Science Quiz / Neuropharmacology

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QUIZ: Can you name the drugs matching each description?

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DescriptionDrugNeurotransmitter involved
Name a depolarizing neuromuscular blocking agent - this drug will cause muscle contraction before preventing itAcetylcholine
This drug works on Alzheimer's by blocking NMDA channels to prevent excitotoxicity.Glutamate
Name a drug used as a smoking cessation aid that acts as a partial agonist of the receptor usually activated by smokingAcetylcholine
Name the beta-2 receptor agonist most often found in inhalers prescribed for asthmaMostly Epinephrine
This is an anticholinesterase used to treat Alzheimer's disease (two correct answers; enter either one)Acetycholine
Name an endogenous neurotransmitter that has unspecific effects that can be used in the treatment of shockNot giving it away here...
Name a plant or its synthetic preparation that has seen increased legal use recently for such conditions as nausea associated with chemotherapy and AIDS-related wastingCannabinoids
Name one of two drugs used to treat migraines that act as 5-HT 1B,1D receptor agonists to inhibit serotonin, glutamate, and CGRP releaseSerotonin, Glutamate
Name one of the two hallucinogenic compounds found in mushrooms, both 5-HT 2 receptor agonistsSerotonin
Name a nerve gasAcetylcholine
Name an acetylcholinesterase reactivator used to treat nerve gas poisoning in the peripheryAcetylcholine
Name the insecticide that is the major cause of chronic organophosphate poisoningAcetylcholine
Name a non-addictive drug for treating ADHD that works primarily on NE rather than on DANorepinephrine
Name one of the non-depolarizing neuromuscular blocking agentsAcetylcholine
Name the endogenous adrenergic receptor agonist that is used to treat anaphylactic shockThat would be giving it away, now wouldn't it?
Name a synthetic hallucinogen affecting 5-HT 2 receptors as well as 5-HT 1 a receptors, the properties of which were discovered by accident after it was synthesized in a labSerotonin
Name either of two beta-2 receptor agonists used to relax smooth muscle and inhibit mast cell degranulationMostly Epinephrine
Name one of two drugs used to treat obesity by increasing extracellular DA and NE in the hypothalamusDopamine, Norepinephrine
Name one of the beta-1 receptor antagonists intended to depress heart rate, cardiac output, and conduction through the AV nodeEpinephrine, Norepinephrine
This drug treats ADHD by incresing DA in the synaptic cleft (as well as NE, but to a lesser degree), but is generally abused for concentration, not euphoriaDopamine, Norepinephrine
Name one of the two muscarinic receptor antagonists used to treat organophosphate poisoningAcetylcholine
DescriptionDrugNeurotransmitter involved
Name an MAO-A/B inhibitor used to treat depression that increases all extracellular monoamines in the CNSDopamine, Norepinephrine, Serotonin
Name one of the NE transport inhibitors that increases NE in the synpatic cleft to treat depression and neuropathic painNorepinephrine
Name an addictive drug that increases Dopamine, Norepinephrine, and Serotonin equally in the synaptic cleftDopamine, Norepinephrine, Serotonin
This is the only truly reversible anticholinesterase - it is used to diagnose myasthenia gravis.Acetylcholine
Name one of two drugs that can treat ADHD by increasing both DA and NE in the synaptic cleft but are a second choice for treatment because of their addictive propertiesDopamine, Norepinephrine
Used to treat Belladonna poisoning, this anticholinesterase is active in the CNS. Acetycholine
Name one of the alpha-1 adrenergic receptor agonists that causes vasoconstrictionEpinephrine, Norepinephrine
Name a drug that can be a toxin in the presence of an MAO-I because of its increase of NE through heteroexchangeNorepinephrine
Name an anti-emetic that works as an antagonist of 5-HT 3 channelsSerotonin
This drug of abuse, first studied for couples therapy for inducing feelings of empathy and often associated with raves, drastically increases serotonin levelsSerotonin
This smoking cessation aid actually is a weak antagonist of the receptor in question but also inhibits dopamine transportAcetylcholine, Dopamine
Name the 5-HT 2 agonist with the shortest half-life, otherwise known as the 'businessman's special'Serotonin
Name an alpha-1 receptor antagonist used to treat BPHEpinephrine, Norepinephrine
Name an alpha-2 receptor agonist used to treat opiate withdrawal with the intention of depressing activity of neurons controlling the SNSEpinephrine, Norepinephrine
Name a combination alpha-1/beta-1/beta-2 receptor antagonist that depresses HR and decreases CO, AV node conduction, peripheral resistance, and cardiac remodelingEpinephrine, Norepinephrine
Name the drug that is an agonist for one type of acetylcholine channels and is a powerful releasor of dopamineAcetylcholine
Name a hallucinogen more likely to be used in the Southwest because it is derived from the peyote cactusSerotonin
Name a favorite drug of overworked medical students that blocks adenosine inhibition of excitatory transmission in the CNSAdenosine
Name either of the muscarinic receptor antagonists used to prevent excessive contraction of the detrusor, relieving the symptoms of overactive bladder syndromeAcetylcholine
Name the drug used to end the action of non-depolarizing neuromuscular blocking agents by preventing ACh hydrolysis in the peripheryAcetylcholine
Name a drug used to treat obesity by inhibiting lipase to prevent digestion of ingested fats--

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