Science Quiz / Block 8a Tissues

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QUIZ: Can you name the Block 8a Tissues?

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fludrocortisone is tx for?
Irregular metaphyseal corners assoc w/ ?
autoimmune dz w/ intact bullae
Acanthosis, parakeratosis, loss of granular layer
most damaging/limiting effect of long term steroids
Tx for secondary adrenal insufficiency
'net like'
papillomatosis, perinuclear halo, prominent keratohyaline
lichen planus: white reticulated pattern on top
Antigen assoc w/ most serious dz in polymyositis
hyperpigmented rete ridges (path)
Candida - labial commissure
non-purine selective inhibitor of xanthine oxidase
PR like eruption on palms and soles
Mult epidermal incl cysts, osteomas, fibromas, lipomas
MCC of Morbilliform rash
bridging, lamellar fibrosis, atypical melanocytes
'atypia is full thickness'
Apple core lesion in colon - MC?
Dose limiting SE of cyclosporin
Usu bacteria in Furuncle
'atypia is not full thickness'
MC form of oral LP
100% specific for SLE, but only found in 25-30%,
Usu location of Ewing's sarcoma
only selective NSAID on the market
small fluid filled lesion
Aspirin effect on warfarin
PV or BP: Suprabasal acantholytic blister
Rx: Bind/cross-links DNA to block synthesis
scalp lesion but different part of follicle c/w epidermal incl cyst
MC malignant tumor in young adults
something in elbow pushes ? posteriorly
Anti-La (SS-B) and Ro also present in ?
Test w/ negative predictive value 95% for lupus
Rx class: inh beta-1,3 glucan synthesis
hyperkeratosis, hypergranulosis, acanthosis
Drug induced acute, generalized skin eruption
Rx: block memory B cells and inh lymphocyte proliferation
Rx: FKBP binds/inh mTOR, low nephrotoxicity
mucuous membrane involvement is hallmark in which skin reaction?
Salmon/white/brown rash on back/chest in summer months
Hypoxemia & etoh tox ? urate reabsorption
papillomatosis and horn pseudocyst
Pityriasis Rosea starts with
fracture of cortex
MC soft tissue tumor of adulthood
limited scleroderma - spec antibody to ?
basilar vacuolation/hydropic degeneration of stratum basalis
autoimmune dz w/ popped blistering
increased vascular pedicle width
Rx: correct acid-base imbalance with ASA OD
Type of necrosis in vasculitis
'dew drop on a rose petal'
estogen replacement therapy risk for?
palpable purpuric lesion after PCN
Syndrome assoc w/ prox coarctation of the aorta
leathery skin in bilateral, diffuse, distal areas
Explosive onset of pruritic SKs - sign of?
supracondylar = ___physeal
Enteric tube with metal, weighted tip
deposits of monosodium urate (MSU) crystals
ending of selective NSAIDs
ACTH excess
intertiginous red streaks in scarlet fever
thick 'silvery white scale'
Rx class: lanosterol demethylase
Candida - groin, axilla, inframammary
Decade that IR was born
Large deep Staph Aureus abscesses
Organism in Acute Paronychia
Firm, violaceous color due to Kasabach-Merritt phenomenon
Dz: linear nodules along lymphatics
Rx class: squalene epoxidase
swelling of liver/brain with ASA
Which? Tip b/t main PA and bilateral pulm hila
only NSAID approved for parenteral admin
lentigines on lips/oral mucosa, abd pain
target lesions, classically
Virus assoc w/ lichen planus
arborizing vascular network; cellular lipocytes w/ “chicken wire” vessels
induced by glucocorticoids to suppress phospholipase A2
hemangiomas of infancy are positive for?
sv dermal effect assoc w/ inhibition of prostaglandin synth
false + test for treponema pallidum (and +ANA)
internal neurofibroma, cafe-au-lait spots
MC SE from steroid withdrawal
gold standard for dx of allergic contact dermatitis
When pos, titer useful for monitoring lupus activity
radiography for vascular/aortic injury
Lesion called burrow
MC electrolyte change with Lung SCC
muscle biopsy: inflammation and necrobiotic degeneration
premies at risk for which skin condition?
Erythematous raised patches w/ adherent keratotic scaling and follicular plugging
Angel wing deformity of nails
LAH and RBBB most common EKG findings in?
MAb to prevent acute phase rejection
Meniscus sign on radiograph
Rate limiting step of purine metabolism
Pruritic, purple polygonal papules
Rx for SJS
scleroderma limited to skin of fingers and face
ERCP that has 10% chance of causing ?
