Science Quiz / Endocrine drugs

Random Science Quiz

QUIZ: Can you name the Endocrinology histology?

Quiz not verified by Sporcle

Challenge
Share
Tweet
Embed
Score 0/39 Timer 10:00
IndicationDrugContraindications, side effects and note
Precocious pubertyHeadache, depression, insomnia, nausea and vomiting
Kidney stones, idiopathic hypercalciuriaHypercalcemia
Paget's diseaseA cytotoxic antibiotic
Paget's disease, hyperparathyroidism, idiopathic juvenile hypercalcemia, vitamin D toxicosis, osteoporosisHypocalcemia, kidney stones
Paget's disease, osteoporosis, hypercalcemia of malignancyGastric irritation (abdo pain, diarrhea, loss of taste), bone pain, headache, rash
T2DM (by inhibiting carb absorption)Flatulence, diarrhea
Obesity (against fat absorption)Steatorrhea
Hyperparathyroidism, hypercalcemiaInhibit PTH synthesis at lower concentrations of calcium
T2DM (by blocking PPAR in adipocytes)Weight gain, possible liver disease and cardiac failure, bladder cancer
Osteoporosis, osteomalacia, rickets, hypoparathyroidismHypercalcemia, particularly dangerous in patients taking digoxin
T1DM (intermediate acting) Hypoglycemia, onset: 30 min, peak: 2h, lasts: 8h
HyperthyroidismDelayed hypothyroidism
T2DM (by blocking ATP-sensitive K channel)Weight gain, hypoglycemia, nausea, vomiting, alcohol-induced flushing
PCOS (hirsutism, by inhibiting binding of testosterone)Liver toxicity, gynecomastia, erectile dysfunction
Hyperthyroidism (more potent, crosses placenta)Cold dry skin, decreased pulse pressure, bradycardia, decreased appetite, fatigue, fever, rashes, jaundice, hepatitis, agranulocytosis
T1DM (long acting) Hypoglycemia, onset: 1hr, peak: 6h, lasts: 18h
T2DM (by blocking ATP-sensitive K channel, weakly)Weight gain, hypoglycemia, nausea, vomiting
Osteoporosis (for increasing bone mass)Very expensive
Myxedema coma, preparing for iodine therapyWarm moist skin, increased CO and pulse pressure, increased appetite, weakness
T2DM (by increasing insulin release)Expensive, by injection, also decreases appetite, gastric motility
IndicationDrugContraindications, side effects and note
HypoglycemiaSubcutaneous injection, can cause hyperglycemia
PCOS (for increasing fertility, via blocking estrogen inhibition of hypothalamus)Vasomotor flushing, visual blurring, ovary enlargement
T1DM (long acting) Hypoglycemia, onset: 4hr, peak: none, lasts: 18h
Obesity (against appetite)Depression, anxiety, nausea
Hypoaldosteronism, chronic adrenal insufficiencyHypokalemic alkalosis
HypothyroidismWarm moist skin, increased CO and pulse pressure, increased appetite, weakness
Hypothyroidism or hyperthyroidismHypothyroidism (via Wolff-Chaikoff effect) or hyperthyroidism, hyperthyroidism if used for >8 weeks (Jod Basedow phenomenon)
Obesity (against appetite)Increased heart rate, hypertension, sympathetic activation (dry mouth, constipation, nausea)
Hyperaldosteronism (Conn's syndrome)Hyperkalemia
T2DM (by reducing incretin degradation)Oral administration, decreases appetite with less effect
T2DM (by activating AMPPK)Lactic acidosis, anorexia, nausea, flatulence, diarrhea
Hyperthyroidism (less potent, does not cross placenta)Cold dry skin, decreased pulse pressure, bradycardia, decreased appetite, fatigue, fever, rashes, jaundice, hepatitis, agranulocytosis
Cortisol suppression tests, psoriasis, eczemaThinning skin
T1DM (short acting) Hypoglycemia, onset: 15 min, peak: 1h, lasts: 4h
PCOS (hirsutism, by blocking T to DHT conversion)Impotence
PCOS (hirsutism)Hyperkalemia
T1DM and T2DMWeight gain, hypoglycemia
Anything (adrenal crisis, chronic adrenal insufficiency)Cushingoid syndrome, edema, hypokalemic alkalosis, myopathy, induced ACTH insufficiency, reduced intestinal absorption of calcium
PCOS (hirsutism, by inhibiting binding of testosterone)Mild liver injury, GI

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.