Science Quiz / Autoimmune Pathology

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Can you name the Autoimmune Pathology?

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HintAnswer
3 symptoms with graft vs host disease
Recurrent bacterial infections associated with development of autoimmune disorders and lymphoma and gastric cancer
delayed type HSR is which type of HSR
Hep B virus antigens in some cases causing vasculitis
streptococcal cell wall antigen planted in glomeruli
complement defects can lead to what infections
monoclonal antibody against T cell antigen site
anti DNA Topoisomerase/SCL-70 antibodies
RA is which type of HSR
Type I HSR involves what cells
lupus anticoagulant can be seen with ___ and so can ___ which can creat a fake positive ___ test
clinical example of arthus reaction
autosomal recessive form of SCID is due to what deficiency
RA, SLE, and polymyositis associted with what secondary form of disease
mnemonic for digeorge syndrome
most common CNS infections with AIDS
which immunoglobulin kills parasites
acute cellular rejection is what type of HSR
hydralazine, procainamine can cause
contact dermatitis is which type of HSR
what is spared in MCTD
primary amyloidosis is prodution of too much
second signal for B cell activation
NK adhesion molecule
Chron disease is which type of HSR
MHC class I loci
hyperacute rejection is what type of HSR
HLA-B27
second signal for CD4 activation
opsonization and phagocytosis of RBCs
granuloma formations are which type of HSR
What drug can prevent acute vascular rejection by blocking IL-2 release
anemia, thrombocytopenia, and leukemia in SLE due to what HSR
HLA DR3/4
HintAnswer
hyper igm syndrome is caused by problem with
comfirm aids with
dry mouth
T-cell mediated toxicity is which type of HSR
complement mediated inflammation of BM in lungs/kidneys
no IgG in blood after 6 months
anti-Smith antibodies
hemodyalisis-associted amyloidosis is too much
HLA BW47
what deposits in type III HSR
HLA-DR2
disruption of cadherins with proteases and formation of vesicles on skin
organ rejection when patient instantly becomes hypotensive, dies
the ratio of kappa to lambda should be
asthama and drug hypersensitivity are what type of HSR
serum against what diagnoses MCTD
malar butterfly rash is what type of necrosis
test for type II HSR
anti-centrome antibodies
heart problem with SLE
what immune cell kills cells that dont display proper MHC
most common lung infection with AIDS
anti-RNP (SS-A/SS-B)
hyper-segmented neutrophils right or left shift
failure of 3rd and 4th pouch development
initial edema of skin, then ulceration, desquamation, with secondary reynauds
rash only variant of lupus
GI dysmotility, malabsorption
anti histones antibodies
you see neutrophils with big lobes with right or left ****
what is spared in drug-induced lupus
second signal for CD8 activation
nuclear antigens with nephritis, skin lesions, etc
sjogrens patients have a 40% risk of developing what malignancies
HintAnswer
AIDS defining malignancies
 
HIV entry into CD4 cells requires what 2 proteins
most common fungal infection in AIDS patients
thrombocytopenia and eczema
special heart problem with SLE
find antibody deposits at dermal-epidermal junctions
no class switching by B cell is activated
mono uses which complement receptor
X-linked form of SCID is due to no production of
MHC genes are found on chromosome
malignant hypertension from hyperplastic arteriolosclerosis can be a complication of what
nonpolymorphic beta 2 globulin is found with a polymorphic alpha chain in which molecule
main manifestation of lupus
streptococcal antigen; cross reaction with heart and macrophage activation
the ratio of CD4 to CD8 should be
maternal IgG crosses placenta and attaches to fetal RBCs
screen aids with
test for type I HSR
which immunoglobulin is found on lumen or resp/GI tracts
enlarged gland syndrome
skin manifestation of SLE
anti dsDNA antibodies point to
urticaria, eczema, hay fever, asthsma, angioedema
neutrophil degranulation
do you get deformities with arthritis
sjogrens is destruction of ___ and ___ glands
NK receptor for Fc of IgG
75% of sjogrens patients have what
localized scleroderma mnemonic
malar butterfly rash caused by what type HSR
which immunoglobulin is not produced as a free antibody
primary amyloidosis is associated with
graft vs host disease seen most with _____ transplants

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