Science Quiz / Block 8a GI

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Can you name the Block 8a GI?

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UC or CD: ankylosing spondylitis, e nodosum
Rx that reduces portal blood flow
Inflammatory cell assoc w/ acute viral hepatitis
Liver dz, women 20-40
Dx: trypsin activity not inhibited
Tumor arising from Interstitial Cells of Cajal
Colonic dilation and toxic megacolon - risk of?
IPMN: greater risk of associated carcinoma in?
MC genetic alteration in pancreatic CA
Rx: acute variceal bleeding
MC location for pancreatic carcinoma
Rx: competitively inhibits uptake transport protein (bilirubin)
colicky, midabd pain, vomiting, obstipation
CD4 T cells against parietal cell components
MC clinically significant deficiency in alpha-1-antitrypsin
child w/ parasite in appendix - MC?
Long term tx w/ ? for aplastic anemia has HCC assoc
MC inactivated tumor suppressor gene in pancreatic ca
Test to monitor if enough fluids for pancreatitis
UGT1A1 coding mutation, conjugation absent
Crohn's: TH1 or TH2
Test for B12 Absorption
UC or CD: inc risk with tobacco
Laxative class: Docusates
more often with alcohol than NASH
Measure of proximal intestinal function
bowel sounds with peritonitis
Candida species w/ inc potential for tissue invasion
test for Wilson's dz (decreased)
pro drug metabolized to 6-MP
Dev encephalopathy w/i 6 wks of onset of acute hepatitis
hallmark of pill esophagitis
Full-thickness outpouchings of the esophageal wall, usu cervical
Fibrosis that compresses the ureters
Crohn's dz - inc risk of?
Tx for Wilson's dz
MC GI malignancy
antibodies + in 95% primary biliary cirrhosis
iron deficiency anemia - where is colon cancer?
MC neoplastic polyps
Location: polypoid carcinoma, obstruction rare
Dx: trypsinogen and trypsin not inactivated
UC or CD: PSC, p gangrenosum
diarrhea type - ZE
MC CA assoc w/ celiac disease
charcot's + hypotension & change in mental status
diarrhea - large volume, dec w/ fasting
Earliest disease in Crohn's
high alk phos with normal GGT - source?
Test for hepatocellular carcinoma or germ cell neoplasm
Vit K absorption is dependent on ?
hallmark: surface epithelial damage w/ inc intraepithelial lymphocytes
AD mutation of DNA mismatch repair genes
Partial thickness traumatic esophageal tear
liver dz: pruritis and elevated alk phos
esophageal webs, iron deficiency anemia, glossitis, and koilonychias
Prostaglandin analogues for ulcers
Whipple's triad (hypoglycemia etc)
diarrhea, sm volume, guaiac pos
% pt w/ distant mets at dx of pancreatic CA
remove GB, CBD, part of duodenum, HOP
persistence of prox vitelline duct
Impacted gallstone in cystic duct
LAE patients are especially vulnerable to?
Abd CA w/ germline BRCA mutation
Dz producing agent in celiac disease
Necrosis caused by acid injury?
Tx: Zenker's diverticula
Tx Entamoeba histolytica
Initiating event of acute pancreatitis activates ?
MC site for Gastric adenocarcinoma
MCC chronic liver test elevation (USA)
Medium Chain Triglycerides transported via?
Measure of distal intestinal function
Ulcers in late intestine +diarrhea. Dx?
IBS limited to colon/rectum, mucosa/submucosa
Sessile or pedunculated - highest risk of CA?
Test for ability to detoxify
Urea Beath Test for?
Radiology: double duct sign
Rx: prevent variceal re-bleeding
Complete twisting of a loop of bowel
macrophages crowd intestine + diarrhea, weight loss and malabsorption
marked reduction, or complete absence of myenteric ganglion cells
diarrhea type - disaccharide deficiency
colorectal CA - highest incidence in?
MCC Small bowel obstruction
lymphoma exclusively in young males
IBS tx if primary sx is constipation
Child w/ liver tumor, normal AFP
Tx: Crigler-Najjar Type II
FAP + osseous and soft tissue tumors
“ringed esophagus” aka “tracheal-ization” of esophagus
Malformed submucosal and mucosal blood vessels
