Angina Drugs

Can you name the Angina Drugs?

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HintAnswer
Dihydropiridine used in HTN, stable and vasospastic angina
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine
Subclass of Ca channel blocker with more cardiac effects
Immediate relief drug from stable angina
SE: fatigue, impotence, ED, inability to exercise
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption
Slow onset Ca channel blocker
Gas, inhaled nitrate/nitrite
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's
Very long half life Ca channel blocker
Dihydropiridine used in stable and vasospastic angina, HTN, CHF
Isosorbide dinitrate
Nitroglycerin
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's
Dihydropiridine used in HTN
HintAnswer
CCB contraindications
Medium onset Ca channel blocker
Slowest onset Ca channel blocker
Can be given sublingual, transdermal, IV
Dihydropiridine used in HTN, Raynaud's, CHF
Fast onset Ca channel blocker
Classes of drugs used in vasospastic angina
BB contraindications
Dihydropiridine used in SAH, migrainge prophylaxis
Fast medium onset Ca channel blocker
BB used in stable and unstable angina BUT not vasospastic angina
Amyl Nitrate
Class contraindicated in increased ICP
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia
Also called Prinzmetal's angina
CCB: compelling indication
Subclass of Ca channel blocker with more vascular effects
Isosorbide mononitrate

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