Science Quiz / Block 8a GI

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Can you name the Block 8a GI?

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QuestionAnswerNotes
triad of RUQ pain, jaundice, fever in Cholangitis
Rx that reduces portal blood flow
Location: polypoid carcinoma, obstruction rare
hepatitis:ground-glass cytoplasmic change
“ringed esophagus” aka “tracheal-ization” of esophagus
Lack of brush border disaccharidase (MC)
Laxative class: Polyethylene glycol
omega sign on abd xray
unconjugated bilirubin goes to kids' brain
liver dz: pruritis and elevated alk phos
Colonic dilation and toxic megacolon - risk of?
flask like outpouchings along taeniae coli
incomplete relaxation of the ileus and complete lack of contraction
Tumor arising from Interstitial Cells of Cajal
Partial thickness traumatic esophageal tear
Long term tx w/ ? for aplastic anemia has HCC assoc
Liver dz: long-term low dose OCPs
Laxative class: Docusates
Rx c/i with 6-MP due to XO
constipation + cant pass gas
hallmark: surface epithelial damage w/ inc intraepithelial lymphocytes
MC neoplastic polyps
Key Tx for acute pancreatitis
hallmark of pill esophagitis
MCC bacterial enterocolitis in developed countries
Child w/ liver tumor, normal AFP
Impacted gallstone in cystic duct
inherited deficiency w/o cirrhosis - risk of HCC
AD mutation of DNA mismatch repair genes
Measure of distal intestinal function
Anti-CD117 stain
marked reduction, or complete absence of myenteric ganglion cells
Tx: Zenker's diverticula
pt w/ cirrhosis suddenly decompensates
MC inactivated tumor suppressor gene in pancreatic ca
iron deficiency anemia - where is colon cancer?
esophageal webs, iron deficiency anemia, glossitis, and koilonychias
Abd CA w/ germline BRCA mutation
MCC lower GI bleed
MC site for Gastric adenocarcinoma
Dx: trypsin activity not inhibited
Usu location of mesenteric thrombosis due to atherosclerosis
Radiology: double duct sign
pancreatitis & perf ulcer referred pain?
MCC chronic liver test elevation (USA)
Test for hepatocellular carcinoma or germ cell neoplasm
Alarm sx or age > 50, should do?
migratory thrombophlebitis due to procoagulants and platelet
Crohn's dz - inc risk of?
more often with alcohol than NASH
High gastrin, no acid. Dx?
E histolytica resistant to gastric acid due to?
Earliest disease in Crohn's
MCC Small bowel obstruction
MC mets for colon carcinoma
margination, molding, multi-nucleation
charcot's + hypotension & change in mental status
Ulcers in late intestine +diarrhea. Dx?
Poor prognosis in adenocarcinoma w/ production of?
Malformed submucosal and mucosal blood vessels
Crohn's: TH1 or TH2
Hallmark: nuclear hyperchromasia, elongation and stratification
Bacteria - inc risk of colorectal CA
diarrhea type - IBD
Dx: intrinsic malignant obstruction of BD
QuestionAnswerNotes
Initiating event of acute pancreatitis activates ?
Whipple's triad (hypoglycemia etc)
MC clinically significant deficiency in alpha-1-antitrypsin
Key pattern for carcinoid tumor
Cellular swelling with damage
MC place for esophageal web
Concentric peri-bile duct fibrosis
lymphoma exclusively in young males
diarrhea - high volume, persists w/ fasting
Narrowing of lower esophagus causing difficulty swallowing
colicky, midabd pain, vomiting, obstipation
Angiodysplasia is ? % of major lower GI bleed
Test for B12 Absorption
diarrhea - large volume, dec w/ fasting
Inflammatory cell assoc w/ acute viral hepatitis
Maintenance therapy for Crohn's dz
colorectal CA - highest incidence in?
Necrosis caused by alkaline injury?
persistence of prox vitelline duct
Diffuse foamy appearance of swollen hepatocytes
Crohn's mutation on chromosome 16
Virus assoc w/ Natalizumab
Urea Beath Test for?
Dev encephalopathy w/i 6 wks of onset of acute hepatitis
Dz producing agent in celiac disease
MC location for polyp
impairment of bile flow and failure to secrete bile
