Science Quiz / Proto-oncogenes (Goljan Table 8-3)

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Can you name the Proto-oncogenes (Goljan Table 8-3)?

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InfoAnswerdetails
mutation in Neuroblastoma
Point mutation of this PO causes leukemia and carcinomas on LUNG, COLON, and PANCREAS
RAS and RET have what type of mutations
PO product fxns in GTP signal transduction
Type of mutation in HER
PO in Burkitts
type of mutation in CML
Protooncogene of CML
PO in Neuroblastoma
P.O. of aggressive breast carcinoma
InfoAnswerdetails
Mutation in SIS
PO product is a nonreceptor tyrosine kinase
8:14 translocation
Type of RAS mutations
translocation in CML
PO product fxns in nuclear transcription
9;22 translocation
Type of mutation in Burkitts
PO in MEN 2a and 2b
PO in osteosarcoma and atrocytoma

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