Science Quiz / Block 8a GI

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Can you name the Block 8a GI?

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QuestionAnswerNotes
LAE patients are especially vulnerable to?
liver dz: pruritis and elevated alk phos
MC stomach malignancy
Tx for Wilson's dz
Rx: competitively inhibits uptake transport protein (bilirubin)
FAP + osseous and soft tissue tumors
Test - Identifies lesions in distal 60cm
pancreatic neoplasm in young women
pro drug metabolized to 6-MP
UC or CD: PSC, p gangrenosum
Lack of brush border disaccharidase (MC)
Virus assoc w/ Natalizumab
orderly peristaltic sequence w/ high amplitude on manometry
Invasion more in which adenomas?
iron deficiency anemia - where is colon cancer?
hallmark: surface epithelial damage w/ inc intraepithelial lymphocytes
Rx: prevent variceal re-bleeding
toxic product of Aspergillus flavus
Tx: Crigler-Najjar Type II
Usu location of mesenteric thrombosis due to atherosclerosis
Complete twisting of a loop of bowel
Dx: trypsinogen and trypsin not inactivated
IBS tx if primary sx is constipation
Liver dz: long-term low dose OCPs
Poor prognosis in adenocarcinoma w/ production of?
Initiating event of acute pancreatitis activates ?
Rx: acute variceal bleeding
UGT1A1 promoter mutation
diarrhea type - IBD
Crohn's dz - inc risk of?
% pt w/ distant mets at dx of pancreatic CA
margination, molding, multi-nucleation
Low ? = severity of hepatocellular dysfunction
Hallmark: nuclear hyperchromasia, elongation and stratification
AD mutation of DNA mismatch repair genes
Laxative class: Docusates
more often with alcohol than NASH
Dx: trypsin activity not inhibited
UC or CD: ankylosing spondylitis, e nodosum
Test to monitor if enough fluids for pancreatitis
only human protozoa that lives in the duodenum
Dz producing agent in celiac disease
MC mesenchymal tumor of abd
GI hamartomas w/ hyperpigmented lips, hands, etc
sudden pain out of proportion to exam + heart dz
pebble like stool
child w/ parasite in appendix - MC?
pancreatitis & perf ulcer referred pain?
MC benign tumor
MC type of esophageal CA
Full-thickness outpouchings of the esophageal wall, usu cervical
MCC bacterial enterocolitis in developed countries
Test for hepatocellular carcinoma or germ cell neoplasm
MCC Upper GI bleed?
Laxative class: Bisacodyl and Senna
impairment of bile flow and failure to secrete bile
IBS regional enteritis (skip), transmural
Long term tx w/ ? for aplastic anemia has HCC assoc
Measure of proximal intestinal function
Impacted gallstone in cystic duct
lymphoma exclusively in young males
Location: annular with 'napkin-ring' constrictions and luminal obstruction
Malformed submucosal and mucosal blood vessels
antibodies + in 95% primary biliary cirrhosis
diarrhea - large volume, dec w/ fasting
QuestionAnswerNotes
migratory thrombophlebitis due to procoagulants and platelet
colicky, midabd pain, vomiting, obstipation
6-MP metabolite most effective in controlling inflammation
Cure for UC
Child w/ liver tumor, normal AFP
colorectal CA - highest incidence in?
diarrhea, sm volume, guaiac pos
MC neoplastic polyps
diarrhea type - ZE
ventral bud rotates in front of duodenum
most widely used Rx for UC
MCC chronic liver test elevation (USA)
AR, HFE gene on chromsome 6
Dev encephalopathy w/i 6 wks of onset of acute hepatitis
upper GI bleed proximal to?
MC GI malignancy
MCC Small bowel obstruction
constipation + cant pass gas
Inflammatory cell assoc w/ acute viral hepatitis
omega sign on abd xray
MC place for esophageal web
Cellular swelling with damage
Key Tx for acute pancreatitis
H/o vomiting, then emesis turned bloody
flask shaped ulcer and liver abscess
Crohn's mutation on chromosome 16
marked reduction, or complete absence of myenteric ganglion cells
flask like outpouchings along taeniae coli
MC abx causing C. difficile overgrowth
diarrhea type - disaccharide deficiency
Most sensitive imaging for early pancreatitis
