Science Quiz / Block 8a GI

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Can you name the Block 8a GI?

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QuestionAnswerNotes
LAE patients are especially vulnerable to?
IBS limited to colon/rectum, mucosa/submucosa
iron deficiency anemia - where is colon cancer?
child w/ parasite in appendix - MC?
Location: polypoid carcinoma, obstruction rare
constipation + cant pass gas
pebble like stool
ALT or AST - mainly in liver
UC or CD: ankylosing spondylitis, e nodosum
high alk phos with normal GGT - source?
Laxative class: Docusates
IBS tx if primary sx is constipation
MC neoplastic polyps
Most sensitive imaging for early pancreatitis
diarrhea type - enterotoxin
Sessile or pedunculated - highest risk of CA?
Necrosis caused by acid injury?
Crohn's dz - inc risk of?
migratory thrombophlebitis due to procoagulants and platelet
margination, molding, multi-nucleation
MC inactivated tumor suppressor gene in pancreatic ca
“ringed esophagus” aka “tracheal-ization” of esophagus
IBS MC in which ethnic group?
Liver dz, women 20-40
Tx for Wilson's dz
IPMN: greater risk of associated carcinoma in?
hepatitis:ground-glass cytoplasmic change
Full-thickness outpouchings of the esophageal wall, usu cervical
6-MP metabolite most effective in controlling inflammation
Test to monitor if enough fluids for pancreatitis
MC mets for colon carcinoma
Abd CA w/ germline BRCA mutation
Narrowing of lower esophagus causing difficulty swallowing
Bacteria - inc risk of colorectal CA
antibodies + in 95% primary biliary cirrhosis
bowel sounds with peritonitis
marked reduction, or complete absence of myenteric ganglion cells
Cellular swelling with damage
RLQ Dx: neutrophils in muscularis propria
UC or CD: PSC, p gangrenosum
High gastrin, no acid. Dx?
pro drug metabolized to 6-MP
UGT1A1 coding mutation, conjugation absent
hallmark of pill esophagitis
diarrhea - sm volume, dec w/ fasting
Prostaglandin analogues for ulcers
Tx: Crigler-Najjar Type II
Inflammatory cell assoc w/ acute viral hepatitis
Whipple's triad (hypoglycemia etc)
FAP + osseous and soft tissue tumors
MC CA assoc w/ celiac disease
GI hamartomas w/ hyperpigmented lips, hands, etc
straight line of contraction on manometry
upper GI bleed proximal to?
Hallmark: nuclear hyperchromasia, elongation and stratification
Initiating event of acute pancreatitis activates ?
triad of RUQ pain, jaundice, fever in Cholangitis
pancreatic neoplasm in young women
diarrhea type - IBD
incomplete relaxation of the ileus and complete lack of contraction
diarrhea - high volume, persists w/ fasting
C/I to fundoplication
MC tumor of appendix
Poor prognosis in adenocarcinoma w/ production of?
Test for B12 Absorption
QuestionAnswerNotes
Urea Beath Test for?
Test for ability to detoxify
Virus assoc w/ Natalizumab
Angiodysplasia is ? % of major lower GI bleed
Crohn's mutation on chromosome 16
MC location for polyp
MCC portal hypertension
flask like outpouchings along taeniae coli
diarrhea type - disaccharide deficiency
orderly peristaltic sequence w/ high amplitude on manometry
Worst necrosis in chronic hepatitis
jaundice w/o + urine bilirubin is due to?
Dx: 'punched out' aphthae
Dev encephalopathy w/i 6 wks of onset of acute hepatitis
ventral bud rotates in front of duodenum
AD mutation of DNA mismatch repair genes
pt w/ cirrhosis suddenly decompensates
UGT1A1 promoter mutation
MC site for Gastric adenocarcinoma
Dz producing agent in celiac disease
Candida species w/ inc potential for tissue invasion
Rx: prevent variceal re-bleeding
histiologic hallmark of Crohn's dz
Long term tx w/ ? for aplastic anemia has HCC assoc
Specific test of hepatobiliary dysfunction
MCC bacterial enterocolitis in developed countries
pitch of bowel sounds with SBO or ileus
E histolytica resistant to gastric acid due to?
ALT or AST - more elevated in ETOH
MCC lower GI bleed
