Science Quiz / 8b GUG

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QuestionAnswerNotes
Tumor marker for endodermal sinus tumor, embryonal carcinoma
% of complex hyperplasia that progressed to cancer
MCC male infertility in the world
hormone causing ovulation
% of simple hyperplasia that progressed to cancer
MCC testis CA >50yo
Origin of 90% ovarian cancers (aka MC form)
Any condition irritating the periotoneal lining inc which marker?
Composition of staghorn stone
testicular torsion perinatal only
reflex test to triage ASCUS pap smear in women > 21
twins share chorion but one gets more blood flow
% of complex atypical hyperplasia that progressed to cancer
MC composition of kidney stones
HPV: Degrades p53 in the host cell
CA most strongly associated w/ obesity
Tumor marker for dysgerminoma
Bladder cancer sx in 85% of cases
pain with sex
Tumor from dense fibroconnective tissue of the breast
Tumor marker of seminoma
division of ovum after 13 days
#1 killer of neonates
Uterine size discrepant from dates
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
measure seminal vesciles - dilated due to?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Most important prognostic factor in breast Ca
bleeding but os is open or closed, but still viable pregnancy
Syndrome: AD w/ 85% penetrance, BRCA
Major SE of contraceptive implants
Tx PUV: Incise valve to damage leaflet
Rx SE: PSA drops in half, ED, loss of libido
Endometrial glands/stroma implanted outside uterine cavity/walls
MC gynecological CA worldwide
tx: stress urinary incontinence that inc sphincter tone
Rx w/ SE: endometrial polyps
male contraceptive = exogenous hormone?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
MC neoplasm in young men
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Hallmark pathological finding of granulosa cell tumots
ovarian neoplasm w/ 3 germinal layers
Marker WT-1
MC tumor of myometrium
MC site of ectopic pregnant
Kidney CA stage T4, invades
best imaging modality for tubal infertility
Most common estrogenic ovarian tumor
MC histology of cervival CA
MC site of mets in metastatic breast cancer
intraurethral Rx for ED
Endometrium that has been hormonally influenced by pregnancy
postmenopausal, complex hyperplasia w/ atypia - tx?
Progestin in BCPs derived from spironolactone
Tx: antagonist in breast; agonist in endometrium
Prevent sz in preeclampsia
Oral contraceptive in breastfeeding woman
MC renal tumor
breast path - clown face
screening for nonpalpable breast masses
Type of cancer after tx for mediastinal mass in college age woman
Type II endometrial carcinoma assoc w/ ?
HTN after 20 wk gestation assoc w/ proteinuria
umbilical cord inserts into the fetal membranes
Induce fetal lung maturity - give mom ?
Worst SE of Magnesium sulfate
Papillary projections surrounded by Schiller-Duval bodies
pau d' orange, cancer cells in dermal lymphatics
MC ovarian tumor (and cancer)
MC histiological subtype of endometrial CA
Flow of urine in retrograde fashion (to kidney) w/ voiding
QuestionAnswerNotes
6 months w/o period
Thin, long unilocular mass, associated with period
Cells that convert adrenal steroids to estrone
HTN dx in first 20 weeks of pregnancy
MC type of endometrial carcinoma
Removal of breast, pec minor and axillary lymph node
Adnexal mass in reproductive age female, first r/o?
Stage: detected from elevated PSA alone, normal DRE & TRUS
Chemo combo for advanced bladder CA
HPV: Binds rB allowing for cell immortalization
Mutation assoc w/ high grade endometrioid tumors
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Most important RF for uterine CA
intraabdominal pregnancy, later found in a 60yo woman
first line hormonal therapy of metastatic breast Ca in premenopausal
MC aneuploidy in abortuses
MC group of aneuploidy in spont ab
Sv consequence of anovulatory cycle
Lady on tamoxifen w/ post-menopausal bleeding - next step?
MC testicular tumor
Sperm with DNA damage is assoc w/ ?
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Higher percent of free PSA (25%+)
Rx: adjuvant therapy for postmenopausal breast Ca
IUD c/i in Wilson's disease
trophoblastic proliferation, cystic villi, no fetal tissue
MC infiltrating breast Ca
class of Rx for urge incontinence to tighten outlet
monoclonal ab to HER-2 neu
MC site of involvement in endometriosis
MC trisomy in spontaneous abortion
'powder burn' lesions
Tumor marker of stromal cell tumors
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
2nd most common primary site of mets to ovary
Mutation in mucinous ovarian tumors
Mech: Change in transport speed of the ovum
Lowest contraceptive failure rates
MCC Epididymal Orchitis in young men
Proper name for 'chocolate cyst'
MC gynecologic CA
antepartum hemorrhage after 20 wks
Molecular? Type I, simple - complex hyperplasia
MC benign growth in breast
exogenous testosterone leads to ? type of kidney stones
acute infection w/ obstruction -1st step?
