Miscellaneous Quiz / urinary tract pathogens

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Can you name the urinary tract pathogens?

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HintAnswer
Tx of acute uncomplicated cystitis
Condition with common antimicrobial resistant organisms
Cx: Alpha or no hemolysis on blood agar, resistant to 40% bile salts, 6.5% to NaCl, bacitracin, and optochin
10-20% of UTIs in sexually active young women (cystitis)
Class of pathogens: LPS (lipopolysaccharide aka endotoxin), O antigen, Core polysaccharides (aka enterobacterial common antigen), lipid A (toxic part)
Cx: McConkey agar: lactose (+) pink, mucoid colonies
Pathogens in complicated or nosocomial infections
Cx: Red pigment, distinctive brick-red colonies
Class of pathogens: Serologic classification O (always present), H (flagellar), and K (capsular)
Ubiquitous in the environment and transient flora --> a variety of opportunistic infections
Cx: McConkey agar. Lactose (+) pink
Pathogen(s): Lactose (+) slowly, red pigments
Pathogens in uncomplicated infections
Gram (+) cocci in chains, catalase (-), lancefield's group B (GBS)
Causes UTI in pregnant women and is the main cause of meningitis in neonates
Adhesins, capsule, endotoxin
Normal flora of the intestinal and upper respiratory tract that cause endogenous + nosocomial infections
Tx of acute uncomplicated pyelonephritis and complicated UTI
Other gram (-) rods
Cx: McConkey agar: lactose (-) white, swarming motility
Cx: No hemolysis on blood agar, novobiocin resistant
Uncommon, can occur with severe pyelonephritis or following bacteremia from of site of infection
VF: adhesin, toxins, and enzymes. All strains carry some drug resistance, some are vancomycin
Pathogen(s): Motile, lactose (+), urease (-)
HintAnswer
Upper respiratory and genitourinary tract flora --> endogenous infection
Bladder or kidney infection in pt with underlying structural or functional abnormalities of the GU tract
Gram (+) diplococci or short chains, catalase (-), lancefield's group D
Pathogen(s): Swarming motility, lactose (-) urease (+)
Environment colonizes skin and vaginal tract --> endogenous transmission
ADHERENCE: P-pilus (pyelonephritis associated pilus); other adhesins (FimH). DAMAGE: hemolysin (pore forming LPS)
Blue-green colonies, grows at 42C, fruity aroma, mucoid, fluorescent under UV light
Pili; capsule, endotoxin, extracellular enzymes and toxins, pigments (pyocyanin & pyoverdin or fluorescin)
Bladder or kidney infection in healthy, young, nonpregnant women
Normal intestinal flora and found in the environment --> endogenous and nosocomial infections
Pathogen(s): Non-motile, lactose (+), urease (-)
Bladder or kidney infection associated with a condition that increases the risk of failing tx (MDR pathogen)
Cx: beta-hemolysis on blood agar, bile resistant
ADHESINS: urease (higher pH, urinary stones --> chronic infections); endotoxin
Gram(-) rods, motile, oxidase (+), adaptability to minimal nutritional requirements
Found in the intestinal tract --> endogenous from medical procedure, nosocomial
Gram (+) cocci in clusters, catalase (+), coagulase (-)
VF: capsule, peptidase, and hydrolytic enzymes
Normal intestinal flora --> endogenous ascending infections
Bacteria in urine without s/s attributable to UTI
Class of pathogens: Gram (-) rods, facultative anaerobes, ferment glucose, NITRATES (+), catalase (+), OXIDASE (-)
Pili, capsule, endotoxin
Gram (+) cocci

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