Science Quiz / 8b GUG

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MC infiltrating breast Ca
BPH Rx SE: orthostasis, dizziness, fall risk
measure seminal vesciles - dilated due to?
proliferation marker in endometrial cycle
Bladder cancer sx in 85% of cases
Any condition irritating the periotoneal lining inc which marker?
MC gynecologic CA
abnormal dev of chorionic villi in pregnancy can become?
Most important prognostic factor in breast Ca
Molecular? Type I, proliferative - simple hyperplasia
Mutation assoc w/ high grade endometrioid tumors
% of complex atypical hyperplasia that progressed to cancer
Rx: adjuvant therapy for ER+ premenopausal breast Ca
most prostate CA develops in which zone?
Type of cancer after tx for mediastinal mass in college age woman
Appendix epididymis remnant of ?
Tx symptomatic bone mets (prostate CA)
MC histology of cervival CA
% of complex hyperplasia that progressed to cancer
trophoblastic proliferation, cystic villi, no fetal tissue
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Syndrome: AD w/ 85% penetrance, BRCA
highest risk of prostate CA starting at what age?
Marker WT-1
HTN after 20 wk w/o proteinuria
Bilateral ovarian mets w/ signet ring
Tx: tubal factor infertility
Amniotic Fluid Index >90th %ile
Renal CA assoc w/ Von Hippel-Lindau
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
bleeding but os is open or closed, but still viable pregnancy
acute infection w/ obstruction -1st step?
Progestin in BCPs derived from spironolactone
Rx: adjuvant therapy for postmenopausal breast Ca
MC ovarian tumor (and cancer)
Given to prevent CW recurrence at mastectomy site
HRT: w/ uterus, need estrogen and ?
Higher percent of free PSA (25%+)
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
L1 proteins from HPV strains self-assemble into non-infectious units called?
intraurethral Rx for ED
Kidney CA stage T4, invades
MC benign growth in breast
ovarian neoplasm w/ 3 germinal layers
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
testicular torsion perinatal only
Call-Exner bodies, Inhibin+
CA most strongly associated w/ obesity
first line hormonal therapy of metastatic breast Ca in premenopausal
MC site to endometriosis
low value w/ anovulation: failure to centrally stimulate follicular growth
% of simple hyperplasia that progressed to cancer
MC gynecological CA worldwide
hypogonadotropic hypogonadism and anosmia
normal strict morphology required to bind to?
Targeted therapy for ER+ breast CA
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
pain with sex
Mech: Change in transport speed of the ovum
MC site of involvement in endometriosis
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MCC UTO in male children
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Uterine size discrepant from dates
Main mode of spread of ovarian cancer
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Most important reason fertility dec w/ female age is increasing ?
Tx: stimulate ovary - induce endogenous FSH release
MC tumor of myometrium
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
division of ovum after 13 days
Tx of choice for vaginal atrophy
Cells that convert adrenal steroids to estrone
Condition during lactation, mimics inflammatory breast cancer
Most important RF for uterine CA
Perimenopausal uterine bleeding, first step?
malignant germ cell tumor: AFP
antepartum hemorrhage after 20 wks
MC histiological subtype of endometrial CA
pau d' orange, cancer cells in dermal lymphatics
Type of incontinence: outlet obstruction
Tumor marker for dysgerminoma
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
reflex test to triage ASCUS pap smear in women > 21
Penile CA 0% in men who are ?
MCC testis CA >50yo
hormone causing ovulation
trophoblastic proliferation, fetus or fetal tissue present
screening for nonpalpable breast masses
MC site of mets in metastatic breast cancer
Thin, long unilocular mass, associated with period
hormonal therapy of metastatic breast Ca causing chemical castration
Abnormally deep implantation onto the myometrium
'blue dot' sign and pain related to inflammation
Papillary projections surrounded by Schiller-Duval bodies
Chromosome 17, 85% lifetime breast Ca risk
MC location of transitional cell cancer
Chemo combo for advanced bladder CA
Tumor marker of seminoma
monoclonal ab to HER-2 neu
HPV: Binds rB allowing for cell immortalization
Converts androgens to estrogen
medical tx: urge incontinence
MCC of amenorrhea (after pregnancy)
Composition of staghorn stone
Removal of breast, pec minor and axillary lymph node
Sv consequence of anovulatory cycle
Type of incontinence: neurogenic dysfunction
Worst SE of Magnesium sulfate
% of simple atypical hyperplasia that progressed to cancer
MC trisomy in spontaneous abortion
malignant germ cell tumor: beta HCG
first line hormonal therapy of metastatic breast Ca in postmeno
Lowest contraceptive failure rates
male contraceptive = exogenous hormone?
