| Hint | Answer |
|---|
| Abdominal pain, ascites, hepatomegaly | |
| Achilles tendon santhoma | |
| Adrenal hemorrhage hypotenion, DIC | |
| Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints | |
| Athlete with polycythemia | |
| Back pain, fever, night sweats, weight loss | |
| Bilateral hilar adenopathy, uveitis | |
| Blue sclera | |
| Bluish line on gingiva | |
| Bone pain, bone enlargement, arthritis | |
| Bounding pulses, diastolic heart murmur, head bobbing | |
| 'Butterfly' facial rash and Raynaud's phenomenon in a young female | |
| Café-au-lait spots, Lisch nodules (iris hamartoma) | |
| Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities | |
| Calf pseudohypertrophy | |
| 'Cherry-red spot' on macula | |
| Chest pain on exertion | |
| Chest pain, pericardial effusion/friction rub, persistent fever following MI | |
| Child uses arms to stand up from squat | |
| Child with fever later develops red rash on face that spreads to body | |
| Chorea, dementia, caudate degeneration | |
| Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria | |
| Cold intolerance | |
| Conjugate lateral gaze palsy, horizontal diplopia | |
| Continuous 'machinery' heart murmur | |
| Cutaneous/dermal edema due to connective tissue deposition | |
| Dark purple skin/mouth nodules | |
| Deep, labored breathing/hyperventilation | |
| Dermatitis, dementia, diarrhea | |
| Dilated cardiomyopathy, edema, alcoholism or mulnutrition | |
| Dog or cat bite resulting in infection | |
| Dry eyes, dry mouth, arthritis | |
| Dysphagia (esophageal webs), glossitis, iron deficiency anemia | |
| Elastic skin, hyper mobility of joints | |
| Enlarged, hard left supraclavicular node | |
| Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells | |
| Facial muscle spasm upon tapping | |
| Fat, female, forty, and fertile | |
| Fever, chills, headache, myalgia following antibiotic treatment for syphillis | |
| Fever, cough, conjunctivitis, coryza, diffuse rash | |
| | Hint | Answer |
|---|
| Fever, night sweats, weight loss | |
| Fibrous plaques in soft tissue of penis | |
| Gout, mental retardation, self-mutilating behavior in a boy | |
| Green-yellow rings around peripheral cornea | |
| Hamartomatous GI polyps, hyper pigmentation of mouth/feet/hands | |
| Hepatosplenomegaly, osteoporosis, neurologic symptoms | |
| Hereditary nephritis, sensorineural hearing loss, cataracts | |
| Hyperphagia, hypersexuality, hypoerorality, hyperdocility | |
| Hyperreflexia, hypertonia, Babinski sign present | |
| Hyporeflexia, hypotonia, atrophy, fasciculations | |
| Hypoxemia, polycythemia, hypercapnia | |
| Indurated, ulcerated genital lesion | |
| Infant with cleft lip/palate, microcephaly or holoprosencephaly, polydactyly, cutis aplasia | |
| Infant with failure to thrive, hepatosplenomegaly, and neurodegeneration | |
| Infant with hypoglycemia, failure to thrive, and hepatomegaly | |
| Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart defect | |
| Jaundice, palpable distended non-tender gallbladder | |
| Large rash with bull's-eye appearance | |
| Lucid interval after traumatic brain injury | |
| Male child, recurrent infections, no mature B cells | |
| Mucosal bleeding and prolonged bleeding time | |
| Muffled heart sounds, distended neck veins, hypotension | |
| Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth | |
| Myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance | |
| Neonate with arm paralysis following difficult birth | |
| No lactation postpartum, absent menstruation, cold intolerance | |
| Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia | |
| Oscillating slow/fast breathing | |
| Painful blue fingers/toes, hemolytic anemia | |
| Painful, pale, cold fingers/toes | |
| Painful, raised red lesions on pad of fingers/toes | |
| Painless erythematous lesions on palms and soles | |
| Painless jaundice | |
| Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria | |
| Pancreatic, pituitary, parathyroid tumors | |
| Periorbital and/or peripheral edema, proteinuria, hypoalbuminemia, hypercholesterolemia | |
| Pink complexion, dyspnea, hyperventilation | |
| Polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances, hypophosphatemic rickets | |
| Positive anterior 'drawer sign' | |
| Pruritic, purple, polygonal planar papules and plaques (6 P's) | |
| | Hint | Answer |
|---|
| Ptosis, miosis, anhidrosis | |
| Pupil accommodates but doesn't react | |
| Rapidly progressive leg weakness that ascends following GI/upper respiratory infection | |
| Rash on palms and soles | |
| Recurrent colds, unusual eczema, high serum IgE | |
| Red 'currant jelly' sputum in alcoholic or diabetic patients | |
| Red 'currant jelly' stools | |
| Red, itchy, swollen rash of nipple/areola | |
| Red urine in the morning, fragile RBCs | |
| Renal cell carcinoma (bilateral), hemangioblastomas, angiomatosis, pheochromocytoma | |
| Resting tremor, rigidity, akinesia, postural instability | |
| Retinal hemorrhages with pale centers | |
| Severe jaundice in neonate | |
| Severe RLQ pain with palpation of LLQ | |
| Severe RLQ pain with rebound tenderness | |
| Short stature, ↑ incidence of tumors/leukemia, aplastic anemia | |
| Single palmar crease | |
| Situs inversus, chronic sinusitis, bronchiectasis, infertility | |
| Skin hyperpigmentation, hypotension, fatigue | |
| Slow, progressive muscle weakness in boys | |
| Small, irregular red spots on buccal/lingual mucosa with blue-white centers | |
| Smooth, flat, moist, painless white lesions on genitals | |
| Splinter hemorrhages in fingernails | |
| 'Strawberry tongue' | |
| Streak ovaries, congenital heart disease, horseshoe kidney, cystic hygroma at birth, short stature, webbed neck, lymphedema | |
| Sudden swollen/painful big toe joint/ tophi | |
| Swollen gums, mucosal bleeding, poor wound healing, spots on skin | |
| Swollen, hard, painful finger joints | |
| Systolic ejection murmur (crescendo-decrescendo) | |
| Thyroid and parathyroid tumors, pheochromocytoma | |
| Thyroid tumors, pheochromocytoma, ganglioneuromatosis | |
| Toe extension/fanning upon plantar scrape | |
| Unilateral facial drooping involving forehead | |
| Urethritis conjunctivitis, arthritis in a male | |
| Vascular birthmark (port-wine stain) | |
| Vomiting blood following gastroesophageal lacerations | |
| Weight loss, diarrhea, arthritis, fever, adenopathy | |
| 'Worst headache of my life' | |
|
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