Science Quiz / Block 8a Tissues

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Can you name the Block 8a Tissues?

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leathery skin in bilateral, diffuse, distal areas
'atypia is full thickness'
target lesions, classically
Tip of PICC at junction of SVC and ?
Steroids tx autoimmune hemolytic anemia assoc w/ ?
Deep sulcus sign on radiograph
buckling of cortex
ERCP that has 10% chance of causing ?
Rx class: inh beta-1,3 glucan synthesis
thick 'silvery white scale'
Linear dermatosis, primarily affects children
inhibit platelet aggregation - only rec. use of?
Rx: block memory B cells and inh lymphocyte proliferation
Drug induced acute, generalized skin eruption
protein mutation in atopic dermatitis
induced by glucocorticoids to suppress phospholipase A2
MC location for osteosarcoma
sv dermal effect assoc w/ inhibition of prostaglandin synth
skin tags, aka ?
Syndrome assoc w/ capillary malformation in V1
honey colored crust by kid's mouth
lichen planus: white reticulated pattern on top
arborizing vascular network; cellular lipocytes w/ “chicken wire” vessels
Tx for secondary adrenal insufficiency
visible under LM with alizarin red staining
MC crystal in BCP deposition disease
Rx: works where cyclosporin fails
TH1 or TH2: psoriasis
Type of necrosis in vasculitis
First joint affected in gout
hyperkeratosis, hypergranulosis, acanthosis
Rx causing hyperuricemia
lesion assoc w/ HHV-8
Earliest symptom of malignant melanoma
clefting artifact, myxoid stroma
Usu bacteria in Furuncle
MCC: large joint (ie shldr) destructive arthritis
Anti-La (SS-B) and Ro also present in ?
PR like eruption on palms and soles
Gold standard test: fungi in skin hair and nails
hyperplasia/thickening of stratum spinosum
Dz: linear nodules along lymphatics
Bowen's dz - ? in situ
palpable purpuric lesion after PCN
Anti-Ro (SS-A) assoc w/ ? in newborn babies
sandwich sign (path)
brown patch on shldr that grows hair @ puberty
Herpes Simplex on finger
Pityriasis Rosea starts with
basilar vacuolation/hydropic degeneration of stratum basalis
Mult epidermal incl cysts, osteomas, fibromas, lipomas
Hypoxemia & etoh tox ? urate reabsorption
bridging, lamellar fibrosis, atypical melanocytes
Syndrome assoc w/ prox coarctation of the aorta
papillomatosis, perinuclear halo, prominent keratohyaline
Enzyme b/t inosinic acid and hypoxanthine
MCC of Morbilliform rash
Syndrome assoc w/ Complex Vascular Malformation
gold standard for dx of allergic contact dermatitis
Mortality in scleroderma assoc w/ ?
localized thickening and tightness of the skin of fingers or toes
papillomatosis and horn pseudocyst
Rx causing celecoxib levels to rise
Hemorrhage, Edema, Aspiration, Pneumonia
wheals - due to release of?
Rx class: lanosterol demethylase
Dogs/cats dont get gout b/c they have ?
Thickness from top of granular layer to bottom of deepest lesion
Rx: Raynaud's
Which? Tip b/t main PA and bilateral pulm hila
Test w/ negative predictive value 95% for lupus
lesion raised less than 1/2cm
100% specific for SLE, but only found in 25-30%,
MC neuro sx w/ lupus
supracondylar = ___physeal
TH1 or TH2: eczema
Rx: Reverses altered keratinization
XR: periarticular deposits of apatite
loss of intercellular bridges of stratum spinosum
lesion goes through dermis & epidermis
something in elbow pushes ? posteriorly
Superficial cellulitis, Group A Strep, well demarcated, usu face
Salmon/white/brown rash on back/chest in summer months
PV or BP: Suprabasal acantholytic blister
eczema usu on which surfaces
guttate psoriasis after infection w/ ?
Hydralazine and minocycline both cause?
muscle biopsy: inflammation and necrobiotic degeneration
diffuse scleroderma - spec antibody to ?
internal neurofibroma, cafe-au-lait spots
migration of embryotic lines during development
localized linear scleroderma
Decade that IR was born
MC joint affected in pseudogout
autoimmune dz w/ intact bullae
Koebner's phenomenon occur in areas of?
When pos, titer useful for monitoring lupus activity
Anuclear hyperkeratosis
arterial and venous thromboses, spont abortions, and low platelets
Organism in Acute Paronychia
triangle filled w/reactive bone (osteosarcoma)
Pruritic, purple polygonal papules
Nevus assoc w/ vitiligo and metastatic melanoma
'dew drop on a rose petal'
