Major depression not responsive to other drugs, Chronic pain, Enuresis
Cocaine craving + withdrawal
Neuropathic pain, MIgraines
Phobias, Anxiety, OCD
Tachycardia, Arrythhmias, precipitate in mania
Seretonin and Noadreneline reuptake inhibitor
Dopamine reuptake inhibitor
Inhibit recycling og neuronal membrane phophoinositides (decrease IP levels), 1st line maintenance of tx of Bipolar Disorder, Mania stage bipolar, Mood stabilizer
Narrow TI, Movement tremor, Nephrogenic diabetes, HypOthyroidism, Pregnancy problems (LMNOP), Polyuria/polydipsia (competes with ADH), Weight gain, Skin rash
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