Miscellaneous Quiz / Anti-glycemic Agents

Random Miscellaneous Quiz

Can you name the Anti-glycemic Agents?

Quiz not verified by Sporcle

Forced Order
Challenge
Share
Tweet
Embed
Score 0/99 Timer 20:00
HintAnswer
Humalog 50/50 class
Peak 2 - 5 hours
Duration 18-24 hours (12-16 hours)
Humulin 70/30
Metformin class
NPH Iletin III (Lilly) class
Use: Onset and duration are rough within the range listed from person to person
MOA: GLP-1 agonist. Has all the properties of human GLP-1. 10 lb or greater wt loss in 1 yr
Novolog Mix 70/30 class
Humulin Ultralente class
MOA: Increases hepatic insulin sensitivity. Works through AMP dependent kinase, a mastor allosteric regulator of metabolism, that senses lack of energy substrates in cells.
Humalog Mix 50/50 class
Novolog Mix 70/30 PenFill class
Nololin 70/30
Novolin N class
Duration 5-7 hours (6 - 8 hours)
Miglitol class
Rosiglitazone and metformin combo
SE: Nausea, other GI effects, rare reports of pancreatitis
Exenatide class
Peak 6-8 hours
SE: Similar to sulfonureas but with less risk of prolonged hypoglycemia.
Contraindications: Renal dz, liver dz, CHF, dehydration, shock, acidosis, alcoholism
Metformin and glipizide combo
Acarbose class
P-kinetics: 100 mg once daily
Metformin and pioglitazone combo
Onset 15-30 minutes
Humulin L (Lente) (Lilly) class
Avapro - Novalog (Novo Nordisk) class
Humalog 75/25 Mix class
Sitagliptin (Januvia) class
Pioglitazone (Actos) class
HintAnswer
Humulin N (NPH) (Lilly) class
Lispro - Humalog (Lilly) class
MOA: Decreases hepatic glucose production, decreases peripheral insulin resistance, increases glucose uptake, decrease gluconeogenesis, decreases fatty liver,
Detemir - Levemir class
MOA: Similar to sulfonureas.
Glargine - Lantus class
P-kinetics: Eliminated by renal filtration
Glusine - Apidra (Avemtis) class
SE: No hypoglycemia
SE: Increased plasma volume, edema, CHF, ovulation in PCO, mild anemia, rare liver toxicity, risk of fx in women. No hypoglycemia
Rosiglitazone and glimepiride combo
MOA: Decreases insulin resistance, increase muscle and adipose tissue glucose uptake, decreased hepatic glucose output.
Peak: None
MOA: Bind to SU receptor on surface of beta cells, closing K+ATP channels -> to depolarization of cell membrane, allowing Ca++ to enter cell -> in insulin secretion.
Onset 1-4 hours
Humalog Mix 75/25 class
Sitagliptin and metformin combo
Humulin 50/50
Humalog class
Glipizide (Glucotrol; Glucotrol XL) class
MOA: Lowers threshold for insulin release. Effective early; secondary failure common.
MOA: Binds to PPAR-gamma, a nuclear receptor regulating differentiation of cells (adipocytes, vascular tissue). Decreased plasma fatty acid levels, decreased central adiposity, res
Use: Controls blood sugar between meals and during sleep
Duration ~14 hours
Humulin Br class
Duration: 20-24 hours
Use: Human insulin is made by recombinant technology
P-kinetics: Injected SQ BID
Nolvin N PenFill
Apidra class
Nolovin R PenFill
Duration: 18-20 hours
Repalinide class
HintAnswer
Humulin R (Lilly) class
Novolin R class
SE: GI effects, occasional low B12, rare lactic acidosis, ovulation in PCO
Use: Combines rapid-acting and intermediate-acting insulin. Controls blood sugar at mealtime and all day and night
Novolog Mix 70/30 class
SE: Hypoglycemia, weight gain, GI effects.
MOA: Effective in long-duration DM, weight loss, no hypoglycemia, lowers insuling, TG, LDL
P-kinetics: Rapid absorption, short duration.
Novolin 70/30 class
Novolin 70/30 PenFill
Contraindications: Intestinal dz, cirrhosis, renal dz (creatinine > 2)
Duration 3 - 4 hours (4-5 hours)
Use: First-line for most DM II, esp. obese.
Glimepiride (Amaryl) class
Humulin N class
SE: GI effects, increased transaminases (monitor). No hypoglycemia
MOA: Lowers postprandial glucose rise by delaying CHO absorption. Decreases glucose absorption secondary to decreased digestion of carbohydrates.
Contraindications: Class III/IV CHF
Onset 30 minutes - 1 hour
Novolog class
Regular Ileting II (Lilly) class
Use: Controls blood sugar surges at mealtime
MOA: Inhibit enzymatic degradation of incretin hormones. Unlike most PO meds for DM, does not promote wt gain, there may even be slight wt loss.
Nololin N (NPH) (Lilly) class
Glyburide (Micronase, Diabeta) class
Peak: 1 hour
Pioglitazone and glimepiride combo
Novolin R PenFill
Use: DM II. Most effective in lean patients.
Rosiglitazone (Avandia) class
Novolin R (Novo Nordisk) class
Onset: 1-2 hours
Metformin and glyburide combo

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras


Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.