Science Quiz / PODule 5.3-5.5

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Can you name the PODule 5.3-5.5?

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How many nuclei would a giant cell typically have? How many MIGHT it have?
 
 
What are the four main causes of granulomatous inflammation?
 
 
 
 
Which cell type dominates granulomatous inflammation?
 
______ foreign bodies tend to cause granulomatous inflammation, whereas _____ ones cause suppurative reactions.
 
 
Macrophages tend to secrete ___-__ which stimulates NK cells and T cells to make _____-___, prompting the macrophages to form giant cells or epithelioid cells. (A process known as.
 
 
 
Which of the following is not a potential cause of granulomatous inflammation?
A) blastomyces dermatidis B) cryptococcus neoformans C) Johne's disease D) feline infectious peritonitis virus E) none of the above 
What kind of helper t cells are involved in granulomatous inflammation?
 
True or false: Johne's disease is a form of malabsorptive diarrhea?
 
What is the term for a discrete nodule of granulomatous inflammation, surrounded by a ring of lymphocytes and fibrous tissues?
 
What is mycobacterium avium the causative agent of?
 
What is the term for immature fibrosis and neovascularization in healing tissues?
 
What is the collective term for macrophages, dendritic cells and monocytes?
 
What chemical is only released by macrophages during their oxidative burst
 
What three types of disease are suggested by lesions dominated by plasma cells and T cells, with an absence of other leukocytes?
 
 
 
What are the two main cell types in type IV hypersensitivity reactions?
 
 
Where are cows injected during the tuberculin reaction?
 
What is it termed when an inflammatory response goes from local to systemic? What are the three primary mediators involved?
 
 
 
 
What are the most common illnesses that cause inflammatory responses to go systemic?
 
 
 
 
 
Which of the following is not an effect of the acute phase response?
A)fever B) decrease in production of acute phase proteins C)lethargy D)depression E)anorexia 
In which species are haptoglobins diagnostically useful indicators of the acute phase response? Primary function?
 
 
In which species are protease inhibitors diagnostically useful signs of the acute phase response?
 
In which species is a pentraxin a useful diagnostic indicator of the acute phase response? Which one?
 
 
What type of reaction does mycoplasma haemofelis cause? Which cells mediate this?
 
 
 
Name an example of a type II reaction which involves improper activation of a membrane receptor?
Hint, it's a human disease, so you probably don't actually care. Sorry. 
Name an example of a type II reaction which involves blocking of membrane receptors?
you actually care about this one! It might cause megaesophagus! : ( 
Name an example of a type II reaction which results in cell injury/death?
 
Ig_ would be associated with intravascular lysis, whereas Ig_ tends to prompt phagocytosis in certain areas of the body.
 
 
Transfusion reactions are most common in what type of animal?
 
Why are transfusion reactions uncommon in dogs? When might you expect them?
 
 
In which species are isoimmune hemolytic anemias or thrombocytopenias common?
 
What disease involves autoantibodies against desmocollin 1, resulting in vesicles that become pustules with neutrophilic invasion?
 
Failure of which of the following has NOT been identified as a mechanism of auto-immune disease in domestics?
A) deletion of self-recognizing lymphocytes in primary lymphoid organs B)induction of anergy C)suppressive effects of regulatory T cells D)apoptosis of lymphocytes repeatedly exposed to antigen 
What is the term for the cause of autoimmunity that involves self-antigens changing shape to expose novel epitopes?
 
Mycoplasma and mycobacteria can act as ______ by linking MHC proteins to T or B cells, activating non-specific lymphocytes.
 
Traumatic injury to the ____ or _____ may cause autoimmune disease, as these areas are normally sequestered.
 
 
What two endocrine deficiencies may have an autoimmune pathogenesis?
___ and ____ (one is also known as addison's disease) 
What would one look for as diagnostic evidence of SLE? The disease is rare in dogs, but most often affects...?
 
 
How long does it take fibrin to fill a small wound?
 
What is the removal of necrotic tissues to facilitate repair and reduce scarring referred to as?
 
I want a badass scar, for some reason. Would I prefer my lesion healed with more PDGF or TGF-beta?
 
What is the result of fibrin becoming trapped on top of epithelials migrating on top of granulation tissue lower down?
 
When does collagen I start forming in the remodelling phase? What is the peak production time?
 
 
What situations might indicate to a vet that they ought to allow a wound to heal by second intention?
 
 
Where would you most commonly see 'proud flesh' forming? What is the other name for it? What distinguishes it from other granulation tissues?
 
 
 
What type of collagen forms initially in granulation tissue, and what replaces it?
 
 

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