Gold standard test: fungi in skin hair and nails
“coin shaped” eczema
class: principally salt-retaining activity
In PV, autoantibodies are against ?
psoriasis usu on which surfaces
MC skin cancer
eczema usu on which surfaces
Syndrome assoc w/ capillary malformation in V1
Thickness from top of granular layer to bottom of deepest lesion
Deep sulcus sign on radiograph
clefting artifact, myxoid stroma
ephelides, aka ?
hyperparpathyroid & hypothyroid decrease uric acid ?
Scarlet fever organism
Tip of PICC at junction of SVC and ?
arterial and venous thromboses, spont abortions, and low platelets
Long glucocorticoid duration - low or high 11β-HSD II binding affinity?
brown patch on shldr that grows hair @ puberty
acanthosis w/ basal hyperpigmentation
midshaft = ___physeal
human mab: BLyS-specific inhibitors
honey colored crust by kid's mouth
Steroid class: dexamethasone/triamcinolone
Hydralazine and minocycline both cause?
Steroids tx autoimmune hemolytic anemia assoc w/ ?
Koebner's phenomenon occur in areas of?
MCC: large joint (ie shldr) destructive arthritis
Rx for acute gout: inhibits PMN microtubule assembly
lesion raised less than 1/2cm
Candida - nail cuticle
Endocarditis assoc w/ lupus
Codman triangle, sunburst pattern
Hyperkeratosis that retains nuclei
Herpes Simplex on finger
reddish-white and shiny lesions on extensor surface, joints of hands
localized thickening and tightness of the skin of fingers or toes
Dogs/cats dont get gout b/c they have ?
IR tx for liver HCC
Superficial cellulitis, Group A Strep, well demarcated, usu face
inhibit platelet aggregation - only rec. use of?
Dx: dec re-utilization of purine bases in the salvage pathways
Corynebacterium minitussimum
LM: intracellular calcium pyrophosphate dihydate (CPPD) crystals
Umbilicated papules and pox virus
Uniform, flesh colored papules that koebnerize
? predisposes to CPPD deposition diseases
XR: periarticular deposits of apatite
Mortality in scleroderma assoc w/ ?
lesion goes through dermis & epidermis
malignant melanocytic cells; go up into dermis
zoophilic variant of tinea corporis
Primary lesion of acne
MC location for osteosarcoma
Batwing appearance
Anuclear hyperkeratosis
First joint affected in gout
protein mutation in atopic dermatitis
migration of embryotic lines during development
TH1 or TH2: psoriasis
antidote for acetaminophen OD
MC crystal in BCP deposition disease
Linear dermatosis, primarily affects children
Bowen's dz - ? in situ
exudate filled lesion
MC joint affected in pseudogout
Central facial erythema/telangiectasia
Antiphospholipid syndrome - ab against?
fluid leakage into peripheral interlobular septa
Rx: Raynaud's
acetic acid derivative that dec arachidonic acid
Type of arthritis in lupus
Rx causing hyperuricemia
Syndrome assoc w/ Complex Vascular Malformation
flat lesion
Facial nerve involvement with Zoster
Inflammatory reaction to yeast Pityrosporum
diffuse scleroderma - spec antibody to ?
lesion assoc w/ HHV-8
skin cond: steroid withdrawal may cause?
Hemorrhage, Edema, Aspiration, Pneumonia
intraarticular = ___physeal
guttate psoriasis after infection w/ ?
triangle filled w/reactive bone (osteosarcoma)
Which? Tip 3-5 cm above the carina
Earliest symptom of malignant melanoma
Anti-Ro (SS-A) assoc w/ ? in newborn babies
loss of intercellular bridges of stratum spinosum
skin tags, aka ?
Most severe SE from steroid withdrawal
hyperplasia/thickening of stratum spinosum
hyperplasia/thickening of stratum corneum
'Rat bite' erosions may be seen when ? are present on xray
Rx: Reverses altered keratinization
Nevus assoc w/ vitiligo and metastatic melanoma
buckling of cortex
localized linear scleroderma
visible under LM with alizarin red staining
Rash with relative central clearing and active peripheral border
TH1 or TH2: eczema
Rx causing celecoxib levels to rise
Enzyme b/t inosinic acid and hypoxanthine
Coral red fluorescence (Woods lamp)
PV or BP: Subepidermal blisters and linear BM IF
wheals - due to release of?
serum urate conc > 6.8 mg/dL
classification system - fx wrt growth plate
sandwich sign (path)
MC neuro sx w/ lupus
Bright red, satellite pustules
Rx: works where cyclosporin fails
proximal muscle weakness and light sensitive rash
Rx: bone marrow and GI toxic, hepatic fibrosis and cirrhosis

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