Science Quiz / 8b Endocrine1

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Can you name the 8b Endocrine1?

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QuestionAnswerNotes
low 8am cortisol, high ACTH
phenotype switches from female to male at puberty
AMH, inhibin, activins, and aromatase secreted by?
Test to eval thyroid nodule/mass for malignancy
male breast enlargement caused by inc dipose tissue
Hormone imp for parturation and lactation?
testosterone level in androgen resistance syndromes
1st tx for Thyroid Storm
Old test used to evalutate binding proteins
Abnormal bend of penis during erection
Rx: Graves Dz (non-compressive)
Endogenous cause for low RAIU w/ hyperthyroid sx
Type of DI w/ high ADH
MCC acute thyroiditis (category)
Stimulates w/ CRH, suppresses w/ high dose Dex
Visual field defect w/ pituitary mass
Prolactin is excreted by ?
Secondary amenorrhea after D&C
Tumor from Rathke's pouch
adenohypophysis (ant pit) develops from?
Test for non-toxic MNG
Size of adrenals w/ autoimmune dz
High androgen states effect on TBG?
Baby w/ Na wasting, hypovolemia, hyperkalemia, very high aldo
SE: 2nd aldosterone deficiency - besides BB and NSAID
T3/T4 are bound by albumin, TBG, and ?
Marijuana and methadone cause gynecomastia by dec ?
MC thyroid Ca
Elevated prolactin w/o clinical sx, lab should do?
Inhibin from sertoli cells inhibits GnRH and ?
ACTH dependent - next test?
Hemorrhage into pituitary - aka?
Rx that greatly increases iodine
Ending of Rx to tx: SIADH
toxic adenoma: tx in US w/ cure rate > 80%
Blue nevi, cardiac myxomas, schwannoma, testicle/ovary tumor
Hormone - dev of epididymis, vas def, seminal vesicle
Test for lack of diurnal rhythm of cortisol
androgen deficient in third trimester - sx?
Hyponatremia w/ hypoosmolarity, euvolemic
hormone - dev of prostate, ext genitalia
Adrenal layer - aldosterone
hyperpigmentation, striae, truncal obesity, hyperandrogenism
testicle in inguinal canal, undeveloped
elderly w/ weight loss, anorexia, constipation, tachy, afib, cognitive dysfunction
unique enzyme in glomerularis
unexplained hyperkalemia, age > 60
Adrenalytic Rx that can elevate liver enzymes
CRH does not stimulate, High Dose Dex does not suppress
Lack of ?results in impermeability of collecting duct to water/marked diuresis
Hyperthryoidism w/ very high mortality
First test to check for acromegaly
Thyroid Ca that invades blood vessels early
iodide is stored w/i thyroid as?
Pituitary adenoma, Parathyroid hyperplasia, Pancreatic neuroendocrine tumors
QuestionAnswerNotes
mediates most of the effects of GH on somatic growth
MCC secondary aldosterone deficiency
Cortisol + 11-beta-hydroxysteroid dehydrogenase = ?
AR dz involving epithelial Na channel
MCC painful thyroid goiter
MC pituitary lesion
48 hrs of Dex differentiates Cushing's from ?
HTN in Cushing's b/c cortisol activates the ? receptor
Test to assess functional status of thyroid tissue
primary AI effect on renin?
High estrogen states effect on TBG?
Tx for central DI
Rx: Inhibits growth hormone
Reduction in thyroid hormone levels from ingesting large amt iodine
endocrine condition w/ absolute eosinophilia
Tx: secondary and tertiry AI
men, permanent virilization of the hypothalamus occurs?
p450 cleaves cholesterol side chains to make?
Dx: high ESR, low TSH, High T4 >T3, Low anti=TPO/Tgb
weakness, N/V, weight loss, hyperpigmentation, vitiligo, orthostatic hypotension
Elevated GH/IGF-1 not suppressed by oral glucose tolerance test
Test for overproduction of cortisol
Tx: goiter w/ compressive sx in unhealthy individuals
Test for dec feedback inhibition of cortisol
aging causes which testicular deficiency?
dx: tufting of terminal phalanges
Vaccine preventable cause of acquired testicular damage
Painless woody goiter and sclerosing cholangitis
Gynecomastia w/ Inc LH, Inc T, nml TSH
Painless hyperthyroid -> hypothyroid that resolves after a year
Rx class: flutamide, finasteride, dutasteride
only synthetic corticosteroid not tested by the cortisol assay
polydipsia, polyuria, large urine volume, inappropriately dilute urine
ID Rx w/ SE of nephrogenic DI
prolactinoma sx but low serum prolactin due to?
Hyperthalamic temp instability w/ alt fevers
2nd adrenal insuff at delivery, in women w/ significant blood loss
 
