Science Quiz / First Aid Exotoxins

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Can you name the First Aid Exotoxins

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Overactivates adenylate cyclase (Inc cAMP)
Inactivate elongation factor (EF-2)
Induces actin depolymerization, causing mucosal cell death->bowel wall necrosis and pseudomembrane formation
Inactivate 60S ribosome by cleaving RNA, cell invades
Bring MHCII & TCR in proximity to cause overwhelming IFN-y and IL-2
Protein that degrades cell membrane
Inactivate 60S ribosome by cleaving RNA, no invasion
Overactives adenylate cyclase by disabling Gi
Overactivate guanylate cyclase (Inc cGMP)
Cleave SNARE protein, inhibit neurotransmitter release; GABA and glycine
Mimics adenylate cyclase (Inc cAMP)
Zinc-dependent protease, induces apoptosis
Phospholipase that degrades tissue, cell membranes
Cleave SNARE protein, inhibit neurotransmitter release; Ach
Overatctivates adenylate cyclase by permanently activating Gs
Recruits & activates PMNs->cytokine release->mucosal damage

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