Miscellaneous Quiz / Angina Drugs

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Can you name the Angina Drugs?

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Gas, inhaled nitrate/nitrite
Slow onset Ca channel blocker
SE: fatigue, impotence, ED, inability to exercise
Can be given sublingual, transdermal, IV
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption
Isosorbide dinitrate
Classes of drugs used in vasospastic angina
BB used in stable and unstable angina BUT not vasospastic angina
Amyl Nitrate
Subclass of Ca channel blocker with more vascular effects
Also called Prinzmetal's angina
Isosorbide mononitrate
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia
Dihydropiridine used in HTN
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine
BB contraindications
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil
Fast medium onset Ca channel blocker
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's
Immediate relief drug from stable angina
Dihydropiridine used in HTN, stable and vasospastic angina
CCB contraindications
Slowest onset Ca channel blocker
Subclass of Ca channel blocker with more cardiac effects
Medium onset Ca channel blocker
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions
Dihydropiridine used in SAH, migrainge prophylaxis
Dihydropiridine used in stable and vasospastic angina, HTN, CHF
Dihydropiridine used in HTN, Raynaud's, CHF
Very long half life Ca channel blocker
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP
CCB: compelling indication
Class contraindicated in increased ICP
Fast onset Ca channel blocker

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Created Mar 15, 2011ReportNominate

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