Science Quiz / Papulosquamous and Skin neoplasia

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Can you name the derm stuff?

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Characteristics Answerdetails
Helper cells in psoriasisvs Th2s in eczematous conditions
multiple large􏰀nevi􏰀with􏰀irregular pigmentation􏰀&􏰀irregular borders; irregularly􏰀'fried􏰁egg'􏰀looking􏰀melanocytes􏰀in􏰀the􏰀epidermal􏰁dermal􏰀j
Characteristic􏰀parakeratosis􏰀(retention􏰀of􏰀nuclei); Epidermal􏰀proliferation􏰀with􏰀acanthosis􏰀(thickening); Spongiosis􏰀(epidermal􏰀edema)􏰀with􏰀􏰀
Multiple􏰀EICs; FAP, mult soft tissue tumorsgardner's syndrome
firm,􏰀dermal nodular􏰀scars; proliferation􏰀of􏰀connective􏰀tissue􏰀(collagen)􏰀as􏰀a􏰀fibroblastic􏰀response􏰀to􏰀injury (e.g.􏰀ear􏰀piercing), Blacksif not bulging-> hypertrophic scar
Asymptomatic small􏰀flat􏰁topped􏰀papules􏰀that􏰀spread􏰀along􏰀line􏰀of􏰀Blaschko on􏰀armLS
LP occuring􏰀on􏰀lower􏰀legs,􏰀extremely􏰀extremely􏰀itchyhypertrophic lichen planus
red􏰀scaling (hyperkeratosis)􏰀papules􏰀with􏰀'sandpaper􏰀feel'􏰀surface; epidermal􏰀atypia􏰀that􏰀does􏰀NOT􏰀involve􏰀full􏰁thickness􏰀&􏰀parakeratosactinic keratosis; percursor to SCC
small􏰀red􏰀papules􏰀on􏰀skins; proliferation􏰀of􏰀dilated􏰀capillaries􏰀&􏰀venules􏰀in􏰀lobules; benignacq cherry....
brown􏰀papules􏰀(raised􏰀&􏰀pigmented);􏰀present􏰀at􏰀both at􏰀the􏰀epidermal􏰁dermal􏰀junction􏰀 &􏰀in􏰀the􏰀dermisnevus
Melanoma lacking pigmentation, spreading via nervesAmelanotic melanoma, hard to dx
benign􏰀pigmented􏰀skin􏰀neoplasm􏰀that􏰀appears􏰀'stuck􏰁on'􏰀&􏰀verrucous; acanthosis􏰀with􏰀'horn􏰀pseudocyst'seborrheic keratosis
􏰀increase􏰀of􏰀melanin􏰀pigment􏰀in􏰀basal keratinocytes,􏰀NO􏰀melanocyte􏰀hyperplasiafreckles
firm, brown􏰀nodules􏰀on􏰀legs􏰀of􏰀middle􏰁aged􏰀women with􏰀'dimple􏰀sign'􏰀on􏰀compression; proliferation􏰀of􏰀fibroblasts􏰀in􏰀dermis (does􏰀NOTbenign fibrous histioma
Predisposing factors to SCCSame as BCC
soft tissue tumors are of what origin
explosive onset of seborrheic keratosisleser, trelat, assoc with gastric adenocarcinoma
hairy brown patch, fake nevus
EIC on scalppilar cyst
Variant􏰀of􏰀SCC􏰀with􏰀sudden􏰀onset􏰀&􏰀rapid􏰀growthmay resemble BCC
Most􏰀common􏰀type􏰀of􏰀melanoma􏰀in􏰀dark􏰁skinned􏰀patients􏰀(AA);􏰀occurs􏰀on􏰀hands􏰀&􏰀feet; thick epidermis on feetAcral lentiginous melanoma, ALM
Characteristics Answerdetails
speckled patch acquired in childhoodbenign, but may degenerate to melanoma
precursor􏰀lesion􏰀to􏰀LMMfreckle, lentigo maligna
Melanoma with worst prognosis;minvasive􏰀in􏰀dermis without􏰀intra􏰁epidermal􏰀involvement
multiple􏰀small􏰀SK􏰀on􏰀malar􏰀area of􏰀face􏰀in􏰀darker􏰀skinVariant of SK, Dermatosis papulosa nigra
invasive proliferation􏰀of􏰀melanocytes􏰀into􏰀dermislentigo maligna melanoma
Best indicator of melanoma prognosisBreslow's thickness
common molejxnal, intradermal, compound
'in situ SCC'Associated􏰀with􏰀arsenic exposure􏰀&􏰀increased􏰀incidence􏰀of􏰀internal􏰀malignancy; has not invaded dermis yet (in-situ)
