Science Quiz / Block 8a Tissues

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Can you name the Block 8a Tissues?

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scleroderma limited to skin of fingers and face
migration of embryotic lines during development
Rx causing celecoxib levels to rise
fludrocortisone is tx for?
Rx: works where cyclosporin fails
localized thickening and tightness of the skin of fingers or toes
autoimmune dz w/ popped blistering
Nevus assoc w/ vitiligo and metastatic melanoma
triangle filled w/reactive bone (osteosarcoma)
Pityriasis Rosea starts with
Acanthosis, parakeratosis, loss of granular layer
class: principally salt-retaining activity
only NSAID approved for parenteral admin
Rash with relative central clearing and active peripheral border
increased vascular pedicle width
palpable purpuric lesion after PCN
Inflammatory reaction to yeast Pityrosporum
Usu location of Ewing's sarcoma
Apple core lesion in colon - MC?
fluid leakage into peripheral interlobular septa
Herpes Simplex on finger
TH1 or TH2: eczema
Organism in Acute Paronychia
Syndrome assoc w/ capillary malformation in V1
Decade that IR was born
target lesions, classically
Antiphospholipid syndrome - ab against?
thick 'silvery white scale'
TH1 or TH2: psoriasis
Rx for acute gout: inhibits PMN microtubule assembly
Rx for SJS
radiography for vascular/aortic injury
only selective NSAID on the market
ending of selective NSAIDs
MC form of oral LP
Superficial cellulitis, Group A Strep, well demarcated, usu face
ephelides, aka ?
Salmon/white/brown rash on back/chest in summer months
basilar vacuolation/hydropic degeneration of stratum basalis
Rx class: lanosterol demethylase
scalp lesion but different part of follicle c/w epidermal incl cyst
antidote for acetaminophen OD
diffuse scleroderma - spec antibody to ?
Firm, violaceous color due to Kasabach-Merritt phenomenon
honey colored crust by kid's mouth
something in elbow pushes ? posteriorly
Rx: Bind/cross-links DNA to block synthesis
hyperkeratosis, hypergranulosis, acanthosis
hyperparpathyroid & hypothyroid decrease uric acid ?
Virus assoc w/ lichen planus
Candida - groin, axilla, inframammary
intertiginous red streaks in scarlet fever
non-purine selective inhibitor of xanthine oxidase
internal neurofibroma, cafe-au-lait spots
autoimmune dz w/ intact bullae
Uniform, flesh colored papules that koebnerize
localized linear scleroderma
limited scleroderma - spec antibody to ?
Large deep Staph Aureus abscesses
ERCP that has 10% chance of causing ?
MC soft tissue tumor of adulthood
visible under LM with alizarin red staining
Rx: Reverses altered keratinization
Deep sulcus sign on radiograph
Explosive onset of pruritic SKs - sign of?
Corynebacterium minitussimum
Lesion called burrow
Rate limiting step of purine metabolism
Gold standard test: fungi in skin hair and nails
mucuous membrane involvement is hallmark in which skin reaction?
hemangiomas of infancy are positive for?
Bright red, satellite pustules
Meniscus sign on radiograph
Tx for secondary adrenal insufficiency
Hemorrhage, Edema, Aspiration, Pneumonia
malignant melanocytic cells; go up into dermis
'Rat bite' erosions may be seen when ? are present on xray
Which? Tip b/t main PA and bilateral pulm hila
Enzyme b/t inosinic acid and hypoxanthine
wheals - due to release of?
Hypoxemia & etoh tox ? urate reabsorption
MC crystal in BCP deposition disease
flat lesion
lesion goes through dermis & epidermis
buckling of cortex
papillomatosis, perinuclear halo, prominent keratohyaline
MC neuro sx w/ lupus
most damaging/limiting effect of long term steroids
inhibit platelet aggregation - only rec. use of?
In PV, autoantibodies are against ?
MC location for osteosarcoma
? predisposes to CPPD deposition diseases
classification system - fx wrt growth plate
Rx class: inh beta-1,3 glucan synthesis
Steroid class: dexamethasone/triamcinolone
Candida - labial commissure
Umbilicated papules and pox virus
skin tags, aka ?
MC malignant tumor in young adults
'atypia is not full thickness'
Syndrome assoc w/ prox coarctation of the aorta
muscle biopsy: inflammation and necrobiotic degeneration
proximal muscle weakness and light sensitive rash
Facial nerve involvement with Zoster
MCC: large joint (ie shldr) destructive arthritis
