Just For Fun Quiz / Exam 9 Drugs

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Can you name the Exam 9 Drugs?

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Score 0/33 Timer 20:00
MechanismDrugDisease or Use
V2 receptor agonist, replace or supplement vasopressionDiabetes insipidus, nocturnal enuresis
Estrogen receptor agonist in bone and uterus, antagonist in breast and brainBreast cancer (treatment and prevention)
Growth hormone receptor antagonist, most effective therapy for normalization of IGF-1Acromegaly, gigantism
DPP-IV inhibitor; slows breakdown of GLP-1 and GIPType 2 diabetes
Short-acting KATP channel blockers, increase insulin secretionType 2 diabetes
Replace or supplement T4Hypothyroidism
Replace or supplement insulinType 1 and type 2 diabetes
GLP-1 agonist; potentiation of insulin secretion, inhibition of glucagon secretionType 2 diabetes
Activation of peroxisome proliferator-activated receptors (PPAR), increase in insulin-stimulated rate of glucose utilization, reduced lipolysis and increased fat storage, reduced cType 2 diabetes
GnRH receptor agonists, intended to block testosterone secretion through downregulation of pituitary GnRH receptorsProstate cancer
Concentration in and destruction of thyroid tissueHyperthyroidism
D2 receptor agonist/weak D1 receptor antagonist, intended to reduce the secretion of growth hormone or prolactinAcromegaly, gigantism, hyperprolactinemia
Androgen receptor antagonistProstate cancer
Cyp 17,20 lyase inhibitor, inhibit production of testosteroneProstate cancer
Androgen receptor agonistsInfertility, hypogonadism, muscle wasting/atrophy, erythropoiesis, HRT (men), endometriosis
Supplement oxytocinInitiation or improvement of uterine contractions in labor or incomplete abortion, control of postpartum bleeding
V1A,V2 receptor antagonistHyponatremia
MechanismDrugDisease or Use
Replace or supplement growth hormonePrimary growth hormone deficiency, Turner’s Syndrome, Prader-Willi syndrome, Chronic growth retarding disease, Idiopathic short stature, Chronic renal insufficiency, AIDS wasting syndrome
Alternate substrate for thyroperoxidase, inhibition of thyroxin synthesis, inhibition of coupling to form thyroglobulinHyperthyroidism (except during pregnancy and breast feeding)
Inhibition of thyroid hormone synthesis and release,Hyperthyroidism preparative to thyroidectomy, reduction of thyroid gland vascularity, reduction of thyroid cell proliferation
Somatostatin receptor agonists, intended to reduce the secretion of growth hormone in response to any stimulusAcromegaly, gigantism
Analogue of amylin (a small peptide normally released from beta cells along with insulin); slows gastric emptying, promotes satiety, inhibits glucagon secretionType 1 and type 2 diabetes
Progesterone receptor agonistsContraception, emergency contraception, endometriosis, dysfunctional uterine bleeding, hormone-refractory breast cancer, HRT (without hysterectomy)
5-α reductase inhibitors, inhibit production of dihydrotestosteroneBPH, male pattern baldness
V2 receptor antagonistHyponatremia
Replace or supplement T3Myxedema coma
Estrogen receptor agonists in bone, antagonists in breast, uterus, and brainBreast cancer (treatment and prevention), osteoporosis
Alternate substrate for thyroperoxidase, inhibition of thyroxin synthesis, inhibition of coupling to form thyroglobulin, inhibition of T4®T3Hyperthyroidism (especially during pregnancy and breast feeding)
Progesterone receptor antagonistsPregnancy termination
Estrogen receptor partial agonist in brainInfertility
Estrogen receptor agonistsContraception, infertility, prostate cancer, HRT
Decreased hepatic glucose production, potentiation of insulin action in peripheral tissues by increasing cell surface insulin receptors, increasing Glut4 glucose transporters and iType 2 diabetes
Long-acting KATP channel blocker, increases insulin secretionType 2 diabetes

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