Science Quiz / I've Got You Under My Skin

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Answer these questions or name the terms related to integumentary pathology in veterinary species.

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Excessive melanin within epidermal cells due to hyperactivity of melanocytes
Faulty and/or premature cornification of epidermal cells, usually out of the normal differentiation sequence
______ are multiple crusts piled on top of one another, suggesting repetitive bouts of inflammation.
A narrow space of dermis beneath the epidermis prominently separating it from an underlying dermal lesion, often seen with mast cell tumors and lymphomas
Intracellular edema with increased pallor of injured epidermal cells as they accumulate water
Dried exudate made of serum, keratin flakes, and eosinophils and mixed with stratum corneum is known as a/n ________
Loss of cohesions between epidermal cells usually resulting in clefts, vesicles, and bullae
A small, solid elevated piece of skin
Is myxedema seen with hyper- or hypothyroidism?
A nipple-like lesion characterized by finger-like fronds of skin due to upward extension/expansion of BOTH epidermis AND dermis
A vesicle >5 cm in diameter
Grossly visible accumulations of fragments of cornified epithelium
A defect due to partial loss of the epidermis with the basement membrane remaining intact
A dilated follicular infundibulum filled with layers of sloughed, cornified epithelial cells mixed with sebum
Deposition of densely-packed collagen fibers usually parallel to the epidermal surface
Accumulation of ground substance rich in hyaluronic acid
Does exocytosis suggest that the causative agent is deep in the tissue or on the surface?
A vertical defect in the skin that extends through the epidermis into the dermis
A vertical defect in the skin that only extends through the epidermis
A small, fluid-filled cavity within the epidermis or directly beneath the epidermis
HintAnswer
A raised lesion with central pallor and an irregular darker border
Slit-like spaces within the epidermis that run parallel to the dermal-epidermal junction, often the result of acantholysis
What type of hyperkeratosis is characterized by excessive cells that have cornified completely and that lack nuclei?
Loss of melanin from epithelial cells, with accumulation of partially degraded melanin pigment in melanophages
A spot or flat discoloration of skin up to 1 cm in diameter
Increased thickness of non-cornified epithelial layers
A vesicle/bulla filled with neutrophils or eosinophils
Do collagen fibers mineralize with hyper- or hypoadrenocorticism?
A defect due to complete loss of the epidermis, breaching the basement membrane and some degree of dermal loss is known as ______
A thickened, hairless plaque of epidermis associated with persistent low-grade trauma or pressure
A macule larger than 1 cm in diameter
A sac lined by epithelium and containing fluid
A round, solid, elevated lesion >1 cm in diameter, extending deeply into the skin that results from 3D expansion of a papule
Which layer of skin is thickened in a scale?
What type of hyperkeratosis is characterized by retention of nuclei in the cornified cells, reflecting incomplete keratinization?
Migration of inflammatory cells through the epidermis
Intercellular edema that separates epidermal cells so that they are in contact with each other only at the intercellular bridges
Increased thickness of the cornified layer of the epidermis
Scales/crusts arranged in circular, spreading patches, most often associated with Staphylococcal hypersensitivity are known as _________-
A flat, solid, elevated lesion similar to a papule but larger that is oriented horizontally rather than vertically

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