Science Quiz / Touro PA Pharmacological Drugs

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Can you name the antihypertensive drugs?

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Sympatholytics
class of drugs 
class of drugs 
class of drugs 
class of drugs 
Antihypertensives
class of drugs 
class of drugs 
class of drugs 
class of drugs 
class of drugs 
Alpha 2 agonists
drug 
drug 
drug 
Cardiac Output
equation 
Blood pressure
equation 
heart failure strategy
class of drugs-contractility improvement 
class of drugs- decrease volume 
class of drugs- decrease RAAS and left ventricular hypertrophy 
class of drugs 
class of drugs 
Diuretics
drug- first line of treatment for HTN- distal convoluted tube 
loop- ascending 
loop- ascending 
loop- ascending 
potassium sparing- collecting tubule- causes gynecomastia and hyperkalemia 
ACE inhibitors
active 
active 
prodrugs- given PO and 1st activated by liver 
prodrugs- given PO and 1st activated by liver 
prodrugs- given PO and 1st activated by liver 
prodrugs- given PO and 1st activated by liver 
ARBs
drug 
drug- used most often 
drug 
drug 
vasodilators
class-works on venules. examples are sildenafil. NTG prototype 
drug- rapid reversal of BP- treat hypoglycemia 
drug- ARF- causes hypertrichosis. use with diuretic and beta blocker 
IV for HTN emergencies. arterioles and veins 
arteriolar drug- ARF- lupus like syndrome 
beta blockers
drug- no selective- drug of choice 
drug- selective- approved for CHF- cardioselective beta-1 
drug- selective- ISA- only affect HR at exercise 
no CNS depression 
drug- ISA- non selective 
beta blocker
class 2 drug- non selective-  
cardiac glycosides
decreases activity of NA-K pump- adenosine prototype 
cardiotonics
beta-1 agonist- selective 
increases cAMP by inhibiting phosphodeisterase 
cardiotonics
blocks NA/K ATPase- long term cardiac contractility 
drug 
recombinant bnp
drug 
Antiarrythmics
new addition to CHF drugs. overtime decrease SANS reflex 
Chest pain
brought on by exertion- beta blockers 
can happen at rest- vasospasms- vasodilators 
NTG no longer helps 
drug combos for angina
prevention of reflex tachycardia while reducing workload 
prevent reflex tachycardia of arteriolar only drug 
2 mechanisms to reduce heart work 
antiarrythmic drugs
class 1- ventricular arrythmias 
class 2- block NE and Epi at SA node 
class 3- torsades de pointes common adverse effects 
class 4- works on pacemakers 
sodium channel blockers
not used much anymore/doubles free level of digoxin 
blocks potassium channels prolonging refractory period/lupus like syndrome 
reduces HR the most 
IV- ventricular asystoles- supresses digoxin induced ventricular arrythmias 
IV post MI- causes cardiac depression- V fib 
effective but dangerous- last resort for ventricular arrythmias 
potassium channel blockers
class 2 and 3 actions 
A fib- IV only- requires MD bc likelihood of torsades de pointes 
A fib- monitor by measuring renal clearance 
treat ANY type of arrythmia by prolonging refractory period 
calcium channel blockers
arteriole only- decrease TPR and BP 
dipine 
dipine 
dipine 
dipine 
drug- atrial fibrilation and atrial flutter 
drug- atrial fibrilation and atrial flutter 
ace inhibitors
adverse effect 
adverse effect- bradykinin 
adverse effect 
adverse effect- aldosterone absense 
diuretics
adverse effect- sodium 
adverse effect- potassium 
adverse effect- uric acid 
adverse effect- glucose 
adverse effect- potassium sparing  
vasodilators
adverse effect- compensation of blood pressure 
adverse effect- blood pressure 
adverse effect- blood flow to areas of less resistance 

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