Miscellaneous Quiz / urinary tract pathogens

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Can you name the urinary tract pathogens?

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HintAnswer
Cx: Alpha or no hemolysis on blood agar, resistant to 40% bile salts, 6.5% to NaCl, bacitracin, and optochin
VF: capsule, peptidase, and hydrolytic enzymes
Tx of acute uncomplicated cystitis
Other gram (-) rods
Condition with common antimicrobial resistant organisms
Pili, capsule, endotoxin
Class of pathogens: Serologic classification O (always present), H (flagellar), and K (capsular)
Bladder or kidney infection in pt with underlying structural or functional abnormalities of the GU tract
Bladder or kidney infection associated with a condition that increases the risk of failing tx (MDR pathogen)
Pathogen(s): Non-motile, lactose (+), urease (-)
Gram (+) cocci in clusters, catalase (+), coagulase (-)
Bacteria in urine without s/s attributable to UTI
Normal flora of the intestinal and upper respiratory tract that cause endogenous + nosocomial infections
Tx of acute uncomplicated pyelonephritis and complicated UTI
ADHERENCE: P-pilus (pyelonephritis associated pilus); other adhesins (FimH). DAMAGE: hemolysin (pore forming LPS)
Pathogen(s): Motile, lactose (+), urease (-)
Gram(-) rods, motile, oxidase (+), adaptability to minimal nutritional requirements
Class of pathogens: Gram (-) rods, facultative anaerobes, ferment glucose, NITRATES (+), catalase (+), OXIDASE (-)
Uncommon, can occur with severe pyelonephritis or following bacteremia from of site of infection
Blue-green colonies, grows at 42C, fruity aroma, mucoid, fluorescent under UV light
Causes UTI in pregnant women and is the main cause of meningitis in neonates
Pathogens in complicated or nosocomial infections
Gram (+) cocci
Environment colonizes skin and vaginal tract --> endogenous transmission
HintAnswer
Ubiquitous in the environment and transient flora --> a variety of opportunistic infections
Normal intestinal flora and found in the environment --> endogenous and nosocomial infections
Cx: McConkey agar: lactose (-) white, swarming motility
10-20% of UTIs in sexually active young women (cystitis)
Gram (+) cocci in chains, catalase (-), lancefield's group B (GBS)
Bladder or kidney infection in healthy, young, nonpregnant women
Pathogen(s): Lactose (+) slowly, red pigments
Cx: McConkey agar: lactose (+) pink, mucoid colonies
Normal intestinal flora --> endogenous ascending infections
Class of pathogens: LPS (lipopolysaccharide aka endotoxin), O antigen, Core polysaccharides (aka enterobacterial common antigen), lipid A (toxic part)
Cx: Red pigment, distinctive brick-red colonies
Cx: beta-hemolysis on blood agar, bile resistant
Upper respiratory and genitourinary tract flora --> endogenous infection
Pathogens in uncomplicated infections
Found in the intestinal tract --> endogenous from medical procedure, nosocomial
Cx: No hemolysis on blood agar, novobiocin resistant
Gram (+) diplococci or short chains, catalase (-), lancefield's group D
Cx: McConkey agar. Lactose (+) pink
Pathogen(s): Swarming motility, lactose (-) urease (+)
Pili; capsule, endotoxin, extracellular enzymes and toxins, pigments (pyocyanin & pyoverdin or fluorescin)
VF: adhesin, toxins, and enzymes. All strains carry some drug resistance, some are vancomycin
Adhesins, capsule, endotoxin
ADHESINS: urease (higher pH, urinary stones --> chronic infections); endotoxin

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