Science Quiz / Anticancer IV-V (Miscellaneous, Hormone, and Targeted)

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Can you name the Anticancer (Miscellaneous, Hormone, and Targeted)?

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B cell suppressor that also stop reacting to vaccines
Treatment for Non-hodgkin lymphoma
Block Mitosis by inhibiting MT polymerization
Side effects: Early and delayed onset diarrhea
ER antagonist in breasts, but partial agonist everywhere else
An adverse affect brought on by a mechanism of action intended to treat
Topoisomerase II poison
Class of drug that intercalates in DNA chain and blocs Topoisomerase II
G1 enzyme that Asparagine which is essential in some tumors but not in humans
Block Mitosis by inhibiting MT depolymerization
What enzyme does Azacitidine and Cecitabine inhibit for 3/4 replication cycles
Side effects: ROS, Cardiac Toxicity, damage to host TOP2B
Binds to GC rich DNA using iron
'-nibs'
Side effects:GI toxicity & myelosupression
HintAnswer
Topoisomerase I poison
TKIs are substrates for what clearance enzyme
What type of agonist is used to treat Prostate cancer but causes an initial LH/FSH
Similar MOA to anthracyclines produces NO2 instead of ROS
Who will have the most benefit from Tamoxifen and Aromatase Inhibitors
Side effects:Gynecomastia, breast pain
Blocks HER2/neu in breast cancer
Makes tumors more immunogenic or alters there reactions with other cells by acting on the co-repressor receptor RAR-alpha
Camptothecin that acts as reversible AchE inhibitor
Treatment for chronic myelogenous leukemia (CML)
TKI that can cause pleural or pericardial edema
Drug-drug interactions with vinca alkyloids can lead to?
An iron chelator that treats anthracycline side effects but my also disinhibit tumors
Irinotecan is induced/inhibited by what hepatic clearance phase
Side effects:ROS, Skin and Lung toxicity

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Created Nov 19, 2016ReportNominate
Tags:hormone, targeted

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