RLQ Dx: neutrophils in muscularis propria
MCC Upper GI bleed?
H/o vomiting, then emesis turned bloody
Achalasia - inc risk of?
Worst necrosis in chronic hepatitis
Necrosis caused by acid injury?
Prophylactic abx for varices?
UC or CD: inc risk with tobacco
Most sensitive imaging for early pancreatitis
IBS MC in which ethnic group?
AR, HFE gene on chromsome 6
diarrhea type - sorbitol ingestion
pitch of bowel sounds with SBO or ileus
macrophages crowd intestine + diarrhea, weight loss and malabsorption
MC genetic alteration in pancreatic CA
Test - Identifies lesions in distal 60cm
Medium Chain Triglycerides transported via?
6-MP metabolite most effective in controlling inflammation
test for Wilson's dz (decreased)
IBS regional enteritis (skip), transmural
MC GI malignancy
Liver dz, women 20-40
obstructive or parenchymal: transaminases >400 U/L
Cure for UC
MC benign tumor
diarrhea, sm volume, guaiac pos
ALT or AST - more elevated in ETOH
toxic product of Aspergillus flavus
UGT1A1 promoter mutation
histiologic hallmark of Crohn's dz
Liver dz w/ inc NH3 and inc tendon reflexes
ventral bud rotates in front of duodenum
Invasion more in which adenomas?
Candida species w/ inc potential for tissue invasion
Inheritance of Familial Adenomatous Polyposis
pt w/ UC and ? dz need immediate CA check
pebble like stool
flask shaped ulcer and liver abscess
QuestionAnswerNotes
bowel sounds with peritonitis
diarrhea type - disaccharide deficiency
IPMN: greater risk of associated carcinoma in?
Low ? = severity of hepatocellular dysfunction
Vit K absorption is dependent on ?
IBS tx if primary sx is constipation
LAE patients are especially vulnerable to?
Tx: Crigler-Najjar Type II
jaundice w/o + urine bilirubin is due to?
MCC portal hypertension
Failure of fusion of dorsal and ventral ducts
Tx Entamoeba histolytica
Laxative class: Bisacodyl and Senna
Prostaglandin analogues for ulcers
pancreatic neoplasm in young women
sudden pain out of proportion to exam + heart dz
Complete twisting of a loop of bowel
Rx: acute variceal bleeding
Dx: trypsinogen and trypsin not inactivated
diarrhea type - enterotoxin
C/I to fundoplication
MC tumor of appendix
Fibrosis that compresses the ureters
% pt w/ distant mets at dx of pancreatic CA
ALT or AST - mainly in liver
remove GB, CBD, part of duodenum, HOP
diarrhea type - ZE
only human protozoa that lives in the duodenum
MC stomach malignancy
Peritonitis - MC bacteria (besides E coli)
MC CA assoc w/ celiac disease
Tx for Wilson's dz
MC mesenchymal tumor of abd
UC or CD: PSC, p gangrenosum
most widely used Rx for UC
UGT1A1 coding mutation, conjugation absent
CD4 T cells against parietal cell components
MC abx causing C. difficile overgrowth
UC or CD: ankylosing spondylitis, e nodosum
Test to monitor if enough fluids for pancreatitis
Measure of proximal intestinal function
Rx: competitively inhibits uptake transport protein (bilirubin)
Tx for Aortoenteric fistulas?
Full-thickness outpouchings of the esophageal wall, usu cervical
high alk phos with normal GGT - source?
diarrhea - sm volume, dec w/ fasting
upper GI bleed proximal to?
GI hamartomas w/ hyperpigmented lips, hands, etc
child w/ parasite in appendix - MC?
Location: annular with 'napkin-ring' constrictions and luminal obstruction
MC location for pancreatic carcinoma
Rx: prevent variceal re-bleeding
Specific test of hepatobiliary dysfunction
Serum Albumin - Ascitic Albumin >1.1
MC type of esophageal CA
Dx: 'punched out' aphthae
orderly peristaltic sequence w/ high amplitude on manometry
antibodies + in 95% primary biliary cirrhosis
straight line of contraction on manometry
pro drug metabolized to 6-MP
Given to get rid of ammonia in the GI tract
Sessile or pedunculated - highest risk of CA?
Test for ability to detoxify
IBS limited to colon/rectum, mucosa/submucosa
FAP + osseous and soft tissue tumors

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