Science Quiz / BCM Block 7 Renal

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Can you name the BCM Block 7 Renal?

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hintanswerextra fun facts
name a cause of non-anion gap metabolic acidosis
MCC ESRD; progresses from hyper-filtration to GBM thickening to microalbuminurea to NS to ESRD
otherwise healthy person collapses/presents with neurologic dysfunction after running a marathon. give H20 (D5W), 0.9%m NaCl, or 3% NaCl??
nephritic syndrome of older men with no IF pathology or EM pathology (aside from GBM gap), caused by a type III hypersensitivity
person comes in with rash, eosinophilia, fever 2 wks after introduction to a new drug (This is AIN, a type of TIN). name one of the causative drugz
nephrotic syndrome, T-cell derived circulating factor causes damage to podocytes; no IF findings; tends to recur
name the syndrome: global or nodular mesangial sclerosis, thicking of glomerular & tubular GBM (leading to effacement of foot proceses & tubular atrophy), hyalinosis of renal ateri
pt is vomiting. expected resultant acid/base disturbance?
so, amphoteracin B causes RTA type I (distal hypokalemic), bactrim causes type IV (distal hyperkalemic). which of our diuretics causes type II (proximal hypokalemic)?
syndrome caused by gain of function mutation leading to HTN, hypokalemia, metabolic alkalosis, low renin, low aldosterone
pH 7.30, Na 139, K+ 3.9, Cl 104, HCO3 10. what do you expect PaCO2 to be?
potassium sparing diuretics act distally (cortical collecting duct) and block aldosterone's habit of dumping K+ for Na+. amiloride and bactrim inhibit ENaC. Who antagonizes aldoste
nephritic syndrome with mesangial deposits/proliferation, slow progression, poor prognosis
hintanswerextra fun facts
first line drug class for DM nephropathy
nephrotic syndrome, circulating factor directly damages podocytes, HIV/heroin association, IgM & c3 trapped in glomerulus
like math? pH 7.29, Na 140, K 4.1, Cl 104, HCO3 12. AG = ??
pH 7.56, Na 141, K+ 4.1, Cl 105, HCO3 26, PaCO2 60, PaO2 70. acute or chronic respiratory acidosis?
most sensitive test for pheochromocytoma
presents with Pressure (HTN), pain (HA), perspiration, palpitation, pallor, paroxysm
older gentleman with weak stream progressing to oliguria/anuria. FeNA high or low?
nephritic syndrome caused by type II hypersensitivity to collagen type IV, linear IgG and C3 deposits
nephrotic syndrome, older men, type II hypersensitivity to phospholipase A2 on podocytes; granular IgG/C3, subepithelial deposits
lumpy bumpy IgG & C3, subepithelial humps, nephritic syndrome
AKI: FENa less than 1%, BUN/creatinine greater than 20. pre-renal, renal, or post-renal?
nephrotic syndrome in young women, circulating immune complex, tram tracking IgG/C3, subendothelial deposits, mesangial interposition, HCV
this hormone causes the insertion of ENaC's into apical membrane in cortical collecting duct principal cells.

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