Science Quiz / 8b GUG

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QUIZ: Can you name the 8b GUG?

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QuestionAnswerNotes
#1 killer of neonates
Uterine size discrepant from dates
Mutation assoc w/ high grade endometrioid tumors
Perimenopausal uterine bleeding, first step?
proliferation marker in endometrial cycle
Condition during lactation, mimics inflammatory breast cancer
MC testicular tumor
Amniotic Fluid Index >90th %ile
Infection causing bladder CA
oligohydramnios and 'key hole' sign
Appendix testes remnant of ?
Endometrium that has been hormonally influenced by pregnancy
MCC Epididymal Orchitis in young men
6 months w/o period
Breast duct/lobule cells that produce milk
Origin of 90% ovarian cancers (aka MC form)
MCC abnml uterine bleeding in adolescence
MC trisomy in spontaneous abortion
MC breast carcinoma in situ
presence of endometrial glands in uterine myometrium
MCC male infertility in the world
reflex test to triage ASCUS pap smear in women > 21
Tx: stimulate ovary - induce endogenous FSH release
MC group of aneuploidy in spont ab
Still a cause of maternal and fetal death
Worst SE of Magnesium sulfate
Bilateral ovarian mets w/ signet ring
MC gynecologic CA
MC renal tumor
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Lady on tamoxifen w/ post-menopausal bleeding - next step?
low value w/ anovulation: failure to centrally stimulate follicular growth
Chromosome of BRCA-2
intraurethral Rx for ED
Endometrial glands/stroma implanted outside uterine cavity/walls
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Tx symptomatic bone mets (prostate CA)
Thin, long unilocular mass, associated with period
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
L1 proteins from HPV strains self-assemble into non-infectious units called?
MC STI
MC histiological subtype of endometrial CA
Type of cancer after tx for mediastinal mass in college age woman
Tx: antagonist in breast; agonist in endometrium
Targeted therapy for HER2+ breast CA
% of simple hyperplasia that progressed to cancer
Tx: tubal factor infertility
hormonal therapy of metastatic breast Ca causing chemical castration
MC histology of cervival CA
class of Rx for urge incontinence to tighten outlet
mech of finasteride, dutasteride
HTN dx in first 20 weeks of pregnancy
MCC abnml uterine bleeding in postmenopausal
Adnexal mass in reproductive age female, first r/o?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
acute infection w/ obstruction -1st step?
Progestin in BCPs derived from spironolactone
Cells that convert adrenal steroids to estrone
Chemo combo for advanced bladder CA
MC site of mets in metastatic breast cancer
'powder burn' lesions
Other name for ovarian fibroma
Removal of breast, pec minor and axillary lymph node
Mech: Change in transport speed of the ovum
Any condition irritating the periotoneal lining inc which marker?
Grading scheme for prostatic adenocarcinoma
postmenopausal, complex hyperplasia w/ atypia - tx?
Tx of choice for vaginal atrophy
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Rx w/ SE: endometrial polyps
Ovarian tumor w/ KRAS and BRAF mutations
exogenous testosterone leads to ? type of kidney stones
QuestionAnswerNotes
Main mode of spread of ovarian cancer
Malignant tumor of admixed proliferating trophoblasts, no villi
Induce fetal lung maturity - give mom ?
Composition of staghorn stone
malignant germ cell tumor: AFP
MC method of contraception
Colposcopy: cells w/ inc collagen turn white w/ ?
MC ovarian tumor (and cancer)
MC site of ectopic pregnant
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Higher percent of free PSA (25%+)
20-25% of adnexal masses, dx b/t age 10-30yo
Proper name for 'chocolate cyst'
Signet ring cells in ovary = ?
Dz: epidermis of nipple contains tumor cells
Most important reason fertility dec w/ female age is increasing ?
Flow of urine in retrograde fashion (to kidney) w/ voiding
best imaging modality for tubal infertility
Most important RF for uterine CA
Antigen that lyses seminal coagulum
Syndrome: AD w/ 85% penetrance, BRCA
Tumor marker for choriocarcinoma, embryonal carcinoma
Zone sampled in pap smear and biopsy
Appendix epididymis remnant of ?
e of incontinence: unstable bladder
hormone causing ovulation
beta 2 receptors cause uterine ?
Type of incontinence: outlet obstruction
MC site to endometriosis
umbilical cord inserts into the fetal membranes
Special type breast CA, high grade but good prognosis
ovarian neoplasm w/ 3 germinal layers
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MC aneuploidy in abortuses
