack tonsils and adenoids.
Parasite characteristic of AIDS
Bacteria characteristic of AIDS
Disease: makes antibodies to acetylcholine receptors. The consequence is progressive muscle weakness. This can be treated with cyclophosphamide.
Binds to CD33 on Leukemic cell. First FDA approved immunoconjugate.
Likelihood of developing certain autoimmune diseases in persons who inherit particular HLA alleles than in persons who lack these alleles.
Immunoconjugate that is not an antibody. Used to treat T cell lymphoma and Chronic lymphocytic leukemia (CLL)
Antibody deficiency disease where there are normal B cell numbers but poor antibody response to TD or TI antigens.
Virus characteristic of AIDS
Condition where damage to the eye causes the release of proteins never previously encountered by the immune system.
Detects antibodies to HIV. Cannot be used alone to diagnose HIV.
Disease that induces continuous synthesis and release of thyroid hormones. It is a Type II hypersensitivity in endocrine cells.
In Graft vs. Leukemia effect, patients surviving acute GVHD have reduced tumor __________
Fungi characteristic of AIDS
Skin blistering disease where autoantibodies are directed against epidermal antigens.
Drug that inhibits transcription of many inflammatory mediator genes. Side effect includes Cushing's syndrome
Targets Her2/Neu and treats breast cancer
Women tend to be more susceptible to autoimmune diseases except for this disease.
Rare disorder characterized by recurrent episodes of painless angioedema without urticaria or pruritis
Used in diagnosing autoimmune hemolytic anemia.
Allergy Intervention that keeps skin wet
Degranulation inhibitor that inhibits the release of LT, TNF, IL-4, IL-5 and other cytokines.
Inflammatory disease characterized by joint destruction. Can be treated with Methotrexate as the Gold Standard.
Phagocyte function deficiency: Defect in Lysosomal fusion
Graft between members of two different species
Drug: Uses IL-11 to treat thrombocytopenia
Drug: Uses G-CSF for bone marrow recovery after stem cell transplantation.
Type II hypersensitivity in blood via complement and FcR+ phagocytes and causes DIRECT CYTOTOXICITY.
Disease that has a diagnostic butterfly rash. Most common in females. Rash is caused by deposition of immune complexes in the skin. Type III hypersensitivity.
Type of SCID where there are defects in proteins involved in VDJ rearrangement or T cell signal transduction
Dominant genetic factor affecting susceptibility to autoimmune diseases.
Bronchodilator used as intervention for allergies.
Number of new HIV infections a day in 2008.
Graft from an individual to the same individual
Targets CD20 and treats RA, CLL, and B cell lymphoma
DNA alkylating agent used to prevent and reverse organ graft rejection. Toxicity is hemorrhagic cystitis and bone marrow toxicity.
Purine antagonist that treats RA and acute graft rejection. Contraindication is pancreatitis. Toxicity is myelosuppression.
MAb used as an immunosuppressant in organ transplantation.Binds to IL2R (CD25)
Inhibits mTOR and used in prevention of renal transplant rejection.
Th2 mediated inflammation of the airways. Type IV hypersensitivity. Chronic inflammation from Eosinophils leads to airway remodeling.
Disease from gluten allergy. HLA-DQ presents the modified peptide of gluten. Type IV hypersensitivity.
Type III hypersensitivity done experimentally. It is induced in skin by subcutaneous injection of the antigen.

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Created Nov 18, 2010ReportNominate

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