Science Quiz / Goljan 4 of X: Glomerular Disease

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Can you name the Goljan 4 of X: Glomerular Disease

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HintAnswer
MCC1 post-infectious GN
Sub-endothelial IC despots with granular IF
Rheumatoid arthritis + nephrotic syndrome
HCV + nephrotic syndrome
Term meaning thickened GBM w/o proliferation
MCC1 GN in heroin abuse
Crescentic proliferation is an expansion of what cells?
Term meaning parietal epithelial cell proliferation
Hematuria 2-3 days after URI
JGA produces...
Maximum proteinuria for nephritic syndrome
Glomerular capillaries damaged by buildup of...
Coarse granular sub-epithelial deposits of IgG and C3
Hypercellular nuclei and (+)ASO
LM shows nodular glomerulosclerosis with mesangial expansion and nodular thickening
Hematuria 2-3 weeks after URI
Term meaning thickened GBM w/ hyper cellular glomeruli
What structure retains albumin in the glomerulus?
Minimum proteinuria for nephritic syndrome
Most common form of MPGN
MCC1 GN in young black males
Associated with C3 nephritic factor
Sclerosis = build up of...
Diffuse intra-membranous deposits with tram-tracking
MGN appears similar to what nephritic syndrome on EM/IF
Congo red stain
Cause of hyper coagulability in nephrotic syndrome
EM shows splitting of GBM by ingrowing mesangium
Extremely low C3 levels
Inheritance of benign familial hematuria
Increased serum IgA + focal proliferative GN
MCC1 renal failure in the US
Fatty casts with maltese crosses
Purpuric lesions of skin + abdominal pain + hematuria
Afferent arteriole flow controlled by...
Cryoglobulinemia + nephrotic syndrome
HintAnswer
Fibrosis = build up of...
Episodic hematuria + premature HTN + s/p upper respiratory infection
HBV + nephrotic syndrome
MCC2 nephrotic syndrome in adults
Diffuse thickening of membranes with sub-epithelial ICs
Tram-tracking on EM
Antigen associated with MGN
'Wire-looping' of capillaries with hyaline thrombi
Negative IF with podocyte fusion on EM
Sub-endothelial ICs with granular IF + nephrotic syndrome
Lipid accumulation in visceral epithelial cells
Dense deposit disease
PLA2R IgG4 antibodies
'Rim pattern' of serum ANA
T-cell cytokine destruction of GBM
Associated with Ab against C3-convertase
Diffuse proliferative GN + sub-endothelial ICs
Diffuse proliferative GN + sub-epithelial ICs
Nodular masses in the mesangial matrix + hyaline arteriolosclerosis
Sub-endothelial ICs, granular IF, tram-tracking
Begins with hemoptysis, rapid progression to renal failure
Deposits of this cause linear pattern on IF
Non-enzymatic glycosylation of the GBM
JGA found in what structure?
Minimum proteinuria for nephrotic syndrome
Mutated in Alport syndrome
Glomerular basement membrane produced by...
Focal proliferative GN with mesangial Ig deposits and granular IF
Multiple myeloma + nephrotic syndrome
Positive anti-cationic proteinase with low C3
Sub-epithelial ICs + granular IF + nephrotic
Linear IF without electron dense deposits
Most common inheritance of Alport syndrome
Titer seen in PSGN
Negative IF with focal damage of visceral epithelial cells
GBM made of what type of collagen
HintAnswer
Anti-GBM antibodies against T4C
MCC1 nephrotic syndrome in children
Treatment for minimal change disease
RPGN + p-ANCA
Nerve dz + ocular dz + deafness
Infection in nephrotic syndrome
Crescent of fibrin and c3b with linear IF
Apple-green birefringence
MCC1 chronic glomerulonephritis
Sub-epithelial IC deposits with granular IF + Nephritic
RBC casts are pathognomonic for
Anatomic area of the kidney susceptible to ischemia
Sub-endothelial DNA-anti-DNA ICs
RPGN + c-ANCA
MCC2 chronic glomerulonephritis
MCC1 normotensive nephrotic syndrome
'Spike and dome' on silver stain beneath VECs
Gold therapy predisposes to...
MCC1 death in SLE
Diffuse proliferative GN with neutrophil infiltration
Secondary cause of minimal change disease
Diffuse capillary-GBM thickening with spike and dome sub-epithelial ICs
MCC1 nephrotic syndrome in adults
Foam cells in glomerulus
 
MCC1 GN in HIV+ status
Initial manifestation of diabetic kidney Dz
Hyaline arteriolosclerosis prefers this structure
'Lumpy bumpy' glomeruli on LM with sub-epithelial humps and granular IF + nephritic proteinuria
Mesangial Ig deposits with granular IF
Treatment for FSGS
Efferent arteriole flow controlled by...
Nose bleeds + hematuria + glomerulonephritis
Deposits of this cause granular pattern on IF
Sorbitol is formed by what enzyme

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Created Jan 6, 2014ReportNominate
Tags:disease

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