Science Quiz / SCCP 607 Dosage Forms and Drug Delivery Systems Exam Guide 1

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Can you name the SCCP 607 Dosage Forms and Drug Delivery Systems Exam Guide 1?

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Definition/HintAnswer
lactose, calcium carbonate, magnesium carbonate, calcium phosphate, and pre-gelatined starch are all examples of
The processing of drug molecules by enzymes
Drug delivery system
ADME stands for:
Algynate, cross-linked PVP, microcrystalline cellulose are all examples of
Inhaled, opthalmic, and oral dosage forms are all examples of routes of _____
the loss of water (or a solvent) of crystallization from a hydrated or solvated salt to the atmosphere on exposure to air
True or False: The Noyes-Whitney Equation helps explain why powders are more readily dissolved, and therefore absorbed, than tablets
Renal, lactation, defacation, entero hepatic shunt, pulmonary are pathways of _______
Act as adhesive to ‘bind together’ powders, granules and tablets to result in the necessary mechanical strength
Sensitivity Requirement/tolerable % error
Enzymes that are induced by alcohol and play a large role in the metabolism of drugs
the escape of gas from an aqueous solution and the foaming or fizzing that results from a release of the gas.
rub to pieces; continuous rubbing/grinding of the powder in a mortar with a pestle; used when working with hard, fracturable powders
Sugar, film, enteric, fluid bed, air suspension are all forms of what
Start with substance in smallest amount, add ingredient with next larger quantity
process of reducing particle size for more uniform distribution of particle sizes
As a pharmacist, you just compounded a formulation containing a manufactured drug and water. How long will the Beyond Use Date be?
Definition/HintAnswer
Help deaggregate tablets; Deforms tablets upon contact with water
Magnesium stearate, egstearic acid, sodium stearyl fumarate, sodium behenate are all examples of
pregelatinized starch, microcrystalline cellulose, sodium bicarbonate, alginic acid are examples of
relative strengths of 2 medications that produce the same effect
% of patients who get a specific effect from a drug
The more uniform the size of particles, the more uniform the _______ rate
Used as bulking agents/filler
Name of Equation: pH = pKa + log([A-]/[HA])
to make smooth; reducing particle size in a mortar or spatulating it on an ointment slab or pad with a small amount of liquid in which the solid is not soluble
The movement of a drug from the bloodstream into various tissues
The movement of a drug from administration site into the bloodstream
discourages foam formation by lowering surface tension and cohesive binding of the liquid phase
colloidal silicon dioxide (talc) is an example of a
It is recommended that a dose for a drug will be 5mg/kg/dose. If a male patient is 5'9”, ideally, how many milligrams will one dose be?
Prevent adherence of granule/powder to punch die/faces and promote smooth ejection from the die after compaction
amount of drug in a given dosage form
An agent intended for use in the diagnosis, treatment, cure or prevention of disease in humans or other animals
Improve particle flow by adhering to particles, reducing inter‐particulate friction

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