Science Quiz / 8b GUG

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Can you name the 8b GUG?

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IUD c/i in Wilson's disease
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
monoclonal ab to HER-2 neu
Syndrome: AD w/ 85% penetrance, BRCA
MC renal tumor
Uterine size discrepant from dates
MC type of endometrial carcinoma
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
hormone causing ovulation
Given to prevent CW recurrence at mastectomy site
Adnexal mass in reproductive age female, first r/o?
Composition of staghorn stone
hormonal therapy of metastatic breast Ca causing chemical castration
MC method of contraception
C/I for anticholinergic therapy
e of incontinence: unstable bladder
first line hormonal therapy of metastatic breast Ca in premenopausal
MC aneuploidy in abortuses
Thin, long unilocular mass, associated with period
medical tx: urge incontinence
Progestin in BCPs derived from spironolactone
division of ovum after 13 days
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Most important prognostic factor in breast Ca
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
class of Rx for urge incontinence to tighten outlet
CA most strongly associated w/ obesity
'powder burn' lesions
'blue dot' sign and pain related to inflammation
Type of cancer after tx for mediastinal mass in college age woman
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Most important RF for uterine CA
Grading scheme for prostatic adenocarcinoma
Oral contraceptive in breastfeeding woman
MC tumor of myometrium
Tx: tubal factor infertility
Molecular? Type I, proliferative - simple hyperplasia
MCC male infertility in the world
Signet ring cells in ovary = ?
MC site of involvement in endometriosis
MC site of ectopic pregnant
#1 killer of neonates
Ovarian tumor w/ KRAS and BRAF mutations
Type of incontinence: neurogenic dysfunction
Condition during lactation, mimics inflammatory breast cancer
Chromosome 17, 85% lifetime breast Ca risk
oligohydramnios and 'key hole' sign
Prevent sz in preeclampsia
intraabdominal pregnancy, later found in a 60yo woman
% of simple atypical hyperplasia that progressed to cancer
Colposcopy: cells w/ inc collagen turn white w/ ?
bleeding but os is open or closed, but still viable pregnancy
Chemo combo for advanced bladder CA
Best available protection against STIs
MC histiological subtype of endometrial CA
Major SE of contraceptive implants
BPH Rx SE: orthostasis, dizziness, fall risk
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Papillary projections surrounded by Schiller-Duval bodies
implantation into cornu of uterus or lower uterine segment
acute infection w/ obstruction -1st step?
Malignant tumor of admixed proliferating trophoblasts, no villi
presence of endometrial glands in uterine myometrium
Molecular? Type I, simple - complex hyperplasia
Marker WT-1
MC trisomy in spontaneous abortion
umbilical cord inserts into the fetal membranes
How to stage endometrial CA
MC neoplasm in young men
Tx PUV: Incise valve to damage leaflet
Tx of choice for vaginal atrophy
Class of Rx for urge incontinence to dec contractility
Lowest contraceptive failure rates
Type of incontinence: outlet obstruction
ovarian neoplasm w/ 3 germinal layers
Mech: Change in transport speed of the ovum
MCC abnml uterine bleeding in adolescence
Penile CA 0% in men who are ?
Permanent cessation of menses x1yr w/ high FSH, low E2
MC site to endometriosis
MC breast carcinoma in situ
male contraceptive = exogenous hormone?
Appendix testes remnant of ?
MC infiltrating breast Ca
exogenous testosterone leads to ? type of kidney stones
malignant germ cell tumor: AFP
Stage: detected from elevated PSA alone, normal DRE & TRUS
breast path - clown face
HTN after 20 wk w/o proteinuria
Targeted therapy for ER+ breast CA
MCC testis CA >50yo
Targeted therapy for HER2+ breast CA
L1 proteins from HPV strains self-assemble into non-infectious units called?
2nd most common primary site of mets to ovary
Cells that convert adrenal steroids to estrone
Amniotic Fluid Index >90th %ile
MC group of aneuploidy in spont ab
Antigen that lyses seminal coagulum
6 months w/o period
Kidney CA stage T4, invades
Zone sampled in pap smear and biopsy
best imaging modality for tubal infertility
MC gynecologic CA
Long acting Rx for ED
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
twins share chorion but one gets more blood flow
Mutation assoc w/ high grade endometrioid tumors
antepartum hemorrhage after 20 wks
Type II endometrial carcinoma assoc w/ ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
