Science Quiz / Cholesterol

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Can you name the Cholesterol?

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Apolipoprotein that mediates chylomicron secretion into lymphatics
Dyslipidemia with defective ApoE
Acts as repository for apo C & E (needed for chylomicron and VLDL metabolism). Secreted from both liver and intestine
Mediates transfer of cholesterol esters to other lipoprotein particles
Delivers hepatic TGs to peripheral tissue. Secreted by liver
Apolipoprotein that is lipoprotein lipase cofactor; catalyzes cleavage
Dyslipidemia with lipoprotein lipase or apolipoprotein C-II deficiency
Presents with acute pancreatitis
Apolipoprotein that binds LDL receptor
Apolipoprotein that mediates remnant uptake
Degradation of dietary triglycerides in small intestine
Degradation of TGs stored in adipocytes
Dyslipidemia with hepatic overproduction of VLDL
Only apolipoprotein on LDL
Degradation of TGs circulating in chylomicrons and VLDLs; found on vascular endothelial surface
Taken up by target cells via receptor-mediated endocytosis
Enzyme that catalyzes Nascent HDL --> Mature HDL
Presents with accelerated atherosclerosis, tendon xanthomas, corneal arcus
Delivers dietary TGs to peripheral tissues; delivers cholesterol to liver in form of remnants (most depleted of their TGs). Secreted by intestinal epithelial cells
Presents with creamy layer in supernatant
Degradation of TGs remaining in IDL
Formed in degradation of VLDL. Delivers TGs and cholesterol to liver
Presents with premature atherosclerosis, tuberoeruptive xanthomas, xanthoma striatum palmare
Delivers hepatic cholesterol to peripheral tissues. Formed by HL modification of IDL in liver and peripheral tissue
Dyslipidemia with absent or defective LDL receptors
Vitamin used in tx of abetalipoproteinemia?
Apolipoprotein that activates LCAT
Mediates reverse cholesterol transport from periphery to liver
Needed to maintain cell membrane integrity and synthesize bile acids, steroids, and vitamin D
Catalyzes esterification of 2/3 of plasma cholesterol

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Created Apr 30, 2017ReportFavoriteNominate

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