Science Quiz / Block 8a GI

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Can you name the Block 8a GI?

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QuestionAnswerNotes
pitch of bowel sounds with SBO or ileus
Laxative class: Docusates
Malformed submucosal and mucosal blood vessels
MC CA assoc w/ celiac disease
Sessile or pedunculated - highest risk of CA?
diarrhea, sm volume, guaiac pos
iron deficiency anemia - where is colon cancer?
IBS tx if primary sx is constipation
straight line of contraction on manometry
Test for hepatocellular carcinoma or germ cell neoplasm
Location: annular with 'napkin-ring' constrictions and luminal obstruction
ventral bud rotates in front of duodenum
inherited deficiency w/o cirrhosis - risk of HCC
Dz producing agent in celiac disease
liver dz: pruritis and elevated alk phos
marked reduction, or complete absence of myenteric ganglion cells
IPMN: greater risk of associated carcinoma in?
MC abx causing C. difficile overgrowth
Initiating event of acute pancreatitis activates ?
Narrowing of lower esophagus causing difficulty swallowing
MCC portal hypertension
MC clinically significant deficiency in alpha-1-antitrypsin
MC place for esophageal web
diarrhea type - disaccharide deficiency
incomplete relaxation of the ileus and complete lack of contraction
Virus assoc w/ Natalizumab
Most sensitive imaging for early pancreatitis
charcot's + hypotension & change in mental status
GI hamartomas w/ hyperpigmented lips, hands, etc
Radiology: double duct sign
High gastrin, no acid. Dx?
Poor prognosis in adenocarcinoma w/ production of?
Lack of brush border disaccharidase (MC)
Dx: trypsinogen and trypsin not inactivated
MC mets for colon carcinoma
macrophages crowd intestine + diarrhea, weight loss and malabsorption
pt w/ cirrhosis suddenly decompensates
triad of RUQ pain, jaundice, fever in Cholangitis
diarrhea type - enterotoxin
Dx: 'punched out' aphthae
Long term tx w/ ? for aplastic anemia has HCC assoc
histiologic hallmark of Crohn's dz
jaundice w/o + urine bilirubin is due to?
high alk phos with normal GGT - source?
Rx c/i with 6-MP due to XO
Peritonitis - MC bacteria (besides E coli)
Partial thickness traumatic esophageal tear
hallmark of pill esophagitis
lymphoma exclusively in young males
colorectal CA - highest incidence in?
toxic product of Aspergillus flavus
Crohn's mutation on chromosome 16
Crohn's: TH1 or TH2
Measure of proximal intestinal function
Test - Identifies lesions in distal 60cm
Complete twisting of a loop of bowel
hallmark: surface epithelial damage w/ inc intraepithelial lymphocytes
Dx: intrinsic malignant obstruction of BD
test for Wilson's dz (decreased)
Medium Chain Triglycerides transported via?
Impacted gallstone in cystic duct
ALT or AST - more elevated in ETOH
Failure of fusion of dorsal and ventral ducts
Rx: prevent variceal re-bleeding
CD4 T cells against parietal cell components
QuestionAnswerNotes
Rx that reduces portal blood flow
Location: polypoid carcinoma, obstruction rare
child w/ parasite in appendix - MC?
Child w/ liver tumor, normal AFP
Laxative class: Bisacodyl and Senna
Rx: acute variceal bleeding
Key pattern for carcinoid tumor
UC or CD: inc risk with tobacco
LAE patients are especially vulnerable to?
MC benign tumor
Crohn's dz - inc risk of?
Invasion more in which adenomas?
Test to monitor if enough fluids for pancreatitis
Tx: Crigler-Najjar Type II
Liver dz, women 20-40
Serum Albumin - Ascitic Albumin >1.1
MC location for pancreatic carcinoma
Vit K absorption is dependent on ?
UGT1A1 coding mutation, conjugation absent
Colonic dilation and toxic megacolon - risk of?
IBS limited to colon/rectum, mucosa/submucosa
Candida species w/ inc potential for tissue invasion
Achalasia - inc risk of?
Rx: competitively inhibits uptake transport protein (bilirubin)
“ringed esophagus” aka “tracheal-ization” of esophagus
diarrhea type - sorbitol ingestion