malignant melanocytic cells; go up into dermis
premies at risk for which skin condition?
ephelides, aka ?
Antigen assoc w/ most serious dz in polymyositis
? predisposes to CPPD deposition diseases
Type of arthritis in lupus
Batwing appearance
exudate filled lesion
Large deep Staph Aureus abscesses
“coin shaped” eczema
ending of selective NSAIDs
Which? Tip 3-5 cm above the carina
flat lesion
Steroid class: dexamethasone/triamcinolone
Candida - nail cuticle
Aspirin effect on warfarin
fluid leakage into peripheral interlobular septa
Codman triangle, sunburst pattern
class: principally salt-retaining activity
human mab: BLyS-specific inhibitors
In PV, autoantibodies are against ?
most damaging/limiting effect of long term steroids
Candida - groin, axilla, inframammary
skin cond: steroid withdrawal may cause?
Erythematous raised patches w/ adherent keratotic scaling and follicular plugging
Primary lesion of acne
MAb to prevent acute phase rejection
fludrocortisone is tx for?
Uniform, flesh colored papules that koebnerize
scalp lesion but different part of follicle c/w epidermal incl cyst
proximal muscle weakness and light sensitive rash
Explosive onset of pruritic SKs - sign of?
hemangiomas of infancy are positive for?
Lesion called burrow
Dx: dec re-utilization of purine bases in the salvage pathways
Irregular metaphyseal corners assoc w/ ?
estogen replacement therapy risk for?
midshaft = ___physeal
MC soft tissue tumor of adulthood
'net like'
Scarlet fever organism
Central facial erythema/telangiectasia
intraarticular = ___physeal
Rx: correct acid-base imbalance with ASA OD
Enteric tube with metal, weighted tip
Rate limiting step of purine metabolism
lentigines on lips/oral mucosa, abd pain
MC SE from steroid withdrawal
acetic acid derivative that dec arachidonic acid
MC skin cancer
intertiginous red streaks in scarlet fever
fracture of cortex
only NSAID approved for parenteral admin
Rx for SJS
acanthosis w/ basal hyperpigmentation
PV or BP: Subepidermal blisters and linear BM IF
reddish-white and shiny lesions on extensor surface, joints of hands
Rx: Bind/cross-links DNA to block synthesis
limited scleroderma - spec antibody to ?
hyperpigmented rete ridges (path)
Inflammatory reaction to yeast Pityrosporum
swelling of liver/brain with ASA
ACTH excess
Acanthosis, parakeratosis, loss of granular layer
Meniscus sign on radiograph
MC malignant tumor in young adults
MC electrolyte change with Lung SCC
false + test for treponema pallidum (and +ANA)
Usu location of Ewing's sarcoma
Bright red, satellite pustules
Hyperkeratosis that retains nuclei
Candida - labial commissure
only selective NSAID on the market
'Rat bite' erosions may be seen when ? are present on xray
non-purine selective inhibitor of xanthine oxidase
hyperparpathyroid & hypothyroid decrease uric acid ?
Firm, violaceous color due to Kasabach-Merritt phenomenon
hyperplasia/thickening of stratum corneum
Antiphospholipid syndrome - ab against?
Rash with relative central clearing and active peripheral border
autoimmune dz w/ popped blistering
Long glucocorticoid duration - low or high 11β-HSD II binding affinity?
mucuous membrane involvement is hallmark in which skin reaction?
serum urate conc > 6.8 mg/dL
LAH and RBBB most common EKG findings in?
Apple core lesion in colon - MC?
MC form of oral LP
antidote for acetaminophen OD
Corynebacterium minitussimum
Most severe SE from steroid withdrawal
classification system - fx wrt growth plate
Rx for acute gout: inhibits PMN microtubule assembly
radiography for vascular/aortic injury
Virus assoc w/ lichen planus
IR tx for liver HCC
Rx: bone marrow and GI toxic, hepatic fibrosis and cirrhosis
LM: intracellular calcium pyrophosphate dihydate (CPPD) crystals
Umbilicated papules and pox virus
'atypia is not full thickness'
Coral red fluorescence (Woods lamp)
Endocarditis assoc w/ lupus
Angel wing deformity of nails
small fluid filled lesion
increased vascular pedicle width
deposits of monosodium urate (MSU) crystals
Dose limiting SE of cyclosporin
psoriasis usu on which surfaces
Rx: FKBP binds/inh mTOR, low nephrotoxicity
Rx class: squalene epoxidase
scleroderma limited to skin of fingers and face
zoophilic variant of tinea corporis
Facial nerve involvement with Zoster

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