Dose limiting SE of cyclosporin
Mortality in scleroderma assoc w/ ?
small fluid filled lesion
Anti-La (SS-B) and Ro also present in ?
MC electrolyte change with Lung SCC
false + test for treponema pallidum (and +ANA)
PV or BP: Subepidermal blisters and linear BM IF
protein mutation in atopic dermatitis
lichen planus: white reticulated pattern on top
Most severe SE from steroid withdrawal
Aspirin effect on warfarin
exudate filled lesion
Central facial erythema/telangiectasia
Antigen assoc w/ most serious dz in polymyositis
Rx: correct acid-base imbalance with ASA OD
Dx: dec re-utilization of purine bases in the salvage pathways
induced by glucocorticoids to suppress phospholipase A2
Syndrome assoc w/ Complex Vascular Malformation
Type of necrosis in vasculitis
papillomatosis and horn pseudocyst
MC SE from steroid withdrawal
Koebner's phenomenon occur in areas of?
clefting artifact, myxoid stroma
human mab: BLyS-specific inhibitors
Rx: block memory B cells and inh lymphocyte proliferation
ACTH excess
estogen replacement therapy risk for?
'net like'
Angel wing deformity of nails
'atypia is full thickness'
lesion raised less than 1/2cm
leathery skin in bilateral, diffuse, distal areas
Primary lesion of acne
skin cond: steroid withdrawal may cause?
sv dermal effect assoc w/ inhibition of prostaglandin synth
Erythematous raised patches w/ adherent keratotic scaling and follicular plugging
Tip of PICC at junction of SVC and ?
Rx causing hyperuricemia
swelling of liver/brain with ASA
Linear dermatosis, primarily affects children
Which? Tip 3-5 cm above the carina
hyperplasia/thickening of stratum spinosum
First joint affected in gout
arborizing vascular network; cellular lipocytes w/ “chicken wire” vessels
lentigines on lips/oral mucosa, abd pain
psoriasis usu on which surfaces
Steroids tx autoimmune hemolytic anemia assoc w/ ?
lesion assoc w/ HHV-8
Rx: FKBP binds/inh mTOR, low nephrotoxicity
acanthosis w/ basal hyperpigmentation
Rx: Raynaud's
Type of arthritis in lupus
IR tx for liver HCC
MC skin cancer
Candida - nail cuticle
Hydralazine and minocycline both cause?
zoophilic variant of tinea corporis
Earliest symptom of malignant melanoma
MCC of Morbilliform rash
Mult epidermal incl cysts, osteomas, fibromas, lipomas
LAH and RBBB most common EKG findings in?
hyperplasia/thickening of stratum corneum
Anuclear hyperkeratosis
Enteric tube with metal, weighted tip
XR: periarticular deposits of apatite
gold standard for dx of allergic contact dermatitis
LM: intracellular calcium pyrophosphate dihydate (CPPD) crystals
intraarticular = ___physeal
fracture of cortex
“coin shaped” eczema
Anti-Ro (SS-A) assoc w/ ? in newborn babies
Hyperkeratosis that retains nuclei
Dz: linear nodules along lymphatics
MC joint affected in pseudogout
acetic acid derivative that dec arachidonic acid
supracondylar = ___physeal
midshaft = ___physeal
hyperpigmented rete ridges (path)
guttate psoriasis after infection w/ ?
'dew drop on a rose petal'
deposits of monosodium urate (MSU) crystals
Test w/ negative predictive value 95% for lupus
Codman triangle, sunburst pattern
PV or BP: Suprabasal acantholytic blister
loss of intercellular bridges of stratum spinosum
Irregular metaphyseal corners assoc w/ ?
Dogs/cats dont get gout b/c they have ?
Coral red fluorescence (Woods lamp)
PR like eruption on palms and soles
Bowen's dz - ? in situ
serum urate conc > 6.8 mg/dL
Drug induced acute, generalized skin eruption
premies at risk for which skin condition?
100% specific for SLE, but only found in 25-30%,
Thickness from top of granular layer to bottom of deepest lesion
When pos, titer useful for monitoring lupus activity
Usu bacteria in Furuncle
reddish-white and shiny lesions on extensor surface, joints of hands
bridging, lamellar fibrosis, atypical melanocytes
brown patch on shldr that grows hair @ puberty
Batwing appearance
Rx: bone marrow and GI toxic, hepatic fibrosis and cirrhosis
Long glucocorticoid duration - low or high 11β-HSD II binding affinity?
arterial and venous thromboses, spont abortions, and low platelets
Endocarditis assoc w/ lupus
Pruritic, purple polygonal papules
eczema usu on which surfaces
Rx class: squalene epoxidase
Scarlet fever organism
sandwich sign (path)
MAb to prevent acute phase rejection

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