Science Quiz / Autacoids

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Can you name the Autacoids?

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ClassDrug (Generic)Mechanist/Uses
H1R antagonist; 5HT, a1 & MR blockmild anti-cholinergic, moderate sedative, GI side effects
Serotonin Agonists5HT 1B & 1D; migraines; constrict & prevent vasodilation and stretching of pain nerve endings, Inhibit endogenous NT (CGRP) release in perivascular space
Serotonin AgonistsGERD (withdrawn), 5HT4
H1R antagonist; 5HT, a1 & MR blockstrong sedative, anxyolytic
Serotonin AntagonistsBlocks 5HT7 & Dopamine receptors, atypical antipsychotic used in schizo. pts
Serotonin Antagonists5HT3 blocker, Prevents Nausea and Vomiting after surgery/chemotherapy MAJOR
Serotonin Antagonists5HT2a blocker, also blocks alpha adrenergic receptors, blocks USM contraction, platelet aggregation, used in Europe for hypertension, not USA
2nd generation Anti-Histamine
Serotonin Antagonists5HT2a selective antagonist, similar to Ketanserin but NO alpha activity
ClassDrug (Generic)Mechanist/Uses
Serotonin AgonistsAnxyolytic, 5HT1A agonist
2nd generation Anti-Histamine
2nd generation Anti-Histamine
H1R antagonist; 5HT, a1 & MR blockmoderate sedative, mild anti-cholinergic, 5HT2a antagonist, carcinoid syndrome, cold induced urticaria, 5HT syndrome
H1R antagonist; 5HT, a1 & MR blockmild sedative, anti-emetic
H1R antagonist; 5HT, a1 & MR blockStrong sedative, strong anticholinergic, anti-emetic
H1R antagonist; 5HT, a1 & MR blockallergies and hypersensitivities, mild anti-cholinergic, mild sedative in OTC prep
H1R antagonist; 5HT, a1 & MR blockallergies and hypersensitivities, mild anti-cholinergic, mild sedative in OTC prep
H1R antagonist; 5HT, a1 & MR blockStrong Sedation, strong antichilinergic, ant-emetic

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Created Sep 1, 2011ReportFavoriteNominate
Tags:class, drug, generic

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