Science Quiz / 8b Endocrine1

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Can you name the 8b Endocrine1?

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Hyponatremia w/ hypoosmolarity, euvolemic
Adrenal layer - cortisol (less), DHEA, androstenedione
aging causes which testicular deficiency?
Adrenal layer - cortisol (more)
prolactinoma sx but low serum prolactin due to?
SE: 2nd aldosterone deficiency - besides BB and NSAID
Test to Dx DI
Test to eval thyroid nodule/mass for malignancy
MCC secondary aldosterone deficiency
Marijuana and methadone cause gynecomastia by dec ?
48 hrs of Dex differentiates Cushing's from ?
Old test used to evalutate binding proteins
how to tell organic from psychogenic ED
anosmia and lack of secual development
MCC tertiary adrenal insufficiency
Test for dec feedback inhibition of cortisol
Psychoactive agent that can cause gynecomastia
cafe-au-lait spots, precocious puberty, acromegaly, thyrotoxicosis
dopamine agonist w/ SE: nausea, orthostasis
ID Rx w/ SE of nephrogenic DI
Baby w/ Na wasting, hypovolemia, hyperkalemia, very high aldo
Adrenalytic Rx that can elevate liver enzymes
Hormone - dev of epididymis, vas def, seminal vesicle
Test for overproduction of cortisol
MC pituitary lesion
Gynecomastia w/ Inc LH, Dec T
Test for non-toxic MNG
primary AI effect on renin?
Acts via cyclic AMP to inc permability of the tubular cell to water
Prolactin is excreted by ?
Hyperthryoidism w/ very high mortality
primary testicular failure - low testosterone, ? LH
Rx class: flutamide, finasteride, dutasteride
priamry adrenal insuff - BUN goes ?
testicle in inguinal canal, undeveloped
Gynecomastia w/ Inc LH, Inc T, dec TSH
Endogenous cause for low RAIU w/ hyperthyroid sx
Hemorrhage into pituitary - aka?
dx: tufting of terminal phalanges
Tx: secondary and tertiry AI
AMH, inhibin, activins, and aromatase secreted by?
ADH secreted by the ?
Test to evaluate thyroid nodularity
T3/T4 are bound by albumin, TBG, and ?
MCC goiter and hypothyroid in US
Worst form of Thyroid Ca
Thyroid Ca that invades blood vessels early
Hyperthalamic temp instability w/ alt fevers
post adrenalectomy - risk of ?
5-alpha-reductase converts testosterone to ?
MC thyroid Ca
Painless hyperthyroid -> hypothyroid that resolves after a year
Psych Rx w/ SE of nephrogenic DI
hormone - dev of prostate, ext genitalia
Adrenal layer - aldosterone
Tx: goiter w/ compressive sx in unhealthy individuals
p450 cleaves cholesterol side chains to make?
Elevated prolactin w/o clinical sx, lab should do?
Acromegaly - MCC death due to enlargement of?
Tx for central DI
Size of adrenals w/ autoimmune dz
Test for HPA axis or GH axis deficiency
DI-like sx but inc AVP w/ water deprivation and doesnt respond to DDAVP
Inhibin from sertoli cells inhibits GnRH and ?
hypothalamus is derived from the ?
Rx that causes goiter in 6% of chronic users
iodide is stored w/i thyroid as?
ACTH dependent - next test?
Lack of ?results in impermeability of collecting duct to water/marked diuresis
male w/ female phenotype, lack axillary/pubic hair
Rate limiting step for thyroid hormone synthesis
DM, optic atrophy, deafness - also expect what sx?
Diffuse toxic goiter on RAIU (hot) - dx?
Ending of Rx to tx: SIADH
High estrogen states effect on TBG?
Test to dx papillary thyroid Ca
effect of insulin resistance on sex hormone binding globulin (SHBG)
Exophthalmos, lytic bone lesions, DI
Rx: Inhibits growth hormone
1st tx for Thyroid Storm
Reduction in thyroid hormone levels from ingesting large amt iodine
Pituitary adenoma, Parathyroid hyperplasia, Pancreatic neuroendocrine tumors
First test to check for acromegaly
In which gender is thyroid malignancy w/ nodule more likely?