migratory thrombophlebitis due to procoagulants and platelet
esophageal webs, iron deficiency anemia, glossitis, and koilonychias
persistence of prox vitelline duct
pancreatic neoplasm in young women
MCC Small bowel obstruction
Fibrosis that compresses the ureters
MCC lower GI bleed
C/I to fundoplication
MC tumor of appendix
H/o vomiting, then emesis turned bloody
obstructive or parenchymal: transaminases >400 U/L
diarrhea type - IBD
E histolytica resistant to gastric acid due to?
UC or CD: PSC, p gangrenosum
Full-thickness outpouchings of the esophageal wall, usu cervical
colicky, midabd pain, vomiting, obstipation
IBS regional enteritis (skip), transmural
AR, HFE gene on chromsome 6
pro drug metabolized to 6-MP
Test for ability to detoxify
Key Tx for acute pancreatitis
MC genetic alteration in pancreatic CA
diarrhea - sm volume, dec w/ fasting
more often with alcohol than NASH
diarrhea - high volume, persists w/ fasting
Cellular swelling with damage
MC type of esophageal CA
pancreatitis & perf ulcer referred pain?
diarrhea - large volume, dec w/ fasting
AD mutation of DNA mismatch repair genes
Tx for Aortoenteric fistulas?
Alarm sx or age > 50, should do?
Usu location of mesenteric thrombosis due to atherosclerosis
MC stomach malignancy
Tx Entamoeba histolytica
only human protozoa that lives in the duodenum
flask shaped ulcer and liver abscess
impairment of bile flow and failure to secrete bile
FAP + osseous and soft tissue tumors
QuestionAnswerNotes
MC GI malignancy
pt w/ UC and ? dz need immediate CA check
Dev encephalopathy w/i 6 wks of onset of acute hepatitis
Abd CA w/ germline BRCA mutation
Tx: Zenker's diverticula
UC or CD: ankylosing spondylitis, e nodosum
Liver dz: long-term low dose OCPs
Necrosis caused by acid injury?
MCC chronic liver test elevation (USA)
Inflammatory cell assoc w/ acute viral hepatitis
bowel sounds with peritonitis
unconjugated bilirubin goes to kids' brain
Whipple's triad (hypoglycemia etc)
MC site for Gastric adenocarcinoma
upper GI bleed proximal to?
sudden pain out of proportion to exam + heart dz
constipation + cant pass gas
Cure for UC
Tumor arising from Interstitial Cells of Cajal
hepatitis:ground-glass cytoplasmic change
Test for B12 Absorption
% pt w/ distant mets at dx of pancreatic CA
Concentric peri-bile duct fibrosis
Diffuse foamy appearance of swollen hepatocytes
margination, molding, multi-nucleation
RLQ Dx: neutrophils in muscularis propria
flask like outpouchings along taeniae coli
MC neoplastic polyps
UGT1A1 promoter mutation
Angiodysplasia is ? % of major lower GI bleed
orderly peristaltic sequence w/ high amplitude on manometry
6-MP metabolite most effective in controlling inflammation
Liver dz w/ inc NH3 and inc tendon reflexes
Low ? = severity of hepatocellular dysfunction
Urea Beath Test for?
MC inactivated tumor suppressor gene in pancreatic ca
Earliest disease in Crohn's
Tx for Wilson's dz
most widely used Rx for UC
Anti-CD117 stain
Worst necrosis in chronic hepatitis
Prophylactic abx for varices?
Measure of distal intestinal function
Hallmark: nuclear hyperchromasia, elongation and stratification
ALT or AST - mainly in liver
omega sign on abd xray
MCC Upper GI bleed?
MC mesenchymal tumor of abd
Inheritance of Familial Adenomatous Polyposis
Specific test of hepatobiliary dysfunction
remove GB, CBD, part of duodenum, HOP
pebble like stool
Laxative class: Polyethylene glycol
MCC bacterial enterocolitis in developed countries
IBS MC in which ethnic group?
diarrhea type - ZE
Dx: trypsin activity not inhibited
Ulcers in late intestine +diarrhea. Dx?
Given to get rid of ammonia in the GI tract
Necrosis caused by alkaline injury?
antibodies + in 95% primary biliary cirrhosis
Prostaglandin analogues for ulcers
Maintenance therapy for Crohn's dz
Bacteria - inc risk of colorectal CA
MC location for polyp

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