Science Quiz / SCCP 607 Dosage Forms and Drug Delivery Systems Exam Guide 1

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Can you name the SCCP 607 Dosage Forms and Drug Delivery Systems Exam Guide 1?

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Definition/HintAnswer
colloidal silicon dioxide (talc) is an example of a
Act as adhesive to ‘bind together’ powders, granules and tablets to result in the necessary mechanical strength
amount of drug in a given dosage form
As a pharmacist, you just compounded a formulation containing a manufactured drug and water. How long will the Beyond Use Date be?
The movement of a drug from administration site into the bloodstream
Help deaggregate tablets; Deforms tablets upon contact with water
discourages foam formation by lowering surface tension and cohesive binding of the liquid phase
An agent intended for use in the diagnosis, treatment, cure or prevention of disease in humans or other animals
to make smooth; reducing particle size in a mortar or spatulating it on an ointment slab or pad with a small amount of liquid in which the solid is not soluble
the loss of water (or a solvent) of crystallization from a hydrated or solvated salt to the atmosphere on exposure to air
True or False: The Noyes-Whitney Equation helps explain why powders are more readily dissolved, and therefore absorbed, than tablets
Name of Equation: pH = pKa + log([A-]/[HA])
Sugar, film, enteric, fluid bed, air suspension are all forms of what
The more uniform the size of particles, the more uniform the _______ rate
pregelatinized starch, microcrystalline cellulose, sodium bicarbonate, alginic acid are examples of
Renal, lactation, defacation, entero hepatic shunt, pulmonary are pathways of _______
Magnesium stearate, egstearic acid, sodium stearyl fumarate, sodium behenate are all examples of
% of patients who get a specific effect from a drug
Definition/HintAnswer
process of reducing particle size for more uniform distribution of particle sizes
lactose, calcium carbonate, magnesium carbonate, calcium phosphate, and pre-gelatined starch are all examples of
Start with substance in smallest amount, add ingredient with next larger quantity
The processing of drug molecules by enzymes
Algynate, cross-linked PVP, microcrystalline cellulose are all examples of
ADME stands for:
the escape of gas from an aqueous solution and the foaming or fizzing that results from a release of the gas.
Enzymes that are induced by alcohol and play a large role in the metabolism of drugs
The movement of a drug from the bloodstream into various tissues
relative strengths of 2 medications that produce the same effect
Used as bulking agents/filler
Prevent adherence of granule/powder to punch die/faces and promote smooth ejection from the die after compaction
It is recommended that a dose for a drug will be 5mg/kg/dose. If a male patient is 5'9”, ideally, how many milligrams will one dose be?
Sensitivity Requirement/tolerable % error
rub to pieces; continuous rubbing/grinding of the powder in a mortar with a pestle; used when working with hard, fracturable powders
Inhaled, opthalmic, and oral dosage forms are all examples of routes of _____
Improve particle flow by adhering to particles, reducing inter‐particulate friction
Drug delivery system

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