Science Quiz / 8b GUG

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QuestionAnswerNotes
Bilateral ovarian mets w/ signet ring
Proper name for 'chocolate cyst'
C/I for anticholinergic therapy
Prevent sz in preeclampsia
Rx: adjuvant therapy for postmenopausal breast Ca
highest risk of prostate CA starting at what age?
pain with sex
Appendix epididymis remnant of ?
HTN dx in first 20 weeks of pregnancy
Composition of staghorn stone
abnormal dev of chorionic villi in pregnancy can become?
Worst SE of Magnesium sulfate
best imaging modality for tubal infertility
MC Tx of superficial bladder cancer
% of complex hyperplasia that progressed to cancer
How to stage endometrial CA
6 months w/o period
#1 killer of neonates
Tx PUV: Incise valve to damage leaflet
Endometrial glands/stroma implanted outside uterine cavity/walls
Kidney CA stage T4, invades
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
tx: stress urinary incontinence that inc sphincter tone
Amniotic Fluid Index >90th %ile
MC gynecologic CA
MCC of amenorrhea (after pregnancy)
Antigen that lyses seminal coagulum
umbilical cord inserts into the fetal membranes
MC ovarian tumor (and cancer)
Tumor from dense fibroconnective tissue of the breast
bleeding but os is open or closed, but still viable pregnancy
Tumor marker of stromal cell tumors
screening for nonpalpable breast masses
Most important reason fertility dec w/ female age is increasing ?
Stage: detected from elevated PSA alone, normal DRE & TRUS
MC type of endometrial carcinoma
MC STI
Progestin in BCPs derived from spironolactone
ovarian neoplasm w/ 3 germinal layers
MC group of aneuploidy in spont ab
beta 2 receptors cause uterine ?
hypogonadotropic hypogonadism and anosmia
Rx: adjuvant therapy for ER+ premenopausal breast Ca
MC histology of cervival CA
trophoblastic proliferation, cystic villi, no fetal tissue
MC cystic mass in reproductive-age women
Type of incontinence: outlet obstruction
BPH Rx SE: orthostasis, dizziness, fall risk
Most important RF for uterine CA
exogenous testosterone leads to ? type of kidney stones
malignant germ cell tumor: AFP
presence of endometrial glands in uterine myometrium
MCC UTO in male children
MC composition of kidney stones
dilatation of ducts, inspissated (thick) secretions
Zone sampled in pap smear and biopsy
Colposcopy: cells w/ inc collagen turn white w/ ?
pau d' orange, cancer cells in dermal lymphatics
e of incontinence: unstable bladder
hormonal therapy of metastatic breast Ca causing chemical castration
normal strict morphology required to bind to?
Still a cause of maternal and fetal death
Removal of breast, pec minor and axillary lymph node
MC ovarian germ cell tumor
HTN after 20 wk gestation assoc w/ proteinuria
Condition during lactation, mimics inflammatory breast cancer
Marker WT-1
Bladder cancer sx in 85% of cases
first line hormonal therapy of metastatic breast Ca in premenopausal
HRT: w/ uterus, need estrogen and ?
first line hormonal therapy of metastatic breast Ca in postmeno
Grading scheme for prostatic adenocarcinoma
QuestionAnswerNotes
Endometrium that has been hormonally influenced by pregnancy
Tx symptomatic bone mets (prostate CA)
Perimenopausal uterine bleeding, first step?
MC site to endometriosis
implantation into cornu of uterus or lower uterine segment
% of complex atypical hyperplasia that progressed to cancer
breast path - clown face
reflex test to triage ASCUS pap smear in women > 21
CA most strongly associated w/ obesity
Appendix testes remnant of ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC breast carcinoma in situ
sudden huge increase in PSA likely due to?
Converts androgens to estrogen
Chromosome of BRCA-2
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
class of Rx for urge incontinence to tighten outlet
Long acting Rx for ED
Tx: tubal factor infertility
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
measure seminal vesciles - dilated due to?
male contraceptive = exogenous hormone?
Given to prevent CW recurrence at mastectomy site
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Lab value inc if patient is not making sperm
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Dz: epidermis of nipple contains tumor cells
Tumor marker for choriocarcinoma, embryonal carcinoma
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Tumor marker of seminoma
If surgery unavailable for testicular torson, reduce by twisting?
malignant germ cell tumor: beta HCG
Tumor marker for dysgerminoma
Main mode of spread of ovarian cancer
HPV: Degrades p53 in the host cell
MC site of involvement in endometriosis
Hallmark pathological finding of granulosa cell tumots
Origin of 90% ovarian cancers (aka MC form)
Tx: antagonist in breast; agonist in endometrium
% of simple hyperplasia that progressed to cancer
L1 proteins from HPV strains self-assemble into non-infectious units called?
