Miscellaneous Quiz / fungal pathogens

Random Miscellaneous Quiz

Can you name the fungal pathogens?

Quiz not verified by Sporcle

Forced Order
Score 0/53 Timer 15:00
Patho: inhalation (infective form unclear) -> proliferation in alveoli -> foamy alveolar infiltrate -> dissemination
Reservoir: Soil - South America
Tx of pneumocystosis
Reservoir: Desert sand - southwestern US
Clinical presentation: inhalation of sporangiospores -> hyphae formation -> angioinvasive fungi
Reservoir: Soil with decaying organic material - Eastern US
True pathogens definition
Disease caused by Histoplasma capsulatum
Pathogenesis: granulomatous inflammatory reaction/possible dissemination
Dx: Microscopy, culture on sabouraud agar (25C vs. 37C), serologic tests (Ab detection tests), X-ray
Opportunistic, monomorphic pathogens
Tx of cryptococcosis
Reservoir: Ubiquitous in soil
Tx of aspergillosis, zygomycosis, and mucormycosis
Environment & cx at 25C: Mold: hyphae + nondescript conidia
Key characteristics: Single-celled eukaryotic microorganism. LIFE CYCLE = tropozoites, precyst, cyst. NO ERGOSTEROL IN THE CELL MEMBRANE
Transmission: inhalation from environment. No human-to-human transmission
Key characteristics: Filamentous fungus (mold)
Dx: Microscopy, cx on sabouraud agar, serologic tests, X-ray
Bind to host cells -> turn into yeast cells (extracellular); dissemination: multiple organs, skin (cutaneous form)
Patho: inhalation of conidia -> germination into hyphae -> tissue invasion; angioinvasive fungi
Clinical presentation from self-limiting flu-like illness to severe pulmonary infection (similar to TB) and disseminated conditions
Tissue & cx at 37C: INTRACELLULAR BUDDING YEASTS in reticuloendothelial cells
Environment & cx at 25C: Mold: hyphae + barrel-shaped arthroconidia
Disease caused by Crytococcus neoformans
Tx of mild to moderate dz from true pathogens
Predisposing conditions: AIDS pts, immunocompromised, or metabolic disorders (DM)
Transmitted from inhalation of dust containing conidia. No human-human transmission
Key characteristics: ENCAPSULATED YEAST
Patho: inhalation of sporangiospores -> hypae formation ->angioinvasive fungi
Clinical presentation: pulmonary infections, dissemination (meningitis in AIDS pts)
Tissue & cx at 37C: budding yeasts with 'PILOT WHEEL' MORPHOLOGY
Environment & cx at 25C: Mold: septae hyphae + nondescript conidia
Reservoir: Soil enriched with pigeon droppings
Disease caused by Coccidioides immitis
Cx at 37C: mold (no thermal dimorphism). Tissue at 37C: SPHERULES filled with endospores
Patho: inhalation of aerosolized yeast -> production of capsule in alveoli, multiplication -> granulomatous lesions -> dissemination (CNS)
Life cycle of alternating spherules and progeny endospores; dissemination via endospore propagation (skin, CNS, bone...)
Disease caused by Aspergillus, fumigatus, and flavus
Conidia turn into yeast cells -> multiplication inside macrophages; dissemination via macrophages -> skin, reticuloendothelial system
Disease caused by Blastomyces dermatitidis
Reservoir: Soil contaminated by bird or bat feces - Eastern US
Clinical presentation: allergic bronchopulmonary aspergillosis; fungal ball (aspergilloma); invasive pulmonary aspergillosis
Clinical presentation: inhalation (infective form unclear) -> proliferation in alveoli -> foamy alveolar infiltrate -> dissemination
Disease caused by Pneumocystis jiroveci
Tx of severe or disseminated dz from true pathogens
True pathogens
Bind to host cells -> turn into yeast cells; dissemination: skin, mucosa, lymphoid organs....
Disease caused by Paracoccidioides brasiliensis
Environment & cx at 25C: Mold: hyphae + micro & macroconidia
Disease caused by Rhizopus and Mucor

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
Log In

You Might Also Like...

Show Comments


Top Quizzes Today

Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.