Science Quiz / Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-intrinsic factor antibodies
Inversion c.16
Anti-endomysial IgA
Elevated tartrate-resistant acid phosphatase
Cause of liver angiosarcoma
PML/RARa gene created by
Anti-islet cell antibodies
CA 15-3 tumor marker
Auto-antiobdy seen in rheumatoid arthritis
CALLA is a positive indicator in...
S-100 tumor marker
Anti-SS-B (La) antibodies
Anti-histone antibodies
Auto-antibody seen in microscopic polyangiitis
Anti-MPO antibodies
Elevated bombesin
DCC mutation
High urinary HVA/VMA + N-Myc
Gene mutated in NF2
Gene mutated in MEN 2a/2b
Anti-microsomal antibodies
LDH tumor marker
Auto-antiobdy seen in drug-induced lupus
Anti-SCL 70 antibodies
Auto-antiobdy seen in seen in PBC
CA 125 tumor marker
Anti-voltage-gated Ca2+ channel antibodies
Anti-nuclear antibodies
Anti-tissue transglutiminase IgA
Ki67 fraction >99%
Inheritance of hereditary angioedema
AFP tumor marker
Anti-mitochondrial antibodies
HPV viral protein E6 target
Analine dyes
Anti-dsDNA antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in mixed connective tissue disease
Anti-LKM antibodies
Anti-Sm antibodies
Mutated in Li-Fraumani syndrome
Anti-smooth muscle antibodies
Rosenthal fibers
CA 19-9 tumor marker
Anti-Yo, Anti-P|Q, Anti-Hu
Homer-wright rosettes
Auto-antiobdy seen in CREST syndrome
Cells that stain (+) for synaptophysin
Pleomorphic astrocytes with brisk activity and necrosis
Defect in decay accelerating factor (DAF)
Gene involved in t(14;18)
Cystic brain tumor with granular eosinophilic bodies
Missing enzyme to degrade C3 and C4 convertase on RBCs
Deficiency of C1 esterase inhibitor
Anti-desmoglein antibodies
Anti-U1 RNP antibodies
Anti-ACh receptor antibodies
BCR-ABL fusion gene
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Auto-antiobdy seen in autoimmune hepatitis
Auto-antiobdy seen in polymyositis
Causes centrilobular necrosis and fatty change of the liver
Mutated in familial adenomatous polyposis
CEA tumor marker
HPV viral protein E7 target
MCC1 complement deficiency
Anti-TSH receptor antibodies
Growth factor affected by osteosarcoma
Receptor targeted by tratuzumab
N-MYC implicated in what cancer
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-centormere antibodies
Spindle cells with hair-like glial processes
CD10 is a positive indicator in...
ERB-B2 gene
Anti-SS-A (Ro) antibodies
Anti-giladin IgA
Anti-IgG antibodies
Anti-GBM antibodies
Auto-antiobdy seen in Grave's disease
Anti-proteinase 3 antibodies
Auto-antibody seen in Wegener's granulomatosis
AD mutation of NF1
Cancer of CyclinD dysregulation
t(8;14) affects what gene
Anti-DNA topoisomerase 1 antibodies
What is translocation of mantle cell lymphoma?
Anti-ribonucleoprotein antibodies
Tumor marker for neuroblastoma
Anti-Jo-1 antibodies
DPC mutation
Thorotrast, arsenic, polyvinyl chloride
AD mutation in p53 gene
Anti-parietal cell antibodies
C-MYC implicated in what cancer
HVA in urine
Gene is involved in t(11;14)
Auto-antiobdy seen in Goodpasture syndrome
AD mutation in APC gene
c-Myc activating cancer leads to EWSFL1 over-production
Anti-glutamate decarboxylase antibodies
Anti-thyroperoxidase antibodies
Pseudorosettes with GFAP positive processes
Anti-insulin antibodies
AD mutation in MLH1/MSH2
Anti-thyroglobulin antibodies

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker

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