Science Quiz / First Aid Exotoxins

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Can you name the First Aid Exotoxins

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Score 0/16 Timer 10:00
MechanismOrganismManifestation
Mimics adenylate cyclase (Inc cAMP)
Inactivate elongation factor (EF-2)
Cleave SNARE protein, inhibit neurotransmitter release; Ach
Overactivates adenylate cyclase (Inc cAMP)
Overactives adenylate cyclase by disabling Gi
Recruits & activates PMNs->cytokine release->mucosal damage
Inactivate 60S ribosome by cleaving RNA, cell invades
Zinc-dependent protease, induces apoptosis
MechanismOrganismManifestation
Overactivate guanylate cyclase (Inc cGMP)
Inactivate 60S ribosome by cleaving RNA, no invasion
Overatctivates adenylate cyclase by permanently activating Gs
Induces actin depolymerization, causing mucosal cell death->bowel wall necrosis and pseudomembrane formation
Phospholipase that degrades tissue, cell membranes
Cleave SNARE protein, inhibit neurotransmitter release; GABA and glycine
Protein that degrades cell membrane
Bring MHCII & TCR in proximity to cause overwhelming IFN-y and IL-2

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