Anti-arrhythmia drugs Quiz Stats

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Hint Answer % Correct
Caution in CHF, asthmas, COPD, MAOI, eldery, depressed, PVDClass II
69.2%
Class IB drugsLidocaine, Mexiletine, Tocainide
65.4%
Class IA DrugsQuidine, Procainamide, Disopyramide
61.5%
Class IA drug that also blocks alpha-RQuinidine
61.5%
IV only class 1B drug with a wide therapeutic windowLidocaine
61.5%
AmiodaroneClass III
61.5%
Blocks K channelsClass III
61.5%
SE pulmonary fibrosis, liver tox, hypothyroid, photosensitivty, corneal discoloration, blue skinAmiodarone
61.5%
Quidine is metabolized by the .....Liver
57.7%
IbutilideClass III
57.7%
DofetilideClass III
57.7%
Na channel blockerClass I
57.7%
Need to monitor PFTs, LFTs, and TFTsAmiodarone
57.7%
MOA: decrease phase 4 spontaneous depolarization, slows conduction in cells dependent on Ca current. Also vasodilatesClass IV: Diltiazem, Verapamil, Bepridil
57.7%
Class IA drug that also blocks N-RProcainamide
53.8%
MOA: blockade of open and inactivated sodium channels -> shortened AP, decreased slope of repolarization, and shortened phase 3 repolarizationClass IB
53.8%
Class IC drugsFlecainide, Propafenone
53.8%
Class IC drug with weak beta blocking activityPropafenone
53.8%
Class II drug used in surgery and acute arrhythmiasEsmolol
53.8%
Class IV drugsDiltiazem, Verapamil, Bepridil
53.8%
SE: safe, flushing, SOB, hypotension, transient asystoleAdenosine
53.8%
Disopyramide is excreted by the....Kidneys
50%
SE: more pronounced SA and AV block, lupus erythmatosus like syndrome, ganglion blockadeProcainamide
50%
DOC for ventricular arrhythmias, esp. post-MI and cardioversionLidocaine
50%
Used in rate control for supraventricular arrythmias including A fib, A flutterClass II
50%
BretyliumClass III
50%
Class III drugs with high affinity for inactive channelsAmiodarone
50%
Hint Answer % Correct
Used in supraventricular and ventricular tachy-arrhythmias, paroxsymal A fibAmiodarone
50%
Procainamide is excrexted by the....Kidneys
46.2%
SE: arrythmias, N/V, diarrhea, cinchonism, displaces digoxin from tissue binding site, thrombocytopenia, hepatitis, angioneurotic edemaQuinidine
46.2%
SE: least toxic for cardiac arrhythmias, CNS, drowsiness, slurred speech, paresthesia, agitation, convulsionsClass IB
46.2%
MOA: blockade of open and inactivated sodium channels -> no effect on AP duration, slows phase 0 depolarization, decreases conduction velocityClass IC: Flecainide, Propafenone
46.2%
Class II DrugsEsmolol, Metoprolol, Pindolol, Propanolol
46.2%
MOA: beta-1 selective beta blockadeEsmolol, Metoprolol
46.2%
Other: Used in digitalis associated arrhythmias, torsades de pointes, and acute MIMgCl
46.2%
DOC for paroxsymal supraventricular tachycardia and V tachAdenosine
46.2%
MOA: high affinity for blockade of open Na channels and also K channels -->decrease phase 0 depolarizing slope, prolong AP, decrease phase 4 spontaneous depolarizationClass IA
42.3%
Class IB drug with pulmonary fibrosis as a side effectTocainide
42.3%
MOA: partial beta agonistPindolol
42.3%
Contraindicated in WPWBeta blockers and Verapamil
42.3%
SotololClass III
42.3%
Other antiarrhythmiasAdenosine, Digoxin, MgCl
42.3%
MOA: non-selective beta blockadePropanolol
38.5%
Decreases sudden death MI for sustained ventricular tachycardiaSotolol
38.5%
SE: profound anti-muscarinic effects, dry mouth, urinary retention, blurred vision, constipation, confusion, convulsions, etc.Disopyramide
34.6%
Other: Used in SV arrhythmias, Afib, Aflutter, controls ventricular response rateDigoxin
34.6%
Used in conversion in a fib and a flutterIbutilide
34.6%
Used to maintain SR after cardioversion of A fib and A flutterDofetilide
34.6%
SE: torsades de pointesSotolol, Ibutilide, Dofetilide, Bretylium
30.8%
Preferential for ectopic arryhythmias and ventricular arrhythmias d/t increased automaticity and reentryClass IA
26.9%
Used in life threatening ventricular arrhythmias when lidocaine and cardioconversion have failedBretylium
26.9%
Used in refractory ventricular arrythmias and some SVT -- oral with long half lifeClass IC: Flecainide, Propafenone
23.1%
Class III IV onlyBretylium
23.1%

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Created Mar 15, 2011ReportNominate
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