Molecular? Type I, simple - complex hyperplasia
Oral contraceptive in breastfeeding woman
elevated seminal leukocyte count aka?
Type II endometrial carcinoma assoc w/ ?
Other name for ovarian fibroma
20-25% of adnexal masses, dx b/t age 10-30yo
2nd most common primary site of mets to ovary
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
'powder burn' lesions
MC tumor of myometrium
monoclonal ab to HER-2 neu
Permanent cessation of menses x1yr w/ high FSH, low E2
Breast duct/lobule cells that produce milk
Mutation in mucinous ovarian tumors
Chromosome 17, 85% lifetime breast Ca risk
MC method of contraception
division of ovum after 13 days
MC histiological subtype of endometrial CA
Type of cancer after tx for mediastinal mass in college age woman
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Targeted therapy for HER2+ breast CA
MC testicular tumor
MC trisomy in spontaneous abortion
Most common estrogenic ovarian tumor
HPV: Binds rB allowing for cell immortalization
% of simple atypical hyperplasia that progressed to cancer
Call-Exner bodies, Inhibin+
MC site of ectopic pregnant
QuestionAnswerNotes
Rx SE: PSA drops in half, ED, loss of libido
intraurethral Rx for ED
Mutation assoc w/ high grade endometrioid tumors
proliferation marker in endometrial cycle
Lowest contraceptive failure rates
Major SE of contraceptive implants
Best available protection against STIs
Why is stage I breast Ca 10-year survival only 75%?
Induce fetal lung maturity - give mom ?
Type of incontinence: neurogenic dysfunction
MCC Epididymal Orchitis in young men
Papillary projections surrounded by Schiller-Duval bodies
Special type breast CA, high grade but good prognosis
MC benign growth in breast
testicular torsion perinatal only
'blue dot' sign and pain related to inflammation
MC location of transitional cell cancer
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Rx w/ SE: endometrial polyps
Molecular? Type I, proliferative - simple hyperplasia
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
acute infection w/ obstruction -1st step?
Mech: Change in transport speed of the ovum
most prostate CA develops in which zone?
Most important prognostic factor in breast Ca
Chemo combo for advanced bladder CA
Adnexal mass in reproductive age female, first r/o?
MC aneuploidy in abortuses
MC infiltrating breast Ca
Cells that convert adrenal steroids to estrone
Sv consequence of anovulatory cycle
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
IUD c/i in Wilson's disease
MC site of mets in metastatic breast cancer
oligohydramnios and 'key hole' sign
Malignant tumor of admixed proliferating trophoblasts, no villi
Targeted therapy for ER+ breast CA
antepartum hemorrhage after 20 wks
Sperm with DNA damage is assoc w/ ?
Abnormally deep implantation onto the myometrium
Ovarian tumor w/ KRAS and BRAF mutations
Varicocele finding on U/S
Penile CA 0% in men who are ?
Flow of urine in retrograde fashion (to kidney) w/ voiding
MCC abnml uterine bleeding in postmenopausal
twins share chorion but one gets more blood flow
trophoblastic proliferation, fetus or fetal tissue present
Signet ring cells in ovary = ?
Class of Rx for urge incontinence to dec contractility
Syndrome: AD w/ 85% penetrance, BRCA
HTN after 20 wk w/o proteinuria
Tx: stimulate ovary - induce endogenous FSH release
low value w/ anovulation: failure to centrally stimulate follicular growth
Renal CA assoc w/ Von Hippel-Lindau
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
MCC male infertility in the world
Thin, long unilocular mass, associated with period
MC neoplasm in young men
intraabdominal pregnancy, later found in a 60yo woman
MCC abnml uterine bleeding in adolescence
Higher percent of free PSA (25%+)
medical tx: urge incontinence
hormone causing ovulation
Uterine size discrepant from dates
Infection causing bladder CA
postmenopausal, complex hyperplasia w/ atypia - tx?
Any condition irritating the periotoneal lining inc which marker?
MCC testis CA >50yo
MC gynecological CA worldwide
MC renal tumor
mech of finasteride, dutasteride
Tx of choice for vaginal atrophy

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Created Nov 17, 2012ReportNominate
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