scaling,􏰀indurated,􏰀ulcerated􏰀nodule􏰀'sore􏰀that􏰀doesn't􏰀heal'; islands􏰀of􏰀neoplastic􏰀epidermal􏰀cells􏰀with􏰀'keratin􏰀pearls'; can metssquamous cell carcinoma
virus assoc with Kaposifound in AIDS (HIV)
halo nevi associated with what 2 conditions in adults
multiple internal fibromas; cafe au laitaka Von Recksomething
benign proliferation of squamous cellsseborrheic keratosis
#1 soft tissue tumor in adultsbenign
bcc with scar-like plaques, called 'infiltrative'morpheaform
frecklesmelanocytic
Bug in guttate psoriasisGroup A strep
brown􏰀macules (not􏰀raised!);􏰀confined􏰀to􏰀the􏰀epidermal􏰁dermal􏰀junctionnevus
fleshy,􏰀pedunculated,􏰀papillomatous􏰀lesions; central􏰀connective􏰀tissue􏰀core􏰀covered􏰀by􏰀epithelial􏰀cells􏰀(aka􏰀fibro􏰁epithelial􏰀polyp); 'skiacrochordon, benign, epithelial origin
single􏰀itchy 'herald􏰀patch' plaques􏰀on􏰀trunk; then multiple􏰀symmetrical eruptions􏰀with􏰀'Christmas􏰀tree'􏰀pattern; negative RPR and VDRL pityriasis rosea
Melanotic􏰀accumulation􏰀in􏰀mouth,􏰀lips,􏰀hands,􏰀genitalia; Polyps􏰀of􏰀colon􏰀&􏰀small􏰀intestine; ADpuetz jeghers
Characteristics Answerdetails
Predisposing factors to BCCSame as SCC
Multiple􏰀tiny􏰀white/yellow􏰀papules􏰀in􏰀newborns; variant of EIC, from diff part of hair follicle
Precursor􏰀lesion to􏰀malignant􏰀melanoma; flat at birth, thickens with agenevus
Which surfaces have psoriasis
organized brown􏰀nodules􏰀of􏰀fibroblasts􏰀invading􏰀the􏰀SC􏰀tissue (vs dermatofibroma, which stays in dermis, IE, is not malignant)dermatofibrosarcoma protuberans; malignant
Most􏰀common􏰀subtype of􏰀melanoma;􏰀occurs􏰀on􏰀trunk of􏰀men􏰀&􏰀posterior􏰀thigh of􏰀womensuperficial spreading melanoma
Well defined epidermal lesions with scales & symmetrical􏰀rashes (general term)PR, psoriasis, LP, LS, LN
Precursor􏰀lesion􏰀to􏰀SCC􏰀due􏰀to􏰀excessive􏰀exposure􏰀to􏰀sunlightactinic keratosis; squamous cell proliferation
Asymptomatic flesh􏰁colored􏰀papules􏰀(tiny􏰀bumps)􏰀that􏰀koebnerize; flexor􏰀surfaces of􏰀arms,􏰀trunk􏰀&􏰀penisLN
brown􏰀macules􏰀on􏰀sun􏰁exposed􏰀skin; limited melanocyte􏰀hyperplasia in􏰀basal epidermisage spots
rodent ulcer
melanocytic flesh􏰁colored papules􏰀(not􏰀pigmented!);􏰀confined􏰀to􏰀clusters􏰀within􏰀the􏰀dermisnevus
'pearly'􏰀papule􏰀with􏰀telangiectasia􏰀(dilated􏰀vessels); clusters􏰀of􏰀dark􏰀cells􏰀with􏰀palisading􏰀of􏰀nuclei; NO METSbasal cell carcinoma
lacy􏰀Wickham's􏰀striae
dome􏰁shaped dermal􏰀cyst􏰀(tumor􏰀containing􏰀liquid) with􏰀central􏰀puncta􏰀(opening)􏰀leaking􏰀cheesy􏰀 material; epithelial􏰀cyst􏰀(a􏰀real􏰀cystepidermal inclusion cyst, 'sebaceous cyst'
pigmented tumors of skin have what cellular originmelanocyte
retention of nuclei within the keratinosisparakeratosis; psoriasis
'slit􏰁like'􏰀spaces􏰀with􏰀RBC􏰀extravasation􏰀&􏰀hemosiderin􏰀deposition (greek men, HIV pts)HHV8
leser trelat assoc withor internal malignancy in general
Well􏰁defined,􏰀non􏰁itchy,􏰀red􏰀plaques􏰀(flat􏰀papules); Thick 'silvery􏰁white'􏰀scales􏰀&􏰀erythematous􏰀base

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