Science Quiz / Block 8a Tissues

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Can you name the Block 8a Tissues?

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MC location for osteosarcoma
Scarlet fever organism
'Rat bite' erosions may be seen when ? are present on xray
MC joint affected in pseudogout
Usu bacteria in Furuncle
basilar vacuolation/hydropic degeneration of stratum basalis
Central facial erythema/telangiectasia
Rash with relative central clearing and active peripheral border
small fluid filled lesion
Meniscus sign on radiograph
Hyperkeratosis that retains nuclei
Rx: bone marrow and GI toxic, hepatic fibrosis and cirrhosis
MCC of Morbilliform rash
'atypia is full thickness'
Tx for secondary adrenal insufficiency
increased vascular pedicle width
lesion raised less than 1/2cm
Herpes Simplex on finger
reddish-white and shiny lesions on extensor surface, joints of hands
Bowen's dz - ? in situ
intertiginous red streaks in scarlet fever
Mortality in scleroderma assoc w/ ?
false + test for treponema pallidum (and +ANA)
Organism in Acute Paronychia
buckling of cortex
hyperpigmented rete ridges (path)
Antigen assoc w/ most serious dz in polymyositis
ending of selective NSAIDs
MC skin cancer
Hemorrhage, Edema, Aspiration, Pneumonia
wheals - due to release of?
lesion goes through dermis & epidermis
something in elbow pushes ? posteriorly
deposits of monosodium urate (MSU) crystals
lichen planus: white reticulated pattern on top
malignant melanocytic cells; go up into dermis
palpable purpuric lesion after PCN
Which? Tip b/t main PA and bilateral pulm hila
Anti-Ro (SS-A) assoc w/ ? in newborn babies
lesion assoc w/ HHV-8
serum urate conc > 6.8 mg/dL
antidote for acetaminophen OD
midshaft = ___physeal
hemangiomas of infancy are positive for?
Rx causing hyperuricemia
guttate psoriasis after infection w/ ?
LM: intracellular calcium pyrophosphate dihydate (CPPD) crystals
human mab: BLyS-specific inhibitors
hyperkeratosis, hypergranulosis, acanthosis
Acanthosis, parakeratosis, loss of granular layer
flat lesion
Aspirin effect on warfarin
mucuous membrane involvement is hallmark in which skin reaction?
LAH and RBBB most common EKG findings in?
Drug induced acute, generalized skin eruption
Steroids tx autoimmune hemolytic anemia assoc w/ ?
psoriasis usu on which surfaces
MCC: large joint (ie shldr) destructive arthritis
autoimmune dz w/ popped blistering
MC malignant tumor in young adults
triangle filled w/reactive bone (osteosarcoma)
IR tx for liver HCC
MC SE from steroid withdrawal
Angel wing deformity of nails
Which? Tip 3-5 cm above the carina
100% specific for SLE, but only found in 25-30%,
Rx: works where cyclosporin fails
acetic acid derivative that dec arachidonic acid
? predisposes to CPPD deposition diseases
Nevus assoc w/ vitiligo and metastatic melanoma
Rx: FKBP binds/inh mTOR, low nephrotoxicity
Enzyme b/t inosinic acid and hypoxanthine
supracondylar = ___physeal
Firm, violaceous color due to Kasabach-Merritt phenomenon
Anuclear hyperkeratosis
Rx: Bind/cross-links DNA to block synthesis
Primary lesion of acne
Steroid class: dexamethasone/triamcinolone
Uniform, flesh colored papules that koebnerize
Enteric tube with metal, weighted tip
ERCP that has 10% chance of causing ?
Bright red, satellite pustules
papillomatosis and horn pseudocyst
hyperplasia/thickening of stratum spinosum
induced by glucocorticoids to suppress phospholipase A2
bridging, lamellar fibrosis, atypical melanocytes
Umbilicated papules and pox virus
Rate limiting step of purine metabolism
Usu location of Ewing's sarcoma
Superficial cellulitis, Group A Strep, well demarcated, usu face
Dose limiting SE of cyclosporin
most damaging/limiting effect of long term steroids
fluid leakage into peripheral interlobular septa
only NSAID approved for parenteral admin
inhibit platelet aggregation - only rec. use of?
Rx for acute gout: inhibits PMN microtubule assembly
Virus assoc w/ lichen planus
PR like eruption on palms and soles
estogen replacement therapy risk for?
muscle biopsy: inflammation and necrobiotic degeneration
radiography for vascular/aortic injury
zoophilic variant of tinea corporis
MC soft tissue tumor of adulthood
Apple core lesion in colon - MC?
TH1 or TH2: psoriasis
Endocarditis assoc w/ lupus
Inflammatory reaction to yeast Pityrosporum