Tumor from dense fibroconnective tissue of the breast
division of ovum after 13 days
Why is stage I breast Ca 10-year survival only 75%?
Best available protection against STIs
MC location of transitional cell cancer
Sv consequence of anovulatory cycle
HTN after 20 wk gestation assoc w/ proteinuria
Papillary projections surrounded by Schiller-Duval bodies
2nd most common primary site of mets to ovary
How to stage endometrial CA
MC Tx of superficial bladder cancer
Hallmark pathological finding of granulosa cell tumots
Permanent cessation of menses x1yr w/ high FSH, low E2
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
If surgery unavailable for testicular torson, reduce by twisting?
measure seminal vesciles - dilated due to?
antepartum hemorrhage after 20 wks
BPH Rx SE: orthostasis, dizziness, fall risk
Lowest contraceptive failure rates
Call-Exner bodies, Inhibin+
MC site of involvement in endometriosis
MC ovarian germ cell tumor
Type II endometrial carcinoma assoc w/ ?
Rx SE: PSA drops in half, ED, loss of libido
CA most strongly associated w/ obesity
dilatation of ducts, inspissated (thick) secretions
Abnormally deep implantation onto the myometrium
first line hormonal therapy of metastatic breast Ca in premenopausal
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
MC infiltrating breast Ca
Lab value inc if patient is not making sperm
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
MC neoplasm in young men
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
screening for nonpalpable breast masses
MC gynecological CA worldwide
bleeding but os is open or closed, but still viable pregnancy
sudden huge increase in PSA likely due to?
QuestionAnswerNotes
testicular torsion perinatal only
MC cystic mass in reproductive-age women
MC type of endometrial carcinoma
elevated seminal leukocyte count aka?
medical tx: urge incontinence
tx: stress urinary incontinence that inc sphincter tone
IUD c/i in Wilson's disease
normal strict morphology required to bind to?
Tx PUV: Incise valve to damage leaflet
Converts androgens to estrogen
malignant germ cell tumor: beta HCG
HTN after 20 wk w/o proteinuria
HRT: w/ uterus, need estrogen and ?
HPV: Degrades p53 in the host cell
trophoblastic proliferation, cystic villi, no fetal tissue
MCC testis CA >50yo
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Type of incontinence: neurogenic dysfunction
Chromosome 17, 85% lifetime breast Ca risk
% of complex atypical hyperplasia that progressed to cancer
monoclonal ab to HER-2 neu
MCC of amenorrhea (after pregnancy)
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
first line hormonal therapy of metastatic breast Ca in postmeno
HPV: Binds rB allowing for cell immortalization
pain with sex
implantation into cornu of uterus or lower uterine segment
Targeted therapy for ER+ breast CA
MCC UTO in male children
highest risk of prostate CA starting at what age?
MC tumor of myometrium
abnormal dev of chorionic villi in pregnancy can become?
hypogonadotropic hypogonadism and anosmia
Oral contraceptive in breastfeeding woman
male contraceptive = exogenous hormone?
intraabdominal pregnancy, later found in a 60yo woman
Sperm with DNA damage is assoc w/ ?
Prevent sz in preeclampsia
Stage: detected from elevated PSA alone, normal DRE & TRUS
Tumor marker for dysgerminoma
breast path - clown face
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Molecular? Type I, proliferative - simple hyperplasia
Bladder cancer sx in 85% of cases
Tumor marker of seminoma
% of simple atypical hyperplasia that progressed to cancer
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Penile CA 0% in men who are ?
% of complex hyperplasia that progressed to cancer
most prostate CA develops in which zone?
Most important prognostic factor in breast Ca
Molecular? Type I, simple - complex hyperplasia
Class of Rx for urge incontinence to dec contractility
Kidney CA stage T4, invades
Marker WT-1
trophoblastic proliferation, fetus or fetal tissue present
Mutation in mucinous ovarian tumors
C/I for anticholinergic therapy
Renal CA assoc w/ Von Hippel-Lindau
Tumor marker of stromal cell tumors
Most common estrogenic ovarian tumor
twins share chorion but one gets more blood flow
MC benign growth in breast
Rx: adjuvant therapy for postmenopausal breast Ca
pau d' orange, cancer cells in dermal lymphatics
Given to prevent CW recurrence at mastectomy site
'blue dot' sign and pain related to inflammation
Varicocele finding on U/S
Long acting Rx for ED
MC composition of kidney stones
Major SE of contraceptive implants

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