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Science Quiz / Pharmacokinetics

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Can you name the Pharmacokinetics?

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questionhint
lipophilic drug given SQ or IM is absorbed quickly or slowly?
drug that occupies the receptor sand produces no cellular effectite
passive diffusion is from high to low concentration, T or F
does dehydration cause increased or decreased volume of distribution
drugs that combine with other ions or compounds to produce an effect
if more than one drug starts to compete for binding sites on protein does the amount of free drug increase or decrease?
Cat livers have increased or decreased ability to biotransform drugs
body's ability to change the original drug into a form that can be eliminated
hydrophilic molecules dissolve in ____
most abundant protein in the blood
the random movement of drug molecules
a special 'carrier molecule' in the cell membrane moves the drug across the membrane
what removes foreign substances and toxins from the blood?
hydrophilic drug given SQ or IM is absorbed quickly or slowly?
what type of drugs move into the bloodstream by moving between capillary endothelial cells
the movement of blood from the blood stream into tissues is _____
factor that influences blood levels of a drug: rate and ____ of excretion
endothelial cells in the brain are coated with ___ cells
does passive diffusion require energy?
the time, after certain number of doses, where the peak and trough concentrations remain the same
does physical transport require energy?
biotransformation occurs primarily in what organ?
questionhint
alkaline drugs are primarily in nonionized form in _____ environment
If a molecule changes to primarily hydrophilic form, it may not be able to leave the cell; what is this called?
factor that influences blood levels of a drug: ____ of absorption
the dose of highly protein-bound drugs should be _____ if diseases are present that cause low plasma protein levels
if a drug is highly protein bound, is there more or less drug free to exert a therapeutic effect?
factor that influences blood levels of a drug: _____ of drug absorbed
facilitated diffusion is from high to low concentration, T or F
are solids or liquids more rapidly absorbed?
cell eating
does active transport require energy?
what type of drugs pass through the cell membranes?
T or F: different compartments of the body have different pHs
tablets, granules, or powders cannot be absorbed until they _______ into smaller particles
lipophilic drugs are absorbed best _____
cell drinking
altered form of a drugusually inactive
low plasma protein= more or less of drug free?
sustained-release tablets dissolve fast or slow?
most drugs given orally are absorbed in the _____
lipophilic molecules dissolve in ____
measure of the acidity or alkalinity of the drugs environment
a protein molecule in or on the cell that binds specific drugs to produce an effect, they will then determine which tissue will respond to the drug
questionhint
T or F: drug molecules can change from ionized to non-ionized or vice versa as they move to different compartments
pH where drug molecules are half ionized and half non-ionized
steady state= __ x half life
factor that influences blood levels of a drug: _____ of drug in body
What makes it hard for drug molecules to get through to the brain?
some drugs bind to large _____ in the bloodstream
is physical transport useful for large or small molecules?
drug molecules are surrounded by part of the cell membrane and taken within the cell
amount of drug that actually reaches the bloodstream
active transport is from high to low concentration, T or F
endothelial cells in the brain have ____ junctions
does ascites cause increased or decreased volume of distribution
does facilitated diffusion require energy?
drugs move most rapidly and in greater concentrations to compartments with good ____ perfusion
molecules having a net positive or negative charge are ____
drug that occupies a receptor site producing a cellular effect
a special 'carrier molecule' in the cell membrane HELPS move certain drug molecules across the membranecarrier helps, does not move molecule actively
putting drugs in oil slows absorption, this is a ____
factor that influences blood levels of a drug: drug _____ or breakdown
drug concentrations decrease by half at repeatable time intervals, this time is what?
acidic drugs are primarily in nonionized form in _____ environment
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Created Feb 8, 2011ReportFavoriteNominate

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