protein mutation in atopic dermatitis
Candida - labial commissure
Irregular metaphyseal corners assoc w/ ?
Decade that IR was born
'atypia is not full thickness'
Rx class: inh beta-1,3 glucan synthesis
Explosive onset of pruritic SKs - sign of?
PV or BP: Suprabasal acantholytic blister
Facial nerve involvement with Zoster
sv dermal effect assoc w/ inhibition of prostaglandin synth
Deep sulcus sign on radiograph
Corynebacterium minitussimum
only selective NSAID on the market
Type of arthritis in lupus
Syndrome assoc w/ prox coarctation of the aorta
Rx: Raynaud's
MC electrolyte change with Lung SCC
Candida - groin, axilla, inframammary
arborizing vascular network; cellular lipocytes w/ “chicken wire” vessels
migration of embryotic lines during development
Type of necrosis in vasculitis
gold standard for dx of allergic contact dermatitis
MC neuro sx w/ lupus
Pityriasis Rosea starts with
Rx causing celecoxib levels to rise
visible under LM with alizarin red staining
Salmon/white/brown rash on back/chest in summer months
non-purine selective inhibitor of xanthine oxidase
Koebner's phenomenon occur in areas of?
Pruritic, purple polygonal papules
thick 'silvery white scale'
Batwing appearance
Rx for SJS
Most severe SE from steroid withdrawal
When pos, titer useful for monitoring lupus activity
scleroderma limited to skin of fingers and face
MC crystal in BCP deposition disease
Long glucocorticoid duration - low or high 11β-HSD II binding affinity?
Test w/ negative predictive value 95% for lupus
Syndrome assoc w/ capillary malformation in V1
Gold standard test: fungi in skin hair and nails
classification system - fx wrt growth plate
scalp lesion but different part of follicle c/w epidermal incl cyst
Lesion called burrow
brown patch on shldr that grows hair @ puberty
hyperparpathyroid & hypothyroid decrease uric acid ?
ACTH excess
target lesions, classically
skin cond: steroid withdrawal may cause?
Antiphospholipid syndrome - ab against?
exudate filled lesion
premies at risk for which skin condition?
limited scleroderma - spec antibody to ?
Rx: correct acid-base imbalance with ASA OD
Codman triangle, sunburst pattern
leathery skin in bilateral, diffuse, distal areas
Dz: linear nodules along lymphatics
Dx: dec re-utilization of purine bases in the salvage pathways
arterial and venous thromboses, spont abortions, and low platelets
Mult epidermal incl cysts, osteomas, fibromas, lipomas
eczema usu on which surfaces
acanthosis w/ basal hyperpigmentation
Earliest symptom of malignant melanoma
Large deep Staph Aureus abscesses
class: principally salt-retaining activity
fracture of cortex
hyperplasia/thickening of stratum corneum
diffuse scleroderma - spec antibody to ?
localized linear scleroderma
localized thickening and tightness of the skin of fingers or toes
Dogs/cats dont get gout b/c they have ?
autoimmune dz w/ intact bullae
'dew drop on a rose petal'
PV or BP: Subepidermal blisters and linear BM IF
proximal muscle weakness and light sensitive rash
Rx class: squalene epoxidase
Anti-La (SS-B) and Ro also present in ?
papillomatosis, perinuclear halo, prominent keratohyaline
MAb to prevent acute phase rejection
'net like'
Thickness from top of granular layer to bottom of deepest lesion
ephelides, aka ?
XR: periarticular deposits of apatite
skin tags, aka ?
sandwich sign (path)
swelling of liver/brain with ASA
MC form of oral LP
Coral red fluorescence (Woods lamp)
Candida - nail cuticle
loss of intercellular bridges of stratum spinosum
Linear dermatosis, primarily affects children
In PV, autoantibodies are against ?
Syndrome assoc w/ Complex Vascular Malformation
Rx: Reverses altered keratinization
Hypoxemia & etoh tox ? urate reabsorption
“coin shaped” eczema
First joint affected in gout
honey colored crust by kid's mouth
TH1 or TH2: eczema
fludrocortisone is tx for?
lentigines on lips/oral mucosa, abd pain
clefting artifact, myxoid stroma
intraarticular = ___physeal
Erythematous raised patches w/ adherent keratotic scaling and follicular plugging
Tip of PICC at junction of SVC and ?
Rx class: lanosterol demethylase
Rx: block memory B cells and inh lymphocyte proliferation
Hydralazine and minocycline both cause?
internal neurofibroma, cafe-au-lait spots

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