mediates most of the effects of GH on somatic growth
unique enzyme in glomerularis
Gynecomastia w/ nml LH, Dec T, nl PRL
Elevated GH/IGF-1 not suppressed by oral glucose tolerance test
Blue nevi, cardiac myxomas, schwannoma, testicle/ovary tumor
Rx that greatly increases iodine
Small but firm testicles - dx?
Insulin tolerance test c/i in pt w/ sz and ?
toxic adenoma: tx in US w/ cure rate > 80%
Measured to release vasopressin at anterolateral hypothalamus
Measured to release vasopressin at carotid sinus and aortic arch
Visual field defect w/ pituitary mass
unexplained hyperkalemia, age > 60
androgen deficient in third trimester - sx?
Hypothyroidism w/ very high mortality
Neoplasia of the parafollicular cell
how does hyperprolactinemia cause gynecomastia
Gynecomastia w/ Inc LH, Inc T, nml TSH
Tx acromegaly, failing somatostatin analogues
MCC thyrotoxicosis
Adrenal dz caused by sarcoidosis
growth of lower jaw
phenotype switches from female to male at puberty
Acute or subacute thyroiditis: RAIU normal
Satiety signal
21-hydroxylase deficiency aka?
dopamine receptor agonist
Useful for thyroid Ca surveillance post surgery and radioiodine ablation
Dx: CRH stim -> exaggerated rise in ACTH
weakness, N/V, weight loss, hyperpigmentation, vitiligo, orthostatic hypotension
AR dz involving epithelial Na channel
Gold standard for dx of adrenal insufficiency
After pituitary surgery, change in water balance due to no?
Tumor from Rathke's pouch
Way to measure central ACTH
Leydig cells produce which hormone?
2nd adrenal insufficiency lacks?
2nd adrenal insuff at delivery, in women w/ significant blood loss
primary adrenal insuff - Na goes ?
MCC acute thyroiditis (category)
Abnml migration of GnRH and olfactory neurons
acid base disturbance caused by 2nd hypoaldosteronism
hyperpigmentation, striae, truncal obesity, hyperandrogenism
testosterone level in androgen resistance syndromes
bioavailable testosterone is NOT bound to?
Stimulates w/ CRH, suppresses w/ high dose Dex
MCC painful thyroid goiter
adenohypophysis (ant pit) develops from?
Gynecomastia w/ inc hcg - concern for ?
Inheritance of Kallman's syndrome
Hormone imp for parturation and lactation?
men, permanent virilization of the hypothalamus occurs?
only synthetic corticosteroid not tested by the cortisol assay
low 8am cortisol, high ACTH
escutcheon type - androgen deficient after puberty
High androgen states effect on TBG?
endocrine condition w/ absolute eosinophilia
Test for lack of diurnal rhythm of cortisol
Test to assess functional status of thyroid tissue
Type of DI w/ high ADH
polydipsia, polyuria, large urine volume, inappropriately dilute urine
Dx: high ESR, low TSH, High T4 >T3, Low anti=TPO/Tgb
Cortisol + 11-beta-hydroxysteroid dehydrogenase = ?
The only pituitary adenoma where surgery is not considered first-line
Effect of amiodarone on RAIU
Painless woody goiter and sclerosing cholangitis
Common precursor increases prolactin due to decreased?
SE: prim aldosterone deficiency - besides ACEI/ARBs
skeleton type - androgen deficient before puberty?
HTN in Cushing's b/c cortisol activates the ? receptor
Abnormal bend of penis during erection
Secondary amenorrhea after D&C
male breast enlargement caused by inc dipose tissue
Rx: Graves Dz (non-compressive)
CRH does not stimulate, High Dose Dex does not suppress
MCC primary adrenal insuff in western world
elderly w/ weight loss, anorexia, constipation, tachy, afib, cognitive dysfunction
Vaccine preventable cause of acquired testicular damage
Rx: block MR receptor
Persistent hyperkalemia w/o obv cause

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Created Nov 12, 2012ReportNominate
Tags:endocrine, note

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