HPV: Degrades p53 in the host cell
Bilateral ovarian mets w/ signet ring
Tx: antagonist in breast; agonist in endometrium
Endometrium that has been hormonally influenced by pregnancy
Bladder cancer sx in 85% of cases
Rx w/ SE: endometrial polyps
testicular torsion perinatal only
Most important reason fertility dec w/ female age is increasing ?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Tumor marker of seminoma
abnormal dev of chorionic villi in pregnancy can become?
% of complex hyperplasia that progressed to cancer
Perimenopausal uterine bleeding, first step?
Endometrial glands/stroma implanted outside uterine cavity/walls
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Renal CA assoc w/ Von Hippel-Lindau
Converts androgens to estrogen
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Any condition irritating the periotoneal lining inc which marker?
HTN dx in first 20 weeks of pregnancy
Tumor marker for endodermal sinus tumor, embryonal carcinoma
MC gynecological CA worldwide
Dz: epidermis of nipple contains tumor cells
Higher percent of free PSA (25%+)
20-25% of adnexal masses, dx b/t age 10-30yo
Worst SE of Magnesium sulfate
trophoblastic proliferation, fetus or fetal tissue present
MC histology of cervival CA
MC Tx of superficial bladder cancer
Tumor marker for choriocarcinoma, embryonal carcinoma
HRT: w/ uterus, need estrogen and ?
Special type breast CA, high grade but good prognosis
sudden huge increase in PSA likely due to?
trophoblastic proliferation, cystic villi, no fetal tissue
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Tx: stimulate ovary - induce endogenous FSH release
Chromosome of BRCA-2
tx: stress urinary incontinence that inc sphincter tone
Still a cause of maternal and fetal death
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Flow of urine in retrograde fashion (to kidney) w/ voiding
normal strict morphology required to bind to?
MC cystic mass in reproductive-age women
hypogonadotropic hypogonadism and anosmia
intraurethral Rx for ED
measure seminal vesciles - dilated due to?
MC location of transitional cell cancer
If surgery unavailable for testicular torson, reduce by twisting?
Rx: adjuvant therapy for postmenopausal breast Ca
beta 2 receptors cause uterine ?
% of simple hyperplasia that progressed to cancer
Hallmark pathological finding of granulosa cell tumots
HPV: Binds rB allowing for cell immortalization
MC ovarian germ cell tumor
reflex test to triage ASCUS pap smear in women > 21
MC composition of kidney stones
postmenopausal, complex hyperplasia w/ atypia - tx?
MCC Epididymal Orchitis in young men
Sv consequence of anovulatory cycle
Main mode of spread of ovarian cancer
proliferation marker in endometrial cycle
Most common estrogenic ovarian tumor
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
malignant germ cell tumor: beta HCG
% of complex atypical hyperplasia that progressed to cancer
mech of finasteride, dutasteride
Call-Exner bodies, Inhibin+
MCC abnml uterine bleeding in postmenopausal
Tumor marker for dysgerminoma
MCC of amenorrhea (after pregnancy)
elevated seminal leukocyte count aka?
most prostate CA develops in which zone?
Mutation in mucinous ovarian tumors
MC testicular tumor
pau d' orange, cancer cells in dermal lymphatics
Rx SE: PSA drops in half, ED, loss of libido
Lab value inc if patient is not making sperm
Tumor from dense fibroconnective tissue of the breast
MC site of mets in metastatic breast cancer
Removal of breast, pec minor and axillary lymph node
low value w/ anovulation: failure to centrally stimulate follicular growth
Infection causing bladder CA
Why is stage I breast Ca 10-year survival only 75%?
Varicocele finding on U/S
Breast duct/lobule cells that produce milk
MCC UTO in male children
highest risk of prostate CA starting at what age?
Tx symptomatic bone mets (prostate CA)
Assoc w/ uterine hyperplasia/CA in postmenopausal women
MC benign growth in breast
Other name for ovarian fibroma
dilatation of ducts, inspissated (thick) secretions
HTN after 20 wk gestation assoc w/ proteinuria
Origin of 90% ovarian cancers (aka MC form)
screening for nonpalpable breast masses
Sperm with DNA damage is assoc w/ ?
first line hormonal therapy of metastatic breast Ca in postmeno
Tumor marker of stromal cell tumors
Proper name for 'chocolate cyst'
Appendix epididymis remnant of ?
pain with sex
MC ovarian tumor (and cancer)
Abnormally deep implantation onto the myometrium
Induce fetal lung maturity - give mom ?
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs

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