Science Quiz / Gugliucci Lectures

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Where coagulation factors are synthesized
Name a granule released by platelets
A disease where patients are photosensitive and the most common type of error in heme synthesis.
Activated by heparin and inactivates thrombin, Xa, and IXa
Accumulation of ALA and porphobillinogen in the urine and no photosensitization characterizes this disease caused by errors in heme synthesis.
A clinical sign characterized by yellow skin, sclera, and mucosa. Bilirubin is 3X above normal.
Most important of the plasminogen activators
A or B: N-acetyl glucosamine
Released by endothelial cells as anti-coagulant.
Degranulates, changes shape, and puts out 3 receptors when activated.
Coagulation cascade includes 1) tissue factor 2) phospholipid complex expression 3) thrombin activation and 4)__________
A,B,O are alleles of the same gene on a single locus on this chromosome
Used to cover the baby's Rh+ RBC
Inhibits clotting by proteolytic cleavage of factor Va and VIIIa
A protease that cleaves fibrinogen into fibrin. Other functions include activation of endothelium to generate tPA, NO, PGI2, and PDGF mediators.
RBC synthesis takes how many days
Treatment monitored with PT
Bilirubin is conjugated with glucuronic acid in this organ
Deficiency in this receptor results in Glanzmann thrombastenia
Process that breaks down the clot and has enzymatic activity of plasmin to break down fibrin and interfere with its polymerization
Unconjugated bilirubin is transported through the blood with this protein
Where does heme synthesis occur?
O allele codes for the inactive form of this enzyme
Exposed when the vessel has a lesion. GPIb binds to this.
Endothelial injury, abnormal blood flow, and hypercoagulability make up________________ triad
Reduced heme in a linear chain and is green in color
A presence of this protein means the person is Rh+
Takes up RBC after 120 days
Intrinsic or Extrinsic: Most physiologically relevant in driving coagulation after vascular damage.
Neonatal jaundice has low activity of this hepatic enzyme, which reaches adult level in 4 weeks.
A fetus synthesizes heme in this organ
20X Bilirubin levels that goes to lipid membranes and accumulate in basal ganglia result into this neurological disorder in neonates.
Treatment monitored with APTT
A or B: Galactose
Ratio of the patient's PT to the mean PT for a group of normal patients
Deficiency in GPIb results into this syndrome
Fetal blood gets in touch with the mother's blood when this detaches.
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Created Nov 21, 2010ReportNominate

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