Miscellaneous Quiz / urinary tract pathogens

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Can you name the urinary tract pathogens?

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HintAnswer
Normal flora of the intestinal and upper respiratory tract that cause endogenous + nosocomial infections
Pili; capsule, endotoxin, extracellular enzymes and toxins, pigments (pyocyanin & pyoverdin or fluorescin)
Cx: No hemolysis on blood agar, novobiocin resistant
Ubiquitous in the environment and transient flora --> a variety of opportunistic infections
Other gram (-) rods
Class of pathogens: Gram (-) rods, facultative anaerobes, ferment glucose, NITRATES (+), catalase (+), OXIDASE (-)
Pathogens in complicated or nosocomial infections
Cx: McConkey agar: lactose (+) pink, mucoid colonies
Pathogens in uncomplicated infections
Cx: McConkey agar: lactose (-) white, swarming motility
Gram (+) diplococci or short chains, catalase (-), lancefield's group D
Gram (+) cocci in chains, catalase (-), lancefield's group B (GBS)
Cx: beta-hemolysis on blood agar, bile resistant
Gram(-) rods, motile, oxidase (+), adaptability to minimal nutritional requirements
Bacteria in urine without s/s attributable to UTI
Class of pathogens: LPS (lipopolysaccharide aka endotoxin), O antigen, Core polysaccharides (aka enterobacterial common antigen), lipid A (toxic part)
Tx of acute uncomplicated pyelonephritis and complicated UTI
Condition with common antimicrobial resistant organisms
Uncommon, can occur with severe pyelonephritis or following bacteremia from of site of infection
VF: adhesin, toxins, and enzymes. All strains carry some drug resistance, some are vancomycin
Bladder or kidney infection in healthy, young, nonpregnant women
Cx: Red pigment, distinctive brick-red colonies
Cx: Alpha or no hemolysis on blood agar, resistant to 40% bile salts, 6.5% to NaCl, bacitracin, and optochin
Pathogen(s): Non-motile, lactose (+), urease (-)
HintAnswer
Normal intestinal flora --> endogenous ascending infections
Adhesins, capsule, endotoxin
Causes UTI in pregnant women and is the main cause of meningitis in neonates
Bladder or kidney infection associated with a condition that increases the risk of failing tx (MDR pathogen)
Pathogen(s): Lactose (+) slowly, red pigments
Gram (+) cocci
Tx of acute uncomplicated cystitis
Pili, capsule, endotoxin
Class of pathogens: Serologic classification O (always present), H (flagellar), and K (capsular)
VF: capsule, peptidase, and hydrolytic enzymes
Normal intestinal flora and found in the environment --> endogenous and nosocomial infections
10-20% of UTIs in sexually active young women (cystitis)
Bladder or kidney infection in pt with underlying structural or functional abnormalities of the GU tract
Pathogen(s): Motile, lactose (+), urease (-)
Upper respiratory and genitourinary tract flora --> endogenous infection
Cx: McConkey agar. Lactose (+) pink
Found in the intestinal tract --> endogenous from medical procedure, nosocomial
ADHERENCE: P-pilus (pyelonephritis associated pilus); other adhesins (FimH). DAMAGE: hemolysin (pore forming LPS)
Pathogen(s): Swarming motility, lactose (-) urease (+)
Blue-green colonies, grows at 42C, fruity aroma, mucoid, fluorescent under UV light
Gram (+) cocci in clusters, catalase (+), coagulase (-)
ADHESINS: urease (higher pH, urinary stones --> chronic infections); endotoxin
Environment colonizes skin and vaginal tract --> endogenous transmission

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