Miscellaneous Quiz / Lipid Lowering Agents

Random Miscellaneous Quiz

Can you name the Lipid Lowering Agents?

 Plays Quiz not verified by Sporcle

Forced Order
Challenge
Share
Tweet
Embed
Score 0/38 Timer 15:00
QuestionAnswer
Synergistic with statins
Decreases VLDL and TG, increases LPL activity
Upregulates LPL, apo AI, AII
Atorvastatin
SE: flushing, itching, GI upset, hepatic dysfunction, hyperuricemia, tachyarrhythmias
Fluvastatin
Decreases VLDL, LDL, Lp(a) and increases HDL
Lovastatin
Use 2-3 of these agents to treat defective apo-B or familial hypercholesterolemia (Type IIa)
Colestipol
Cholestyramine
Downregulates apo CIII
Single agent to treat familial dysbetalipidemia
Contraindicated in DM, peptic ulcers, chronic liver dz, gout
Anion exchange resin prevents bile acid binding
Decreases CRP
Use 2 - 3 of these agents to treat familial combined hyperlipoproteinemia
Colesevelam
Single agent to treat hyperlipoproteinemia (type I) or familial hypertriglyceridemia (type IV)
QuestionAnswer
Pravastatin
Contraindicated in dysbetalipoproteinemia (TG>400) and relatively contraindicated in TG >200
SE: Gallstones, elev liver enzymes, increased action of oral anticoagulants
Decreases LDL
Take this drug to decrease flushing with Niacin
Drug interaction with digitalis, warfarin, statins, aspirin, ascorbic acis, iron AND a decrease in fat soluble vitamins
Fenofibrate
Gemfibrozil
Decreases LDL and TG
Rosuvastatin
Decreases FFA to liver
Niacin/Nicotinic acid/Vit B3
Ezetimibe
Contraindicated in pregnancy and liver dz
Simvastatin
Competitively inhibits HMG-CoA reductase
Contraindicated in kidney, liver, and biliary dz
Inhibits NPC1L1 transport in the gut
Must monitor creatine kinase

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
OR
Log In

You Might Also Like...

Show Comments

Extras

Created Mar 14, 2011ReportNominate
Tags:agent

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.

Report this User

Report this user for behavior that violates our Community Guidelines.

Details: