Miscellaneous Quiz / Angina Drugs

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Can you name the Angina Drugs?

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CCB: compelling indication
Dihydropiridine used in HTN, Raynaud's, CHF
Immediate relief drug from stable angina
Amyl Nitrate
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's
Isosorbide mononitrate
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia
Classes of drugs used in vasospastic angina
Fast medium onset Ca channel blocker
Slowest onset Ca channel blocker
Slow onset Ca channel blocker
Gas, inhaled nitrate/nitrite
Subclass of Ca channel blocker with more vascular effects
Also called Prinzmetal's angina
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP
Medium onset Ca channel blocker
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's
Isosorbide dinitrate
Class contraindicated in increased ICP
Can be given sublingual, transdermal, IV
Fast onset Ca channel blocker
BB contraindications
Dihydropiridine used in HTN, stable and vasospastic angina
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine
Dihydropiridine used in stable and vasospastic angina, HTN, CHF
BB used in stable and unstable angina BUT not vasospastic angina
Dihydropiridine used in SAH, migrainge prophylaxis
SE: fatigue, impotence, ED, inability to exercise
Dihydropiridine used in HTN
Very long half life Ca channel blocker
CCB contraindications
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil
Subclass of Ca channel blocker with more cardiac effects
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions

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Created Mar 15, 2011ReportNominate

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