Science Quiz / Hem/Onc Pharm

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Can you name the Hem/Onc Pharm?

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QuestionAnswerNotes
Cilostazol/dipyridamole inhibit:
Testosterone receptor antagonist
Aromatase stored in?
Cytokine to treat melanoma, renal cell carcinoma
Bortezxomid is used to treat?
Purine analog metabolized by xanthine oxidase
Mech of cisplatin
GnRH antagonist, no flare phenomenon
Prevent Hematuria with R-CHOP
SE avoided with lepirudin and bivalirudin
Rx that inhibits ribonucleotide reductase
SE: abciximab
SE: cyclophosphamide
Tamoxifen is an antagonist only in?
Adverse effect of tamoxifen
Antibody in Rituximab: anti-?
SE of vinblastine
Inhibits DNA polymerase
Anti-metabolites phase of action?
Activates 6-MP (purine analog)
Mechanism: irreversible acetylation
Rx to prevent hemorrhagic cystitis
Filgrastim, sargramostim used to help?
SE of methotrexate
Inhibits adrenal and testicular androgen synthesis
Iron chelator
SE of Trastuzumab/Herceptin
QuestionAnswerNotes
Antidote: warfarin (besides vit K)
Taxanes prevent microtubule?
Great drug for solid tumors
5-Fluorouracil inhibits
Tx: colon, non-small cell lung, breast cancer
Class: anastrozole, exemestane
SE: Osteoporosis and thromboembolism
OD: anion gap metabolic acidosis with respiratory alkalosis
Warfarin-induced skin necrosis - deficiency of?
Key use of 5-FU
Unique SE of flutamide
Lab to differentiate folate/B12 deficiency
SE of Taxanes
Tx: tumor lysis syndrome (besides hydration)
Class: Bevacizumab
Test to monitor warfarin
Class that crosses the BBB?
SE of bleomycin
SE of vincristine
Phase of microtubule inhibitors
Rx w/ inc toxicity with allopurinol
Test to monitor heparin
OK in pregnancy: heparin or warfarin
Rx increases plasmin
Irinotecan/topotecan inhibit?
Antidote: heparin
Methotrexate inhibits
QuestionAnswerNotes
Etoposide
Tx OD of 5-FU
SE: Nephrotoxicity, ototoxicity, nausea
Activates antithrombin III
Tx OD of methotrexate
Antidote: tPA
No myelosuppression (but lung SE)
Antibody against GP IIb/IIIa receptor
Raloxifene is an agonist only in?
Interleukin used to help thrombocytopenia
Which class? cyclophosphamide, ifosfamide
Antibody in Trastuzumab: anti-?
GnRH agonist, dec LH and FSH
Hemorrhagic cystitis w/ alk. agents due to buildup of?
Class: Bortezxomib
SE of doxorubicin
clopidogrel/ticlopidine block ? receptors
SE of busulfan?
Cytarabine is analog of
Class: carmustine, lomustine, Streptozocin
Vinca alkaloids prevent microtuble?
Warfarin blocks which enzyme
Cytokine used to treat melanoma, kaposi's sarcoma
Rituximab used to treat?
Allopurinol given to leukemia pt to prevent?
Use of busulfan?
Tx: HIT

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Created Aug 24, 2012ReportFavoriteNominate

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