Science Quiz / Hem/Onc Pharm

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Can you name the Hem/Onc Pharm?

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QuestionAnswerNotes
Test to monitor heparin
Tx: HIT
Cytarabine is analog of
SE of Trastuzumab/Herceptin
SE of Taxanes
SE: Nephrotoxicity, ototoxicity, nausea
Rituximab used to treat?
Class: carmustine, lomustine, Streptozocin
Testosterone receptor antagonist
Antibody in Trastuzumab: anti-?
SE of vinblastine
GnRH agonist, dec LH and FSH
Allopurinol given to leukemia pt to prevent?
SE: Osteoporosis and thromboembolism
Taxanes prevent microtubule?
Unique SE of flutamide
SE: cyclophosphamide
Lab to differentiate folate/B12 deficiency
Phase of microtubule inhibitors
Test to monitor warfarin
Cytokine used to treat melanoma, kaposi's sarcoma
Filgrastim, sargramostim used to help?
Prevent Hematuria with R-CHOP
Rx increases plasmin
Rx to prevent hemorrhagic cystitis
OD: anion gap metabolic acidosis with respiratory alkalosis
Vinca alkaloids prevent microtuble?
QuestionAnswerNotes
Adverse effect of tamoxifen
Rx that inhibits ribonucleotide reductase
Class: anastrozole, exemestane
Key use of 5-FU
OK in pregnancy: heparin or warfarin
Warfarin blocks which enzyme
Cilostazol/dipyridamole inhibit:
Mech of cisplatin
Raloxifene is an agonist only in?
Which class? cyclophosphamide, ifosfamide
Hemorrhagic cystitis w/ alk. agents due to buildup of?
Antidote: tPA
Interleukin used to help thrombocytopenia
Etoposide
Tx: tumor lysis syndrome (besides hydration)
Warfarin-induced skin necrosis - deficiency of?
Antibody against GP IIb/IIIa receptor
Tx: colon, non-small cell lung, breast cancer
SE of doxorubicin
Inhibits adrenal and testicular androgen synthesis
SE of busulfan?
Irinotecan/topotecan inhibit?
Anti-metabolites phase of action?
Antidote: heparin
Class that crosses the BBB?
Tx OD of 5-FU
Iron chelator
QuestionAnswerNotes
SE of vincristine
Antibody in Rituximab: anti-?
SE of methotrexate
Tamoxifen is an antagonist only in?
Inhibits DNA polymerase
Activates antithrombin III
Aromatase stored in?
Cytokine to treat melanoma, renal cell carcinoma
Purine analog metabolized by xanthine oxidase
Bortezxomid is used to treat?
GnRH antagonist, no flare phenomenon
Antidote: warfarin (besides vit K)
Class: Bevacizumab
SE avoided with lepirudin and bivalirudin
5-Fluorouracil inhibits
Rx w/ inc toxicity with allopurinol
SE: abciximab
Activates 6-MP (purine analog)
Mechanism: irreversible acetylation
Class: Bortezxomib
SE of bleomycin
Use of busulfan?
clopidogrel/ticlopidine block ? receptors
Great drug for solid tumors
Tx OD of methotrexate
Methotrexate inhibits
No myelosuppression (but lung SE)

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Created Aug 24, 2012ReportNominate

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