Miscellaneous Quiz / Angina Drugs

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Can you name the Angina Drugs?

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Slow onset Ca channel blocker
Classes of drugs used in vasospastic angina
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption
Amyl Nitrate
Fast onset Ca channel blocker
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia
Medium onset Ca channel blocker
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil
Isosorbide mononitrate
SE: fatigue, impotence, ED, inability to exercise
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions
Dihydropiridine used in HTN, Raynaud's, CHF
CCB contraindications
Subclass of Ca channel blocker with more cardiac effects
Fast medium onset Ca channel blocker
Dihydropiridine used in SAH, migrainge prophylaxis
Dihydropiridine used in HTN, stable and vasospastic angina
Dihydropiridine used in HTN
Immediate relief drug from stable angina
Also called Prinzmetal's angina
Can be given sublingual, transdermal, IV
Very long half life Ca channel blocker
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP
CCB: compelling indication
Isosorbide dinitrate
BB used in stable and unstable angina BUT not vasospastic angina
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine
Subclass of Ca channel blocker with more vascular effects
Gas, inhaled nitrate/nitrite
Dihydropiridine used in stable and vasospastic angina, HTN, CHF
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's
Class contraindicated in increased ICP
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's
Slowest onset Ca channel blocker
BB contraindications

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Created Mar 15, 2011ReportNominate

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