In which gender is thyroid malignancy w/ nodule more likely?
skeleton type - androgen deficient before puberty?
Measured to release vasopressin at carotid sinus and aortic arch
Rx that causes goiter in 6% of chronic users
Acute or subacute thyroiditis: RAIU normal
male w/ female phenotype, lack axillary/pubic hair
Diffuse toxic goiter on RAIU (hot) - dx?
Adrenal layer - cortisol (more)
primary adrenal insuff - Na goes ?
5-alpha-reductase converts testosterone to ?
effect of insulin resistance on sex hormone binding globulin (SHBG)
cafe-au-lait spots, precocious puberty, acromegaly, thyrotoxicosis
MCC thyrotoxicosis
Neoplasia of the parafollicular cell
Rate limiting step for thyroid hormone synthesis
Way to measure central ACTH
Leydig cells produce which hormone?
QuestionAnswerNotes
Acts via cyclic AMP to inc permability of the tubular cell to water
dopamine receptor agonist
Test for HPA axis or GH axis deficiency
Persistent hyperkalemia w/o obv cause
MCC goiter and hypothyroid in US
Effect of amiodarone on RAIU
Gold standard for dx of adrenal insufficiency
DI-like sx but inc AVP w/ water deprivation and doesnt respond to DDAVP
Measured to release vasopressin at anterolateral hypothalamus
Worst form of Thyroid Ca
Psych Rx w/ SE of nephrogenic DI
dopamine agonist w/ SE: nausea, orthostasis
primary testicular failure - low testosterone, ? LH
Inheritance of Kallman's syndrome
ADH secreted by the ?
Exophthalmos, lytic bone lesions, DI
MCC primary adrenal insuff in western world
how to tell organic from psychogenic ED
priamry adrenal insuff - BUN goes ?
Test to Dx DI
Insulin tolerance test c/i in pt w/ sz and ?
Rx: block MR receptor
MCC tertiary adrenal insufficiency
Satiety signal
After pituitary surgery, change in water balance due to no?
Dx: CRH stim -> exaggerated rise in ACTH
Acromegaly - MCC death due to enlargement of?
2nd adrenal insufficiency lacks?
Useful for thyroid Ca surveillance post surgery and radioiodine ablation
Gynecomastia w/ Inc LH, Inc T, dec TSH
Test to dx papillary thyroid Ca
Tx acromegaly, failing somatostatin analogues
Hypothyroidism w/ very high mortality
Gynecomastia w/ nml LH, Dec T, nl PRL
SE: prim aldosterone deficiency - besides ACEI/ARBs
Test to evaluate thyroid nodularity
Adrenal layer - cortisol (less), DHEA, androstenedione
Psychoactive agent that can cause gynecomastia
Abnml migration of GnRH and olfactory neurons
acid base disturbance caused by 2nd hypoaldosteronism
how does hyperprolactinemia cause gynecomastia
DM, optic atrophy, deafness - also expect what sx?
The only pituitary adenoma where surgery is not considered first-line
Small but firm testicles - dx?
growth of lower jaw
Gynecomastia w/ Inc LH, Dec T
hypothalamus is derived from the ?
Adrenal dz caused by sarcoidosis
Common precursor increases prolactin due to decreased?
anosmia and lack of secual development
post adrenalectomy - risk of ?
escutcheon type - androgen deficient after puberty
bioavailable testosterone is NOT bound to?
Gynecomastia w/ inc hcg - concern for ?
21-hydroxylase deficiency aka?

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Created Nov 12, 2012ReportFavoriteNominate
Tags:endocrine, note

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