Science Quiz / NSAIDS, DMARDS, Anti Gout

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Can you name the NSAIDS, DMARDS, Anti Gout?

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YearDrugs
Anti-gout: inhibits xanthine oxidase prevents urate formation
Leukotriene receptor antagonist. Clinical use asthma
Anti-gout: inhibits xanthine oxidase prevents urate formation
Anti-gout: prevents reabsorption of uric acid in proximal tubule.
Biologic DMARD: blocks CD80 and 86, prevents T cell activation
PGE1 agibust: Clinical use--erectile dysfunction, Patent ductus arteriosus
Tx prophylaxis of recurrent episodes of gouty arthritis and Mediterranean fever (NSAIDs have replaced for acute gout to avoid diarrhea): inhibits microtubule polymerization, preven
Pulm. Hyperten
PGE2 analog binds EP2 and EP3 receptors. EP3 receptor activation in uterus causes contractions. Obstetric use: cervical ripening and uterine contractions
PGF2alpha analogs decrease intraocular pressure via vasoconstriction of uveasclera blood vessels
Biologic DMARD: monoclonal against CD20 B lymphocytes
Pulm. Hyperten, inh. Plat. agg.
PGF2alpha analogs decrease intraocular pressure via vasoconstriction of uveasclera blood vessels. Ophthalmology (glaucoma)
PGE1 analog (agonist to both EP2 and EP3 receptors) Gastric cytoprot., obst.- (abortificatient), patent ductus arteriosus, asthma
inhibit formation of leukotriene (lipooxygenase inhibitor). Clinical use--Asthma

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