Miscellaneous Quiz / Opioids

Random Miscellaneous Quiz

Can you name the Opioids?

Quiz not verified by Sporcle

Forced Order
Also try: Died Before 30
Challenge
Share
Tweet
Embed
Score 0/81 Timer 20:00
HintAnswer
Oxycodone class
SE: Itching (via histamine release), immune modulation
Naltrexone class
Receptor subtype: Mu (+++) and Kappa (+)
Transdermal, low oral bioavailability. DOA: >1.5 hours
Parenteral only. DOA: 4-8 hours
Receptor subtype: Mu (P) and Kappa (--)
Medium oral bioavailability. DOA: 2-4 hours
SE: Resp depression (increased PaCO2 & depressed response to CO2 challenge), cough suppression, miosis, truncal rigidity, n/v, little effect on BP or HR (some exceptions)
Receptor subtype: Mu (+++)
Drug use: Analgesia (especially severe acute pain)
Drug use: Analgesia (severe acute pain), pre-sx anxiolytic, epidural & spinal analgesia, balanced anesthesia, chronic pain (patches, lollipops)
Drug use: acute opioid OD
Drug: Poor oral efficacy. Glucoronidation. DOA: 1-2 hours (IV). Repeated injected may be needed
SE: Constriction of Oddi sphincter (--> reflex of bile and pancreatic juice --> elevated plasma amylase, lipase), depressed renal function.
Hydrocodone w/ acetaminophen
Receptor subtype: Mu (--) and Kappa (++)
Drug MOA: Weak mu-receptor agonist. Serotonin and NE transporter inhibition
Naloxone class
Efficacy: high; abuse potential: low
Meperidine class
Dezocine class
Parenteral or SL only. DOA: > 8 hours. Long half life (20-70 hours)
Drug use: mild to moderate analgesia, anti-tussives
Efficacy: moderate; abuse potential: medium
Non-opioid effects: MAO inhibition, blocks NMDA (neuropathic pain)
IV only with DOA longer than naloxone
HintAnswer
Receptor subtype: Mu (P) and Kappa (++)
High oral potency. DOA 3-4 hours
Codeine w/acetaminophen
Oral only. DOA 4-5 hours
Pentazocine class
Drug use: detox tx for heroine addicts, tolerance develops slower -- analgesic rotation. Withdrawal milder; maintenance tx for heroin addicts
Low oral bioavailability. DOA: 3-4 hours
Nalmefene class
Efficacy: low; abuse potential: medium
Dihydrocodone class
Drug use: Mild analgesia, 1/2 as potent as codeine
Drug use: acute opioid OD, possible use in decreasing ETOH cravings in addicts
Drug use: Analgesia, pre-sx anxiolytic, epidural & spinal analgesia, balanced anesthesia (buprenorphine may be > effective than methadone in detox & maintenance tx in heroin users
Receptor subtype: Mu (P) and Kappa (+++)
Methadone class
Parenteral. DOA: > 0.75 hours
SE: Increased tone of the ureter, bladder, and sphincter (--> urinary retention), decreased uterine tone (may prolong labor).
Parenteral only. DOA: 3-4 hours
SE: in dependent pts --> instant abstinence (withdrawal syndrome)
SE: seizures, neuropathic pain. Little respiratory effects
Receptor subtype: Mu (+)
Analgesia (severe acute pain), pre-sx anxiolytic, epidural & spinal regional analgesia, balanced anesthesia, dyspnea.
Drug use: Mild to moderate analgesia
Buprenorphine class
Well absorbed orally. Strong first pass effect. DOA: up to 48 hours
SE: Analgesia, euphoria (floating sensation, no anxiety or distress), rarely dysphoria (restlessness, malaise), sedation, drowsiness.
Codeine w/ aspirin
HintAnswer
Butorphanol class
Parenteral. DOA: > 1.5 hours
Codeine class
Hydrocodone w/ ibuprofen
SE: Peripheral arterial & venous dilation, may increase ICP when pCO2 rises, constipation, decreased motility, increase in GI tone & spasms, biliary colic
Receptor subtype: Mu (+++), Delta (+), and Kappa (+)
Efficacy: moderate. Abuse Potential: low
Medium oral potency. DOA 3-4 hours
Oxycodone w/ acetaminophen
Low oral bioavailability. DOA: 4-5 hours
Nalbuphine class
Efficacy: very low; abuse potential: low
Receptor subtype: Mu (P) and Delta (++)
Non-opioid effects: Antimuscarinic, (tachycardia), blocks serotonin reuptake (contraindicated w/ MAOIs), active metabolite can produce seizure in pts w/ renal failure
Tramadol class
Oxycodone w/ aspirin
SE: Neuroendocrine effects (stimulate the release of ADH, prolactin, somatotropin, inhibit the release of LH), pruritis, flushing, warm skin, sweating.
Hydrocodone class
Levorphanol class
High oral bioavailability.DOA: 4-6 hours
Parenteral. DOA: > 0.05 hours
Medium oral bioavailability, not SC (irritant). DOA: 3-4 hours
Efficacy: high; abuse potential: high
Drug Effects: Almost inert in the absence of an agonist. Reverses opioid effect completely in 1 - 3 minutes. Normalizes resp, consciousness, pupil size, & bowel activity.
Receptor subtype: Mu (++) [10% to morphine] and Delta (+)
Addiction/Withdrawal: No tolerance develops, no abstinence symptoms after withdrawal of antagonists after chronic administration
Fentanyl class

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.