Science Quiz / Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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InfoAnswerdetails
Familial polyposis
Gene product regulates DNA repair
Li Fraumeni
Cerebellar hemang, retinal angioma, bilat RCC and PCC
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Breast, ovary carcinomas
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
activated by p53 product to promote apoptosis
InfoAnswerdetails
Wilms' tumor
Gene product inhibits going from G1-S (not Rb or p53)
Lung colon, breast carcinomas
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Regulates nuclear transcription (not VHL)
Pancreatic and colorectal carcinomas
Regulates nuclear transcription (not WT1)
Gene product inhibits going from G1-S (not TGF beta or p53)
OSTEOSARCOMA, breast carcinoma, retinoblastoma

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Created Nov 27, 2012ReportNominate
Tags:Nintendo Quiz, detail, gene, table

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