Science Quiz / Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Liver angiosarcomaenvironmental
Sporadic Breast Cancergene overexpression
Renal cancergene mutation, in adults
Some leukemias and lymphomasinherited syndrome
Familial polyposis coligene mutation
Acute Leukemiaenvironmental
T Cell leukemiavirus
T Cell neoplasmsGene overexpression
Hepatocellular carcinomaenvironmental
Kaposi's Sarcoma (in AIDS)virus
Leukemias, thyroid, bone cancersenvironmental/occupational
Liver cancertoxin from Aspergillus
Li-Fraumeni Syndromegene mutation
Gastric cancerbacteria
Cervical CancerHPV types
Familial melanomaGene mutation
Mantle Cell lymphomat(11;14), overexpress cyclin
Cancer CausedGenes/EffectorsHints
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Nasopharyngeal Cancersvirus
Follicular Lymphomat(14;18)
Transcriptional Activationgeneral oncogene
Lung and Skin cancersenvironmental
Burkitt Lymphomavirus
Neurofibromatosis Type 1gene mutation
Cervical CancerHPV genes
Wilm's Tumorgene mutation, in kids
Familial Breast Cancer, OvarianGene mutation
Hepatocellular CarcinomaResult of HBV liver damage
Some immunodeficiency statesgene mutation
Retinoblastomagene mutation
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Hereditary nonpolyposis colon cancermismatch DNA repair

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