Chromosome of BRCA-2
MC ovarian germ cell tumor
C/I for anticholinergic therapy
Class of Rx for urge incontinence to dec contractility
Molecular? Type I, proliferative - simple hyperplasia
Appendix testes remnant of ?
dilatation of ducts, inspissated (thick) secretions
L1 proteins from HPV strains self-assemble into non-infectious units called?
Tumor marker for choriocarcinoma, embryonal carcinoma
Chromosome 17, 85% lifetime breast Ca risk
Most important reason fertility dec w/ female age is increasing ?
MCC UTO in male children
20-25% of adnexal masses, dx b/t age 10-30yo
MC method of contraception
Infection causing bladder CA
MCC abnml uterine bleeding in postmenopausal
MC STI
low value w/ anovulation: failure to centrally stimulate follicular growth
MC location of transitional cell cancer
Given to prevent CW recurrence at mastectomy site
MC cystic mass in reproductive-age women
normal strict morphology required to bind to?
Abnormally deep implantation onto the myometrium
sudden huge increase in PSA likely due to?
trophoblastic proliferation, fetus or fetal tissue present
Targeted therapy for HER2+ breast CA
QuestionAnswerNotes
mech of finasteride, dutasteride
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Lab value inc if patient is not making sperm
HRT: w/ uterus, need estrogen and ?
MC Tx of superficial bladder cancer
Perimenopausal uterine bleeding, first step?
Malignant tumor of admixed proliferating trophoblasts, no villi
Penile CA 0% in men who are ?
Breast duct/lobule cells that produce milk
How to stage endometrial CA
Type of incontinence: outlet obstruction
Best available protection against STIs
Ovarian tumor w/ KRAS and BRAF mutations
Still a cause of maternal and fetal death
Tx symptomatic bone mets (prostate CA)
Main mode of spread of ovarian cancer
Long acting Rx for ED
BPH Rx SE: orthostasis, dizziness, fall risk
Varicocele finding on U/S
Renal CA assoc w/ Von Hippel-Lindau
most prostate CA develops in which zone?
HTN after 20 wk w/o proteinuria
Dz: epidermis of nipple contains tumor cells
e of incontinence: unstable bladder
Zone sampled in pap smear and biopsy
first line hormonal therapy of metastatic breast Ca in postmeno
If surgery unavailable for testicular torson, reduce by twisting?
hormonal therapy of metastatic breast Ca causing chemical castration
Type of incontinence: neurogenic dysfunction
Special type breast CA, high grade but good prognosis
Appendix epididymis remnant of ?
highest risk of prostate CA starting at what age?
medical tx: urge incontinence
oligohydramnios and 'key hole' sign
MC breast carcinoma in situ
malignant germ cell tumor: AFP
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
abnormal dev of chorionic villi in pregnancy can become?
Signet ring cells in ovary = ?
Tx: tubal factor infertility
Converts androgens to estrogen
Other name for ovarian fibroma
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
MCC abnml uterine bleeding in adolescence
Condition during lactation, mimics inflammatory breast cancer
implantation into cornu of uterus or lower uterine segment
Antigen that lyses seminal coagulum
Permanent cessation of menses x1yr w/ high FSH, low E2
MCC of amenorrhea (after pregnancy)
beta 2 receptors cause uterine ?
hypogonadotropic hypogonadism and anosmia
elevated seminal leukocyte count aka?
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Bilateral ovarian mets w/ signet ring
proliferation marker in endometrial cycle
Why is stage I breast Ca 10-year survival only 75%?
'blue dot' sign and pain related to inflammation
Tx: stimulate ovary - induce endogenous FSH release
Colposcopy: cells w/ inc collagen turn white w/ ?
Tx of choice for vaginal atrophy
Rx: adjuvant therapy for ER+ premenopausal breast Ca
presence of endometrial glands in uterine myometrium
Call-Exner bodies, Inhibin+
Amniotic Fluid Index >90th %ile
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
malignant germ cell tumor: beta HCG
Grading scheme for prostatic adenocarcinoma
% of simple atypical hyperplasia that progressed to cancer
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Targeted therapy for ER+ breast CA
MC site to endometriosis

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Created Nov 17, 2012ReportNominate
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