Hint | Answer |
Nitroglycerin | |
CCB: compelling indication | |
Dihydropiridine used in HTN, Raynaud's, CHF | |
Immediate relief drug from stable angina | |
Amyl Nitrate | |
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, and Raynaud's | |
Isosorbide mononitrate | |
MOA to block open Ca channels on smooth muscle cells -> calcium mediated excitation contraction coupling ->decreased myocardial O2 consumption | |
Non-dihydrodipine used in stable and vasopastic angina and arrhythmia | |
Classes of drugs used in vasospastic angina | |
Fast medium onset Ca channel blocker | |
Slowest onset Ca channel blocker | |
Slow onset Ca channel blocker | |
Gas, inhaled nitrate/nitrite | |
Subclass of Ca channel blocker with more vascular effects | |
Also called Prinzmetal's angina | |
SE: increased K, edema, heart block, hypotension, bradycardia, nausea, constipation, liver dysfunction, increased MI risk d/t sympathetic response to sudden drop in BP | |
Medium onset Ca channel blocker | |
| Hint | Answer |
Dihydropiridine used in stable and vasopastic angina, HTN, migraine, cardiomyopathy, Raynaud's | |
Isosorbide dinitrate | |
Class contraindicated in increased ICP | |
Can be given sublingual, transdermal, IV | |
Fast onset Ca channel blocker | |
BB contraindications | |
Dihydropiridine used in HTN, stable and vasospastic angina | |
Non-dihydrodipine used in stable and vasospastic angina, HTN, arrhythmia, migraine | |
Dihydropiridine used in stable and vasospastic angina, HTN, CHF | |
BB used in stable and unstable angina BUT not vasospastic angina | |
Dihydropiridine used in SAH, migrainge prophylaxis | |
SE: fatigue, impotence, ED, inability to exercise | |
Dihydropiridine used in HTN | |
Very long half life Ca channel blocker | |
CCB contraindications | |
Class to use with caution in conjunction with Sildenafil, tadalafil, vardenafil | |
Subclass of Ca channel blocker with more cardiac effects | |
MOA to donate NO ->cGMP -> SM relaxation via inactivation of MLCK -> Vasodilation of large veins and arteries -> decreased myocardial O2 consumptions | |
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