Miscellaneous Quiz / Angina Drugs

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Can you name the Angina Drugs?

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HintAnswer
Medium onset Ca channel blocker
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia
Isosorbide mononitrate
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's
BB contraindications
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's
Dihydropiridine used in HTN
Fast medium onset Ca channel blocker
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions
Very long half life Ca channel blocker
Slowest onset Ca channel blocker
Nitroglycerin
CCB: compelling indication
Isosorbide dinitrate
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil
Fast onset Ca channel blocker
Class contraindicated in increased ICP
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP
HintAnswer
Can be given sublingual, transdermal, IV
Dihydropiridine used in stable and vasospastic angina, HTN, CHF
BB used in stable and unstable angina BUT not vasospastic angina
Slow onset Ca channel blocker
Dihydropiridine used in SAH, migrainge prophylaxis
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption
Dihydropiridine used in HTN, stable and vasospastic angina
CCB contraindications
Amyl Nitrate
Gas, inhaled nitrate/nitrite
Dihydropiridine used in HTN, Raynaud's, CHF
Also called Prinzmetal's angina
Subclass of Ca channel blocker with more vascular effects
Subclass of Ca channel blocker with more cardiac effects
Immediate relief drug from stable angina
SE: fatigue, impotence, ED, inability to exercise
Classes of drugs used in vasospastic angina
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine

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