Science Quiz / Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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Regulates nuclear transcription (not WT1)
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Gene product inhibits going from G1-S (not TGF beta or p53)
OSTEOSARCOMA, breast carcinoma, retinoblastoma
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Wilms' tumor
activated by p53 product to promote apoptosis
Gene product regulates DNA repair
Li Fraumeni
Lung colon, breast carcinomas
Breast, ovary carcinomas
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Familial polyposis
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
Cerebellar hemang, retinal angioma, bilat RCC and PCC
Regulates nuclear transcription (not VHL)
Pancreatic and colorectal carcinomas
Gene product inhibits going from G1-S (not Rb or p53)

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Created Nov 27, 2012ReportNominate
Tags:Nintendo Quiz, detail, gene, table

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