Liver dz: long-term low dose OCPs
MCC bacterial enterocolitis in developed countries
toxic product of Aspergillus flavus
Given to get rid of ammonia in the GI tract
GI hamartomas w/ hyperpigmented lips, hands, etc
Maintenance therapy for Crohn's dz
IBS MC in which ethnic group?
diarrhea - sm volume, dec w/ fasting
obstructive or parenchymal: transaminases >400 U/L
sudden pain out of proportion to exam + heart dz
MC benign tumor
ALT or AST - more elevated in ETOH
inherited deficiency w/o cirrhosis - risk of HCC
incomplete relaxation of the ileus and complete lack of contraction
Rx c/i with 6-MP due to XO
ventral bud rotates in front of duodenum
margination, molding, multi-nucleation
E histolytica resistant to gastric acid due to?
Worst necrosis in chronic hepatitis
flask shaped ulcer and liver abscess
only human protozoa that lives in the duodenum
Alarm sx or age > 50, should do?
C/I to fundoplication
Invasion more in which adenomas?
Laxative class: Bisacodyl and Senna
pancreatitis & perf ulcer referred pain?
Location: annular with 'napkin-ring' constrictions and luminal obstruction
UGT1A1 promoter mutation
Lack of brush border disaccharidase (MC)
impairment of bile flow and failure to secrete bile
Diffuse foamy appearance of swollen hepatocytes
Narrowing of lower esophagus causing difficulty swallowing
diarrhea type - enterotoxin
MC mesenchymal tumor of abd
MCC lower GI bleed
diarrhea type - sorbitol ingestion
AR, HFE gene on chromsome 6
MCC Upper GI bleed?
Necrosis caused by alkaline injury?
MC tumor of appendix
Key pattern for carcinoid tumor
Bacteria - inc risk of colorectal CA
Serum Albumin - Ascitic Albumin >1.1
Virus assoc w/ Natalizumab
most widely used Rx for UC
diarrhea - high volume, persists w/ fasting
straight line of contraction on manometry
jaundice w/o + urine bilirubin is due to?
Prophylactic abx for varices?
upper GI bleed proximal to?
migratory thrombophlebitis due to procoagulants and platelet
MC abx causing C. difficile overgrowth
unconjugated bilirubin goes to kids' brain
Peritonitis - MC bacteria (besides E coli)
H/o vomiting, then emesis turned bloody
histiologic hallmark of Crohn's dz
Achalasia - inc risk of?
Concentric peri-bile duct fibrosis
Liver dz w/ inc NH3 and inc tendon reflexes
pitch of bowel sounds with SBO or ileus
RLQ Dx: neutrophils in muscularis propria
High gastrin, no acid. Dx?
Crohn's mutation on chromosome 16
orderly peristaltic sequence w/ high amplitude on manometry
pebble like stool
MC place for esophageal web
diarrhea type - IBD
Anti-CD117 stain
constipation + cant pass gas
Usu location of mesenteric thrombosis due to atherosclerosis
hepatitis:ground-glass cytoplasmic change
ALT or AST - mainly in liver
Low ? = severity of hepatocellular dysfunction
pt w/ cirrhosis suddenly decompensates
pancreatic neoplasm in young women
Laxative class: Polyethylene glycol
pt w/ UC and ? dz need immediate CA check
Specific test of hepatobiliary dysfunction
MC type of esophageal CA
Dx: 'punched out' aphthae
MC stomach malignancy
Inheritance of Familial Adenomatous Polyposis
triad of RUQ pain, jaundice, fever in Cholangitis
flask like outpouchings along taeniae coli
6-MP metabolite most effective in controlling inflammation
MCC portal hypertension
Cellular swelling with damage
Failure of fusion of dorsal and ventral ducts
Poor prognosis in adenocarcinoma w/ production of?
MC location for polyp
Test - Identifies lesions in distal 60cm
Cure for UC
Dx: intrinsic malignant obstruction of BD
Key Tx for acute pancreatitis
IBS regional enteritis (skip), transmural
Angiodysplasia is ? % of major lower GI bleed
Most sensitive imaging for early pancreatitis
omega sign on abd xray
Tx for Aortoenteric fistulas?
Hallmark: nuclear hyperchromasia, elongation and stratification
MC mets for colon carcinoma

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