Miscellaneous Quiz / Alcohols

Random Miscellaneous Quiz

Can you name the Alcohols?

 Plays Quiz not verified by Sporcle

Forced Order
Also try: 'H' Blitz
Challenge
Share
Tweet
Embed
Score 0/51 Timer 20:00
HintAnswer
Drug Acute Mgmt: Prevent respiratory depression & aspiration, glucose to manage hypoglycemia & thiamine to protect against Wernicke-Korsakoff syndrome
Drug MOA: Inhibits alcohol dehydrogenase
Acamprosate class
Drug MOA and tox: metabolized by alcohol dehydrogenase to oxalic acid.
Naltrexone class
Drug P-kinetics: IV, long acting--self tapering
Drug SE: Stages - 1) Acute Stage (minutes): excitation followed by CNS depression. 2) 4-12 hrs = severe metabolic acidosis (acid metabolites accumulate), anion gap & osmolar gap ac
Drug MOA: Alters membrane-bound neuronal ion conductance & GPCR receptors: Acute decrease NMDA channel conductance & increase GABA-A Cl- channel conductance. Chronic exposure: adap
Drug P-kinetics: IV, oral short acting, no active metabolites,
Drug Use: Deterrent to relapse in individuals w/ alcoholism. After one drink acetaldehyde accumulates producing unwanted side effects of HA, flushing, n/v, & hypotension
Drug P-kinetics: Metabolized by alcohol dehydrogenase to formaldehyde. Formaldehyde is metabolized to CO2 by folate-dependent systems
Drug MOA: Increase frequency of firing of GABA-A chloride channels
Drug P-kinetics: IV until asymptomatic
Drug P-kinetics: Zero order kinetics (saturatable). Ethanol converted to acetaldehyde by alcohol dehydrogenase (NAD+ required). Acetaldehyde converted to acetate by aldehyde dehydr
Drug Use: To prevent Wernicke-Korsakoff syndrome in chronic alcoholics
Acute toxicity: dose dependent CNS depressant, CV depressant, smooth muscle relaxant.
Drug P-kinetics: IM injections (monthly) or oral (Daily)
Drug MOA: Competitive NMDA receptor antagonist?
Drug P-kinetics: Oral
Drug MOA: Required for synthesis of the coenzyme thiamine pyrophosphate
Drug P-kinetics: Oral short acting, no active metabolites,
Drug SE: Hepatotoxicity, avoid w/ disulfiram. Precipitate withdrawal in patients using heroine or other opioids.
Lorazepam class
Drug SE: Allergies, tachycardia, BP changes, flatulence, impotence, GI distress & rash
Drug Tx: Key to dx is anion gap acidosis, osmolar gap, & oxalate crystals in urine. Tx: similar to methanol poisoning. 4-methylpyrazole (an inhibitor of alchohol dehydrogenase) if
Drug P-kinetics: IV
HintAnswer
Drug to decrease chronic ethanol use
Fomepizole class
Drug MOA: Opioid receptor antagonist. Mu opioid antagonist--decreases opioid binding in reward pathways
Drug SE: none
Drug Withdrawal Mgmt: Withdrawal symptoms (motor agitation, anxiety, insomnia, seizures, visual hallucinations, delirium tremens): Mild--thiamine, restore electrolytes. Moderate to
Oxazepam class
Drug MOA: Inhibits aldehyde dehydrogenase producing accumulation of acetaldehyde after the consumption of alcohol
Drug SE: Seizures, HA, nausea, dizziness, rash, metallic taste, abnormal smell, rare allergic reactions.
Ethylene glycol class
Ethanol class
Drug P-kinetics: Alcohol dehydrogenase converts ethylene glycol into oxalic acid (renal toxic crystals)
Disulfiram class
Methanol class
Drug MOA & tox: Formaldehyde formed by conversion of methanol via alcohol dehydrogenase results in in toxicity
Clinical Use: Used for methanol, ethylene glycol poisoning. Given IV (5-10% w/ 5% dextrose in H2O) to saturate alcohol dehydrogenase
Drug Tx: Ethanol IV w/ dextrose in water or Fomepizole to inhibit conversion by alcohol dehydrogenase. Hemodialysis. Bicarbonate for acidosis. Folic acid to speed breakdown of form
Clinical Use: Reduce seizure threshold and stop seizure activity during ethanol withdrawal
Drug use: Prevent the conversion of either ethylene glycol or methanol by alcohol dehydrogenase into toxic compounds (oxalic acid or formaldehyde, respectively).
Thiamine class (B1)
Drug P-kinetics: Oral delayed release
Chronic toxicity: liver dz, CA, accidents, suicide, chronic pancreatitis, gastritis, malabsorption of vitamins. Tolerance & dependence, Neurotoxicity (Wernicke-Korsakoff syndrome),
Drugs use: Reduce cravings for alcohol & alcohol relapse (when given with counseling) in the short term. Reduces subjective 'high' assoc w/ alcohol.
Diazepam class
Drug SE: Toxicities are why it is used. Inhibits metabolism of other drugs. Hepatotoxicity
Drug SE: Visual disturbances ('snow storm'), blurred vision, retinal damage. Formaldehyde on breath or urine, bradycardia, prolonged coma, seizures, severe metabolic acidosis w/ el

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Join for Free
OR
Log In

You Might Also Like...

Show Comments

Extras

Created Aug 21, 2011ReportFavoriteNominate
Tags:alcohol

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.

Report this User

Report this user for behavior that violates our Community Guidelines.

Details: