Science Quiz / Antibiotics I and II

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Can you name the Antibiotics I and II ?

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Macrolide that does not inhibit P450 and has once daily dosing because its half life is 2-4 days.
Decreases the renal tubular secretion of penicillin
Broad spectrum antibiotic that reversibly binds to 30s ribosome and causes damage on teeth and bone and LIVER TOXICITY
4th Generation Cephalosporin that is active against Haempophilus and Neisseria
Nephrotoxicity, Ototoxicity, and Red Man Syndrome are toxicities of what drug?
Broad spectrum antibiotic that is active against aerobic and anaerobic G+ and G- bacteria. Its side effects include aplastic anemia and grey baby syndrome
Broad spectrum antibiotic specially against ANAEROBES. It binds to 23s of 50s subunit. It is recommended for phophylaxis of endocarditis when patients are undergoing dental procedu
Common Side effect of Oxacillin and Erythromycin
Aminoglycoside that can be used to treat Pseudomonas aeruginosa.
Structural analog of D-alanine and used as a 2nd line drug for TB. Adverse reaction is CNS toxicities.
Side effect of Naficllin
Penicillinase resistant penicillin that is used for endocarditis and excreted by bile.
Extended spectrum penicillin used to treat Pseudomonas aeruginosa
Macrolide, Clindamycin, Chloramphenicol, Streptogramin, and Oxazolidinones inhibit what subunit of the ribosome
Gold Standard Penicillin that is administered IV
Side effect of ampicillin and amoxicillin
Carbepenem drug that is inactivated by renal dehydropeptidases and active against G- and G+ bacteria
Semi-synthetic 14 membered ring macrolide that many macrolide resistant pathogens are susceptible to. It is used for treatment of respiratory infections and toxicity includes SEVER
Binds and inhibits 50s ribosomal subunit and effective against G+ organsims. Bacteriostatic by itself.
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Active against bacteria resistant to Gentamicin or Tobramycin
Broad spectrum antibiotic that can treat mycoplasma pneumoniae, chlamydia, rickettsiae, spirochetes, and severe acne.
2nd Generation Cephalosporin active against Anaerobes
Bactericidal antibiotic that inhibits bacterial synthesis by irreversibly binding to 30s ribosome and cause codon misreading of mRNA. It is active against G+ and G- bacteria and ha
D-Ala D-Ala Structural Analog that covalently binds to transpeptidase
1st generation Cephalosporins that are used for surgical prophylaxis
Type of drug that has the suffix 'micin' or 'mycin'
Only 2nd Generation Cephalosporin that has good CNS penetration
Side effects of this drug include diarrhea and colitis due to Clostridium Difficile
Cell Wall synthesis inhibitor active against G+ and G- that inhibits enol pyruvate
Tetracycline and Aminoglycoside inhibit what subunit of the ribosome
Aminoglycoside that has EXTREME NEPHROTOXICITY
Recommended for prophylaxis of endocarditis in patients with valvular heart disease who are undergoing dental procedures.
Most often used Aminoglycoside. Can be used with vancomycin to treat acute bacterial endocarditis
Non Beta-Lactam antibiotic that inhibits cell wall synthesis and inhibits Transglycosylase
Topical non Beta-lactam cell wall synthesis inhibitor that inhibits late stage of cell wall synthesis. It is active against G+ organims
Alternative agent for treating meningitis in patients who are allergic to penicillin. It is also used as a topical treatment for eye infections.
Cell wall synthesis inhibitor that is a cyclic lipopeptide antibiotic active against G+ only and binds to and depolarize cell membrane to cause postassium efflux and cell death

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Created Nov 2, 2010ReportNominate
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