Partial thickness traumatic esophageal tear
CD4 T cells against parietal cell components
Prophylactic abx for varices?
Diffuse foamy appearance of swollen hepatocytes
colicky, midabd pain, vomiting, obstipation
Malformed submucosal and mucosal blood vessels
Maintenance therapy for Crohn's dz
MC stomach malignancy
flask shaped ulcer and liver abscess
MC clinically significant deficiency in alpha-1-antitrypsin
sudden pain out of proportion to exam + heart dz
MCC Upper GI bleed?
Liver dz: long-term low dose OCPs
toxic product of Aspergillus flavus
Achalasia - inc risk of?
Failure of fusion of dorsal and ventral ducts
Tx: Zenker's diverticula
Fibrosis that compresses the ureters
Ulcers in late intestine +diarrhea. Dx?
obstructive or parenchymal: transaminases >400 U/L
IBS regional enteritis (skip), transmural
MC GI malignancy
diarrhea type - ZE
persistence of prox vitelline duct
Child w/ liver tumor, normal AFP
Key pattern for carcinoid tumor
Measure of proximal intestinal function
unconjugated bilirubin goes to kids' brain
Earliest disease in Crohn's
Cure for UC
Anti-CD117 stain
impairment of bile flow and failure to secrete bile
diarrhea - large volume, dec w/ fasting
pt w/ UC and ? dz need immediate CA check
Inheritance of Familial Adenomatous Polyposis
QuestionAnswerNotes
Radiology: double duct sign
Rx c/i with 6-MP due to XO
Low ? = severity of hepatocellular dysfunction
% pt w/ distant mets at dx of pancreatic CA
Usu location of mesenteric thrombosis due to atherosclerosis
Lack of brush border disaccharidase (MC)
UC or CD: inc risk with tobacco
Necrosis caused by alkaline injury?
Rx: acute variceal bleeding
Crohn's: TH1 or TH2
Tx for Aortoenteric fistulas?
Test for hepatocellular carcinoma or germ cell neoplasm
Measure of distal intestinal function
test for Wilson's dz (decreased)
MC benign tumor
Vit K absorption is dependent on ?
Medium Chain Triglycerides transported via?
lymphoma exclusively in young males
MC genetic alteration in pancreatic CA
MC place for esophageal web
diarrhea, sm volume, guaiac pos
pancreatitis & perf ulcer referred pain?
Tx Entamoeba histolytica
H/o vomiting, then emesis turned bloody
MCC Small bowel obstruction
Serum Albumin - Ascitic Albumin >1.1
Laxative class: Bisacodyl and Senna
Laxative class: Polyethylene glycol
MC abx causing C. difficile overgrowth
inherited deficiency w/o cirrhosis - risk of HCC
Rx: competitively inhibits uptake transport protein (bilirubin)
Colonic dilation and toxic megacolon - risk of?
Location: annular with 'napkin-ring' constrictions and luminal obstruction
Invasion more in which adenomas?
Tumor arising from Interstitial Cells of Cajal
only human protozoa that lives in the duodenum
Dx: trypsinogen and trypsin not inactivated
Peritonitis - MC bacteria (besides E coli)
Dx: trypsin activity not inhibited
Rx that reduces portal blood flow
diarrhea type - sorbitol ingestion
MC location for pancreatic carcinoma
Key Tx for acute pancreatitis
charcot's + hypotension & change in mental status
Concentric peri-bile duct fibrosis
Given to get rid of ammonia in the GI tract
esophageal webs, iron deficiency anemia, glossitis, and koilonychias
remove GB, CBD, part of duodenum, HOP
Complete twisting of a loop of bowel
AR, HFE gene on chromsome 6
Test - Identifies lesions in distal 60cm
hallmark: surface epithelial damage w/ inc intraepithelial lymphocytes
liver dz: pruritis and elevated alk phos
Alarm sx or age > 50, should do?
Dx: intrinsic malignant obstruction of BD
MCC chronic liver test elevation (USA)
most widely used Rx for UC
Liver dz w/ inc NH3 and inc tendon reflexes
colorectal CA - highest incidence in?
more often with alcohol than NASH
MC type of esophageal CA
MC mesenchymal tumor of abd
omega sign on abd xray
macrophages crowd intestine + diarrhea, weight loss and malabsorption
Impacted gallstone in cystic duct

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