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Science Quiz / NSAIDS, DMARDS, Anti Gout

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Can you name the NSAIDS, DMARDS, Anti Gout?

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YearDrugs
Biologic DMARD: blocks CD80 and 86, prevents T cell activation
Tx prophylaxis of recurrent episodes of gouty arthritis and Mediterranean fever (NSAIDs have replaced for acute gout to avoid diarrhea): inhibits microtubule polymerization, preven
Biologic DMARD: monoclonal against CD20 B lymphocytes
Pulm. Hyperten, inh. Plat. agg.
Pulm. Hyperten
Anti-gout: prevents reabsorption of uric acid in proximal tubule.
Anti-gout: inhibits xanthine oxidase prevents urate formation
Anti-gout: inhibits xanthine oxidase prevents urate formation
PGE1 analog (agonist to both EP2 and EP3 receptors) Gastric cytoprot., obst.- (abortificatient), patent ductus arteriosus, asthma
Leukotriene receptor antagonist. Clinical use asthma
PGF2alpha analogs decrease intraocular pressure via vasoconstriction of uveasclera blood vessels. Ophthalmology (glaucoma)
PGE1 agibust: Clinical use--erectile dysfunction, Patent ductus arteriosus
inhibit formation of leukotriene (lipooxygenase inhibitor). Clinical use--Asthma
PGE2 analog binds EP2 and EP3 receptors. EP3 receptor activation in uterus causes contractions. Obstetric use: cervical ripening and uterine contractions
PGF2alpha analogs decrease intraocular pressure via vasoconstriction of uveasclera blood vessels
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