Oral contraceptive in breastfeeding woman
Tx: antagonist in breast; agonist in endometrium
Flow of urine in retrograde fashion (to kidney) w/ voiding
class of Rx for urge incontinence to tighten outlet
Special type breast CA, high grade but good prognosis
MC renal tumor
Stage: detected from elevated PSA alone, normal DRE & TRUS
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
exogenous testosterone leads to ? type of kidney stones
Induce fetal lung maturity - give mom ?
Major SE of contraceptive implants
Other name for ovarian fibroma
Prevent sz in preeclampsia
elevated seminal leukocyte count aka?
Zone sampled in pap smear and biopsy
Breast duct/lobule cells that produce milk
#1 killer of neonates
e of incontinence: unstable bladder
intraabdominal pregnancy, later found in a 60yo woman
umbilical cord inserts into the fetal membranes
Most common estrogenic ovarian tumor
2nd most common primary site of mets to ovary
Sperm with DNA damage is assoc w/ ?
beta 2 receptors cause uterine ?
Malignant tumor of admixed proliferating trophoblasts, no villi
Long acting Rx for ED
Tumor marker of stromal cell tumors
presence of endometrial glands in uterine myometrium
6 months w/o period
Class of Rx for urge incontinence to dec contractility
If surgery unavailable for testicular torson, reduce by twisting?
Endometrial glands/stroma implanted outside uterine cavity/walls
Colposcopy: cells w/ inc collagen turn white w/ ?
HTN dx in first 20 weeks of pregnancy
postmenopausal, complex hyperplasia w/ atypia - tx?
Tx PUV: Incise valve to damage leaflet
HPV: Degrades p53 in the host cell
20-25% of adnexal masses, dx b/t age 10-30yo
MCC male infertility in the world
MC ovarian germ cell tumor
Proper name for 'chocolate cyst'
MCC abnml uterine bleeding in adolescence
MC breast carcinoma in situ
Varicocele finding on U/S
sudden huge increase in PSA likely due to?
Chromosome of BRCA-2
Mutation in mucinous ovarian tumors
Ovarian tumor w/ KRAS and BRAF mutations
oligohydramnios and 'key hole' sign
implantation into cornu of uterus or lower uterine segment
mech of finasteride, dutasteride
Lady on tamoxifen w/ post-menopausal bleeding - next step?
dilatation of ducts, inspissated (thick) secretions
Appendix testes remnant of ?
Still a cause of maternal and fetal death
Signet ring cells in ovary = ?
Infection causing bladder CA
Targeted therapy for HER2+ breast CA
breast path - clown face
MC composition of kidney stones
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC Tx of superficial bladder cancer
MC method of contraception
Endometrium that has been hormonally influenced by pregnancy
Dz: epidermis of nipple contains tumor cells
Antigen that lyses seminal coagulum
MC cystic mass in reproductive-age women
best imaging modality for tubal infertility
Origin of 90% ovarian cancers (aka MC form)
MC aneuploidy in abortuses
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Hallmark pathological finding of granulosa cell tumots
Best available protection against STIs
How to stage endometrial CA
Adnexal mass in reproductive age female, first r/o?
C/I for anticholinergic therapy
Grading scheme for prostatic adenocarcinoma
MC type of endometrial carcinoma
MCC abnml uterine bleeding in postmenopausal
'powder burn' lesions
IUD c/i in Wilson's disease
MC site of ectopic pregnant
Tumor from dense fibroconnective tissue of the breast
Type II endometrial carcinoma assoc w/ ?
Rx SE: PSA drops in half, ED, loss of libido
Why is stage I breast Ca 10-year survival only 75%?
MC testicular tumor
twins share chorion but one gets more blood flow
Molecular? Type I, simple - complex hyperplasia
Rx w/ SE: endometrial polyps
Permanent cessation of menses x1yr w/ high FSH, low E2
MCC Epididymal Orchitis in young men
MC group of aneuploidy in spont ab
MC neoplasm in young men
Tumor marker for choriocarcinoma, embryonal carcinoma
Lab value inc if patient is not making sperm
HTN after 20 wk gestation assoc w/ proteinuria
tx: stress urinary incontinence that inc sphincter tone

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