Necrosis caused by acid injury?
Rx c/i with 6-MP due to XO
Given to get rid of ammonia in the GI tract
Crohn's: TH1 or TH2
“ringed esophagus” aka “tracheal-ization” of esophagus
Urea Beath Test for?
Test for B12 Absorption
Tx: Zenker's diverticula
charcot's + hypotension & change in mental status
Diffuse foamy appearance of swollen hepatocytes
Sessile or pedunculated - highest risk of CA?
Earliest disease in Crohn's
Necrosis caused by alkaline injury?
MCC lower GI bleed
Tx Entamoeba histolytica
incomplete relaxation of the ileus and complete lack of contraction
Achalasia - inc risk of?
Angiodysplasia is ? % of major lower GI bleed
Prostaglandin analogues for ulcers
Narrowing of lower esophagus causing difficulty swallowing
Location: polypoid carcinoma, obstruction rare
IBS MC in which ethnic group?
Liver dz w/ inc NH3 and inc tendon reflexes
Prophylactic abx for varices?
Failure of fusion of dorsal and ventral ducts
Laxative class: Polyethylene glycol
high alk phos with normal GGT - source?
unconjugated bilirubin goes to kids' brain
Concentric peri-bile duct fibrosis
MC inactivated tumor suppressor gene in pancreatic ca
Serum Albumin - Ascitic Albumin >1.1
pitch of bowel sounds with SBO or ileus
diarrhea type - sorbitol ingestion
jaundice w/o + urine bilirubin is due to?
QuestionAnswerNotes
macrophages crowd intestine + diarrhea, weight loss and malabsorption
Peritonitis - MC bacteria (besides E coli)
Radiology: double duct sign
MCC portal hypertension
High gastrin, no acid. Dx?
Inheritance of Familial Adenomatous Polyposis
MC tumor of appendix
diarrhea - high volume, persists w/ fasting
test for Wilson's dz (decreased)
Ulcers in late intestine +diarrhea. Dx?
C/I to fundoplication
hallmark of pill esophagitis
ALT or AST - mainly in liver
Candida species w/ inc potential for tissue invasion
Dx: 'punched out' aphthae
Whipple's triad (hypoglycemia etc)
diarrhea type - enterotoxin
inherited deficiency w/o cirrhosis - risk of HCC
RLQ Dx: neutrophils in muscularis propria
MC location for pancreatic carcinoma
MC clinically significant deficiency in alpha-1-antitrypsin
MC site for Gastric adenocarcinoma
Specific test of hepatobiliary dysfunction
Medium Chain Triglycerides transported via?
Alarm sx or age > 50, should do?
Tx for Aortoenteric fistulas?
Measure of distal intestinal function
UC or CD: inc risk with tobacco
straight line of contraction on manometry
Vit K absorption is dependent on ?
hepatitis:ground-glass cytoplasmic change
IPMN: greater risk of associated carcinoma in?
Fibrosis that compresses the ureters
ALT or AST - more elevated in ETOH
MC mets for colon carcinoma
pt w/ UC and ? dz need immediate CA check
Abd CA w/ germline BRCA mutation
Key pattern for carcinoid tumor
MC location for polyp
Anti-CD117 stain
bowel sounds with peritonitis
Partial thickness traumatic esophageal tear
Tumor arising from Interstitial Cells of Cajal
MC CA assoc w/ celiac disease
IBS limited to colon/rectum, mucosa/submucosa
triad of RUQ pain, jaundice, fever in Cholangitis
Dx: intrinsic malignant obstruction of BD
MC genetic alteration in pancreatic CA
Bacteria - inc risk of colorectal CA
diarrhea - sm volume, dec w/ fasting
Test for ability to detoxify
Maintenance therapy for Crohn's dz
obstructive or parenchymal: transaminases >400 U/L
UGT1A1 coding mutation, conjugation absent
Liver dz, women 20-40
Worst necrosis in chronic hepatitis
Rx that reduces portal blood flow
E histolytica resistant to gastric acid due to?
histiologic hallmark of Crohn's dz
esophageal webs, iron deficiency anemia, glossitis, and koilonychias
pt w/ cirrhosis suddenly decompensates
CD4 T cells against parietal cell components
Colonic dilation and toxic megacolon - risk of?
persistence of prox vitelline duct
remove GB, CBD, part of duodenum, HOP

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Created Oct 21, 2012ReportFavoriteNominate
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