more common and consist of a gylcerol backbone to which are attached two fatty acids
sheet-like encolsed structures consisting of an assymetric lipid bilayer w/ inner and outer surfaces
total free energy values for transferring successive sequences of 20 AA
Vesicles surrounded by a lipid bilayer with an acqeous interior
type of protein that interact extensively with phospholipids and require detergents for their solubilization
cytoskeletal structure within erythrocyte bound to ankyrin; maintenance of biconcave shaoe of RBC
exist that transfer certain phopholipids to inner to outer leaflet
recognize specific phopholipids and transfer from one menbrane to ER to others (mitochondrial / peroxisomal)
phospholipid that contains sphingosine rather than a glycerol backbone
major phosphoglyceride by mass in human cells
sugar containing lipids built on backbone of ceramide
most common sterol in the membranes of animal cells
T or F the more unsaturated tha FA the lesser the kink
In a solvent such as water phospholipids spontaneously organize themselves into______
T or F many drugs are hydrophilic and can readily cross membranes
Question
Answer
acts as a solvent for membrane proteins
Process wherein some proteins are anchored to one leaflet of the bilayer by covalent linkages to certain lipids
transverse movement of lipids across the membrane
major inorganic anion in ICF
key intermediate in the formation of other phosphoglycerides
Exist as sheets wherein the hydrophobic regions of the phospholipids are sequestered from acqeous environment
Lipids and certain proteins exhibit this movement in the plane of their membrane and many do not exhibit this because nonmobile proteins are anchored to the underlying actin cytosk
Endoplasmic Reticulum enzymatic markers
Inner mitochondrial membrane enzymatic markers
Acts a buffer to modify the fluidity of membranes
Often located below the apical surface of epithelial cellscand prevent the diffusion of macromolecules between cells
Specialized areas of the exosplasmic (outer) leaflet of the lipid bilayer enriched in cholesterol, sphingolipids, and certain proteins ;involved in signal transduction
bound to the inner aspect of the integral protein ‘band 3’ of the erythrocyte membrane
Span the membrane ONLY ONCE
Do not interact directly with the hydrophobic cores of the phospholipids in the bilayer
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