Hint | Answer |
Abdominal pain, ascites, hepatomegaly | |
Achilles tendon santhoma | |
Adrenal hemorrhage hypotenion, DIC | |
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints | |
Athlete with polycythemia | |
Back pain, fever, night sweats, weight loss | |
Bilateral hilar adenopathy, uveitis | |
Blue sclera | |
Bluish line on gingiva | |
Bone pain, bone enlargement, arthritis | |
Bounding pulses, diastolic heart murmur, head bobbing | |
'Butterfly' facial rash and Raynaud's phenomenon in a young female | |
Café-au-lait spots, Lisch nodules (iris hamartoma) | |
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities | |
Calf pseudohypertrophy | |
'Cherry-red spot' on macula | |
Chest pain on exertion | |
Chest pain, pericardial effusion/friction rub, persistent fever following MI | |
Child uses arms to stand up from squat | |
Child with fever later develops red rash on face that spreads to body | |
Chorea, dementia, caudate degeneration | |
Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria | |
Cold intolerance | |
Conjugate lateral gaze palsy, horizontal diplopia | |
Continuous 'machinery' heart murmur | |
Cutaneous/dermal edema due to connective tissue deposition | |
Dark purple skin/mouth nodules | |
Deep, labored breathing/hyperventilation | |
Dermatitis, dementia, diarrhea | |
Dilated cardiomyopathy, edema, alcoholism or mulnutrition | |
Dog or cat bite resulting in infection | |
Dry eyes, dry mouth, arthritis | |
Dysphagia (esophageal webs), glossitis, iron deficiency anemia | |
Elastic skin, hyper mobility of joints | |
Enlarged, hard left supraclavicular node | |
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells | |
Facial muscle spasm upon tapping | |
Fat, female, forty, and fertile | |
Fever, chills, headache, myalgia following antibiotic treatment for syphillis | |
Fever, cough, conjunctivitis, coryza, diffuse rash | |
| Hint | Answer |
Fever, night sweats, weight loss | |
Fibrous plaques in soft tissue of penis | |
Gout, mental retardation, self-mutilating behavior in a boy | |
Green-yellow rings around peripheral cornea | |
Hamartomatous GI polyps, hyper pigmentation of mouth/feet/hands | |
Hepatosplenomegaly, osteoporosis, neurologic symptoms | |
Hereditary nephritis, sensorineural hearing loss, cataracts | |
Hyperphagia, hypersexuality, hypoerorality, hyperdocility | |
Hyperreflexia, hypertonia, Babinski sign present | |
Hyporeflexia, hypotonia, atrophy, fasciculations | |
Hypoxemia, polycythemia, hypercapnia | |
Indurated, ulcerated genital lesion | |
Infant with cleft lip/palate, microcephaly or holoprosencephaly, polydactyly, cutis aplasia | |
Infant with failure to thrive, hepatosplenomegaly, and neurodegeneration | |
Infant with hypoglycemia, failure to thrive, and hepatomegaly | |
Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart defect | |
Jaundice, palpable distended non-tender gallbladder | |
Large rash with bull's-eye appearance | |
Lucid interval after traumatic brain injury | |
Male child, recurrent infections, no mature B cells | |
Mucosal bleeding and prolonged bleeding time | |
Muffled heart sounds, distended neck veins, hypotension | |
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth | |
Myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance | |
Neonate with arm paralysis following difficult birth | |
No lactation postpartum, absent menstruation, cold intolerance | |
Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia | |
Oscillating slow/fast breathing | |
Painful blue fingers/toes, hemolytic anemia | |
Painful, pale, cold fingers/toes | |
Painful, raised red lesions on pad of fingers/toes | |
Painless erythematous lesions on palms and soles | |
Painless jaundice | |
Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria | |
Pancreatic, pituitary, parathyroid tumors | |
Periorbital and/or peripheral edema, proteinuria, hypoalbuminemia, hypercholesterolemia | |
Pink complexion, dyspnea, hyperventilation | |
Polyuria, renal tubular acidosis type II, growth failure, electrolyte imbalances, hypophosphatemic rickets | |
Positive anterior 'drawer sign' | |
Pruritic, purple, polygonal planar papules and plaques (6 P's) | |
| Hint | Answer |
Ptosis, miosis, anhidrosis | |
Pupil accommodates but doesn't react | |
Rapidly progressive leg weakness that ascends following GI/upper respiratory infection | |
Rash on palms and soles | |
Recurrent colds, unusual eczema, high serum IgE | |
Red 'currant jelly' sputum in alcoholic or diabetic patients | |
Red 'currant jelly' stools | |
Red, itchy, swollen rash of nipple/areola | |
Red urine in the morning, fragile RBCs | |
Renal cell carcinoma (bilateral), hemangioblastomas, angiomatosis, pheochromocytoma | |
Resting tremor, rigidity, akinesia, postural instability | |
Retinal hemorrhages with pale centers | |
Severe jaundice in neonate | |
Severe RLQ pain with palpation of LLQ | |
Severe RLQ pain with rebound tenderness | |
Short stature, ↑ incidence of tumors/leukemia, aplastic anemia | |
Single palmar crease | |
Situs inversus, chronic sinusitis, bronchiectasis, infertility | |
Skin hyperpigmentation, hypotension, fatigue | |
Slow, progressive muscle weakness in boys | |
Small, irregular red spots on buccal/lingual mucosa with blue-white centers | |
Smooth, flat, moist, painless white lesions on genitals | |
Splinter hemorrhages in fingernails | |
'Strawberry tongue' | |
Streak ovaries, congenital heart disease, horseshoe kidney, cystic hygroma at birth, short stature, webbed neck, lymphedema | |
Sudden swollen/painful big toe joint/ tophi | |
Swollen gums, mucosal bleeding, poor wound healing, spots on skin | |
Swollen, hard, painful finger joints | |
Systolic ejection murmur (crescendo-decrescendo) | |
Thyroid and parathyroid tumors, pheochromocytoma | |
Thyroid tumors, pheochromocytoma, ganglioneuromatosis | |
Toe extension/fanning upon plantar scrape | |
Unilateral facial drooping involving forehead | |
Urethritis conjunctivitis, arthritis in a male | |
Vascular birthmark (port-wine stain) | |
Vomiting blood following gastroesophageal lacerations | |
Weight loss, diarrhea, arthritis, fever, adenopathy | |
'Worst headache of my life' | |
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